cloquintocet-mexyl 1,2-benzisothiazol-3(2H)-one FENOVA SUPER CHEMINOVA A/S P.O. Box 9 DK-7620 Lemvig Denmark Xi;R38 R43 N;R51/53

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1 .. 48X/ FENOXAPROP-P-ETHYL 69 g/l EW 2014 Cheminova A/S Phone (+45) FENOXAPROP-P-ETHYL 69 g/l EW :. 1. / FENOXAPROP-P-ETHYL 69 g/l EW cloquintocet-mexyl 1,2-benzisothiazol-3(2H)-one.. FENOVA SUPER CHEMINOVA A/S P.O. Box 9 Denmark sds@cheminova.dk (+45) (24 ; ) DPD. 1999/45/EC CLP 1272/2008 WHO R-. Xi;R38 R43 N;R51/53 : 2 (H315) : 1 (H317) : 2 (H411) U ( ) /45/EC... Xi N.

2 2 17 R- R38... R43... R51/53... S- S24... S37... S cloquintocet-mexyl 1,2-benzisothiazol-3(2H)-one,. /.. S2.... S S29... SP1.... (. ). 1272/ Fenoxaprop-P-ethyl 69 g/l EW cloquintocet-mexyl 1,2-benzisothiazol-3(2H)-one (GHS07, GHS09)... H H H EUH : SP1. (. ).

3 3 17 P P P302+P P333+P P P : : / PBT vpvb. 3. / 3.1., R-. Fenoxaprop-P-ethyl CAS : 7% Propanoic acid, 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]-, ethyl ester, (R)- CAS IUPAC (R)-Ethyl 2-[4-[(6-chloro-2-benzoxazolyl)oxy]phenoxy]propanoate ISO Fenoxaprop-P-ethyl EC (ELINCS no.) -- EU index no. -- DSD R50/53 CLP : 1 (H317) : 1 (H400) 1 (H410) Cl N O O O O O (% / ) CAS no. EC no. (EINECS no.) DSD CLP Solvent naphtha (petroleum), heavy aromatic Reg. no Alcohols, C9-C11, ethoxylated Xn;R65 R66 N;R51/53, Xn;R22 Xi;R41 R (H304) 2 (H411). 1 ( 302). 1 ( 318)

4 4 17 Cloquintoce tmexyl Reg. no.: ,2- Benzisothiazol- 3(2H)-one Xn;R22 R43 N;R50/53, Xn;R22 Xi;R38-41 R43 N;R50,. 4 (H302).. 1 (H317) 1 (H400) 1 ( 410). 4 (H302).. 2 (H315).. 1 (H318).. 1 (H317) 1 (H400) ,. :.. :...,,....., A. /. 5.

5 , :,, , ,.. ( 10 ): 1., 8 2., ,,,, ,...

6 GHS (Annex 4, Section 6).,.,,..., , ,., 8...,.,....

7 ,..,..,,,,...,,., ( ) / Solvent Naphtha... Fenoxaprop-P-ethyl DNEL... PNEC... Solvent naphtha DNEL, dermal... DNEL, inhalation... PNEC, aquatic environment ppm, mg/kg bw/day 0.01 mg/l 12.5 mg/kg bw/day 151 mg/m 3 Not applicable ,.

8 8 17,.,.,.,,.,..,...,, PE. PE ph... 6,3 25 C /... 0 C 100 C C (Pensky-Martens closed cup)... (Butyl acetate = 1) Solvent naphtha : < 0.01 ( / )... ( ) / Solvent naphtha : vol% ( kpa)... Fenoxaprop-P-ethyl : 5.3 x 10-7 Pa at 20 C Solvent naphtha : 13 Pa at 20 C 80 Pa at 55 C

9 (Air = 1) Solvent naphtha : > 1... : 1.03 g/ml ( )... fenoxaprop-p-ethyl : ethyl acetate > 380 g/l 20 C toluene > 480 g/l 20 C n-hexane 7.0 g/l 20 C 7.0 mg/l 20 C n- octanol/ Fenoxaprop-P-ethyl : log Kow = 4.28 Solvent naphtha : log Kow = C C mpa.s 20 C, , * =,....,. *. : ( ) - LD 50,, : > 2000 mg/kg (method OECD 425) - LD 50,, : > 2000 mg/kg (method OECD 402)

10 LC 50,, : > 4,96 mg/l/4 h (method OECD 403) /... / , Fenoxaprop-P-ethyl, :. (method OECD 404) :. (method OECD 405).* :. method OECD 429).* Fenoxaprop-P-ethyl ( 40%).,,......,. *. : ( ) - LD 50,, : mg/kg (method OECD 401) - LD 50,, : > 2000 mg/kg (method US-EPA 81-2) - LC 50,, : > mg/l/4 h (method OECD 403) /... (method US-EPA 81-5) /.. (method US-EPA 81-4). * STOT... (method US-EPA 81-6). Fenoxaprop-P-ethyl (8 ).* Fenoxaprop-Pethyl. Fenoxaprop-P-ethyl,.* Fenoxaprop-Pethyl (3 ). Fenoxaprop-P-ethyl ( ) (3 ).*,. *

