34 7 ( ) V o l. 34 N o. 7 2006 7 Jour. of N o rthw est Sci2T ech U niv. of A gri. and Fo r. (N aṫ Sci. Ed. ) July 2006 4 Ξ 1, 2, 1, 3 (1, 712100; 2, 712100; 3, 730000) [ ] 4, [ ] ; ; ; ; ; ; [ ] O 629. 12 [ ] A [] 167129387 (2006) 0720096205 2 10,,, [122 ],, 20 80, [324 ],, [3, 526 ] 20 80,, [728 ] [2, 11213 ] 1 4 ( Iso2 m altoo ligo saccharide, IM O ) ( Soybean o ligo saccharide, SBO S) (F ructoo ligo saccharide, FO S) (Xyloo ligo saccharide, XO S) 4, 1, ;, ; [9210 ] 4 1 [2, 11213 ] T able 1 Chem ical compo sition of 4 k inds of functional o ligo saccharides T ype IM O SBO S FO S XO S M ono saccharide N um ber of mono sac2 charides Bonds indictive of functions Gluco se 2 5 Α21, 6 F ruc2 to se, galacto se, gluco se 2 4 Α21, 6 Sucro se, fructo se 2 5 Β21, 2 Functional components Iom al2 to trise, isom alto teto se, pano se Stachyo se, raffino se, surco se Kesto se, bi2 furcto se, kestopento se Xylo se 2 7 Α21, 4 Xylobio se, xylo trio se 2 2. 1, 20 10 % : 0. 4 0. 6, 0. 2 0. 7, 0. 3 Ξ [] 2006203231 [](1985- ),,, E2m ail: shanliran@ tom. com [](1971- ),,,,, E2m ail: gongyh01@ 163. com
7 : 4 97 0. 6, 0. 5 [2, 11 ], ;, ;, ;,, 4 [2, 11 ] 2. 2 [14215 ],, ; ;, ; 3,,, 4 2. 3, ph 2. 5 8. 0, 100 1 h [14 ] [14 ],, ph 3 4 3, 97%, ; [16217 ] [18 ] 2005 ph > 3, 140 [19 ], ph 5 7,, 150, ph < 4 [20221 ], ph 2. 4, [14 ], [22 ],, [11, 20 ] 3 3. 1 3. 1. 1( (S. m u tans) ),,,,,, [9, 23 ] [24 ],, (M odified Soybean O ligo saccharide),, [25 ] 3. 1. 2,, [26 ] [27 ],, 1995, [28 ] [29 ],,, ;,, [30 ] 3. 1. 3,, [31 ],,,,,, [32233 ] [34 ] 30 35 50 2, 30 35, ; 50 [35 ] [36 ],,, [37 ]
98 ( ) 34, [38 ], 0. 7 g, 3, 8. 5% 20. 2%, 15 g 8 g, 0. 05% 0. 07%, 1g20, 1g10 1g7 [39 ],,,, 3. 2 3. 2. 1 ( B i2 fidin,b ifilong ),, [40 ],,,, [40241 ],, [42 ],, [40 ], (SOD ),, 3. 2. 2,, Zn,M g, Fe, Ca [40 ] :, ph, ;,, [21 ], Ca [10211, 43244 ], Ca,,,,, Ca [21 ] 3. 2. 3, [20, 41242 ],,,,, [41 ] [45 ], [46 ],,, [47 ] 4,, 3. 2. 4, ph,, [21, 48 ],, [49 ],, [50 ],,, [25 ] 4,,,,,,,,,, ;,,,,
7 : 4 99,,, [4, 21 ],,,, [] [ 1 ] Kaneko T, Yokoyam a A, Suzuk im. D igestibility characteristics of isom altoo ligo saccharides in comparison w ith several saccharides using the rat jejunum loop m ethod[j ]. B io sci B io techno l B iochem, 1995, 59 (7) : 119021194. [ 2 ]. : [M ]. :, 1995. [ 3 ]. [J ]., 2002, 32 (3) : 56261. [ 4 ] N akakuk i. D evelopm ent of functional o ligo saccharides in Japan[J ]. T rends in Glyco science and Glyco techno logy, 2003, 15 (82) : 57264. [ 5 ],. [J ]., 2005, 8 (2) : 427. [ 6 ]. [J ]., 2003 (11) : 8210. [ 7 ],,. [J ]., 2004 (9) : 29231. [ 8 ]. [J ]., 2002 (4) : 66268. [ 9 ]. [J ]., 2004 (1) : 11214. [ 10 ]. [M ]. :, 2004. [ 11 ],,. [J ]., 2004 (1) : 20222. [ 12 ] A lonso J L, Dom nguez H, Garro te G, et al. Xyloo ligo saccharides: p roperties and p roduction techno logies[j ]. Electronic Journal of Evi2 ronm ental, A gricultural and Food Chem istry, 2003, 2 (1) : 2302232. [ 13 ],. [J ]., 2005, 37 (5) : 113821141. [ 14 ],,. [J ]., 2002 (1) : 56259. [ 15 ],. [J ]., 2004, 20 (3) : 2672269. [ 16 ]. [M ]. :, 1997. [ 17 ],,. [M ]. :, 2000. [ 18 ],. [J ]., 2005 (7) : 57260. [ 19 ]. [J ]., 2004 (2) : 34236. [ 20 ]. [J ]., 2005, 35 (2) : 50260. [ 21 ]. [M ]. :, 2004. [ 22 ],,,. [J ]., 2005 (3) : 962100. [ 23 ] M inam i T,M ik i T, Fujiw ara T, et al. Caries2inducing activity of isom altoo ligo sugar ( IM O S) in in v itro and rat experim ents[j ]. Shoni Shikagaku Zasshi, 1989, 27 (4) : 101021017. [ 24 ],. [J ]., 2003 (3) : 13216. [ 25 ],,. [J ]., 2002, 24 (3) : 3092310. [ 