11 11 17 STOT :,. NOAEL: 20 ppm (2 mg/kg../ ) 90 *. Solvent naphtha (petroleum), heavy aromatic....* : ( ) - LD 50,, : > 5000 mg/kg (method OECD 401) - LD 50,, : > 2000 mg/kg (method OECD 402) LC 50,, : > 4.8 mg/l (method OECD 403) /... /... (, method OECD 404). (, method OECD 405). * STOT... STOT... (, method OECD 406). * (, method OECD 471, 473, 474, 475, ). *, IARC.* (, method OECD 414). *.*. /. (, method OECD ). naphtha.

12 12 17 Alcohols, C9-C11, ethoxylated.... ( ) - LD 50,, : mg/kg - LD 50,, : > 2000 mg/kg (method OECD 402)* - LC 50,, : /... / STOT....* * Cloquintocet-mexyl.... : ( ) - LD 50,, : 1098 mg/kg (method OECD 425) - LD 50,, : > 2000 mg/kg (method OECD 402) - LC 50,, : > 5.05 mg/l (method OECD 403) / ((method OECD 404).* / (method OECD 405).* (method OECD 429). Chinese hamster s (method OECD 473). *. (method OECD 416) ( ).* STOT... STOT.* NOEL: 1000 mg/kg../ 28 (method OECD 410).*

13 ,2-Benzisothiazol-3(2H)-one... ( ) - LD 50,, : 670 mg/kg LD50,, : 784 mg/kg (method OPPTS ; 73% ) - LD 50,, : > 2000 mg/kg (method OPPTS % ) - LC 50,, : /.. (method OPPTS ). /. (method OPPTS ) (method OPPTS )...*,.*.. * ,., -, : - Rainbow trout (Oncorhynchus mykiss) h LC mg/l - Daphnids (Daphnia magna) h EC mg/l - - Green algae (Desmodesmus subspicatus) h EC 50 Duckweed (Lemna gibba)... 7-day LC mg/l 4.3 mg/l - Bobwhite quail (Colinus virginianus)... LD 50 > 2250 mg/kg - Eisenia foetida day LC mg/kg - Honey bee (Apis mellifera) h LD 50, oral 356 g /

14 h LD 50, contact 599 g/ Fenoxaprop-P-ethyl.. naphtha OECD Fenoxaprop-P-ethyl,. naphtha.. (BCF) Fenoxaprop-P-ethyl. naphtha PBT vpvb PBT vpvb (2008/98/EC),., 1..

15 15 17, ( ) ,,.,. 14. ADR/RID/IMDG/IATA/ICAO UN number UN...,, n.o.s. (Fenoxaprop-P-ethyl alkyl(c3-c6)benzenes) III II MARPOL 73/78 IBC /, Seveso I,. 2012/18/EU:

16 CAS Chemical Abstracts Service CLP Classification, Labelling and Packaging; refers to EU regulation 1272/2008 as amended Dir. Directive DNEL Derived No Effect Level DPD Dangerous Preparation Directive; refers to Dir. 1999/45/EC as amended DSD Dangerous Substance Directive; refers to Dir. 67/548/EEC as amended EC 50 50% Effect Concentration EINECS European Inventory of Existing Commercial Chemical Substances EW Emulsion, oil in water GHS Globally Harmonized classification and labelling System of chemicals, Third revised edition 2009 IARC International Agency for Research on Cancer IBC International Bulk Chemical code ISO International Organisation for Standardization IUPAC International Union of Pure and Applied Chemistry LC 50 50% Lethal Concentration LD 50 50% Lethal Dose MARPOL Set of rules from the International Maritime Organisation (IMO) for prevention of sea pollution ND Naphthalene Depleted NOAEL No Observed Adverse Effect Level NOEL No Observed Effect Level N.o.s. Not otherwise specified OECD Organisation for Economic Cooperation and Development OPPTS Office of Prevention, Pesticides and Toxic Substances PBT Persistent, Bioaccumulative, Toxic PE Polyethylene PNEC Predicted No Effect Concentration Reg. Regulation R-phrase Risk phrase SDS Safety Data Sheet SP Safety Precaution S-phrase Safety phrase STOT Specific Target Organ Toxicity US-EPA Environmental Protection Agency USA vpvb very Persistent, very Bioaccumulative WHO World Health Organisation : - :

17 17 17 : R-... R22 R38 R41 R43 R50 R50/53,. R51/53,. R52. R65. R66. CLP H H H318 H400. H EUH401..., Cheminova A/S.. : Cheminova A/S Safety, Health, Environment & Quality Department / GHB