26 ] W ang H F, L im P S, Kao M D, et al. U se of isom alto2o ligo saccharide in the treatm ent of lip id p rofiles and constipation in hemodialysis patients[j ]. Journal of the Am erican Co llege of N utrition, 2001, 11 (2) : 73279. [ 27 ],,,. [J ]., 2003 (8) : 33234. [ 28 ] Kok N, Roberfro id M, D elzenne N. Imp rovem ent of lipogenesis in the low er VLDL secretion induced by o ligofructo se in rat[j ]. B r J N u2 tr, 1996, 76: 8812890. [ 29 ],,. [J ]., 2004, 8 (4) : 1222126. [ 30 ],. [J ]., 2005, 20 (1) : 65268. [ 31 ] Roy D. T echno logical aspects related to the use of bifidobacteria in dairy p roducts[j ]. D airy Science and T echno logy, 2005, 85: 39256. [ 32 ] Boehm G, L idestrim, Casetta P, et al. Supp lem entation of a bovine m ilk fo rm ula w ith an o ligo saccharide m ixture increases counts of fae2 cal bifidobacteria in p reterm infants[j ]. A rchives of D isease in Childhood Fetal and N eonatal Edition, 2002 (86) : 1782181. [ 33 ] Bouhnik Y, Rask ine L, Simoneau G, et al. T he capacity of nondigestible carbohydrates to stim ulate fecal bifidobacteria in healthy hu2 m ans: a double2blind, random ized, p lacebo2contro lled, parallel2group, do se2response relation study[j ]. Am erican Journal of C linical N u2 trition, 2004, 80 (6) : 165821664. [ 34 ],,,. [J ]., 2005, 20 (1) : 49251. [ 35 ],,,. [J ]., 2003, 15 (1) : 10212.
100 ( ) 34 [ 36 ],,,. [J ]., 2003, 15 (6) : 3212322. [ 37 ],,,. [J ]., 2005, 21 (1) : 1662169. [ 38 ],. [J ]., 2003, 19 (77) : 75278. [ 39 ],,,. [J ]., 2004 (1) : 46247. [ 40 ]. [J ]., 2002, 23 (10) : 1412142. [ 41 ],,. [J ]., 2005, 21 (4) : 83287. [ 42 ]. [J ]., 2005 (5) : 47248. [ 43 ] H euvel E G, Schaafsm a G,M uys T, et al. N ondigestible o ligo saccharides do no t interfere w ith calcium and nonhem e2iron abso rp tion in young, healthy m en [J ]. Am J C lin N utr, 1998, 67 (3) : 4452451. [ 44 ] M ineo H, H ara H, Kikuch i H, et al. V arious indigestible saccharides enhance net calcium transpo rt from the ep ithelium of the sm all and large intestine of rats in v itro[j ]. J N utr, 2001, 131 (12) : 324323246. [ 45 ],,. [J ]., 2003 (23) : 14215. [ 46 ],,,. [J ]., 2005 (6) : 2682272. [ 47 ],,. 4 [J ]., 2005 (4) : 9211. [ 48 ] Chen H L, L u Y H, L in J J, et al. Effects of isom alto2o ligo saccharides on bow el functions and indicato rs of nutritional status in constipat2 ed elderly m en [J ]. Journal of the Am erican Co llege of N utrition, 2001, 20 (1) : 44249. [ 49 ],,,. [J ]., 2002, 13 (1) : 62263. [ 50 ]. 30 [J ]., 2003, 26 (2) : 89. R esearch p rogress in 4 key functional o ligo saccharides SHAN L i-ran 1, GONG Y ue-hua 2, J IA J ian-guang 1,L UO Y ing- j ie 3 (1 T he N ational B ase of L if e S cience and B iotechnology E d ud ation,n orthw est A & F U niversity, Y ang ling, S haanx i 712100, Ch ina; 2 Colleg e of L if e S ciences,n orthw est A & F U niversity, Y ang ling, S haanx i 712100, Ch ina; 3 S chool of P harm acy, L anz hou U niversity,l anz hou, Gansu 730000, Ch ina) Abstract: T h is review in troduces 4 k inds of functional o ligo saccharides (isom altoo ligo saccharide, soy2 bean o ligo saccharide, fructoo ligo saccharide and xyloo ligo saccharide). T heir chem ical compo sition s, distribu2 tion s and function s are discu ssed. T he ex isting p rob lem s in research are analyzed, and finally the statu s and p ro spects are view ed. Key words: funct iona l o ligo saccha ride; isom a ltoo ligo saccha ride; soybean o ligo saccha ride; fruc2 too ligo saccharide; xyloo ligo saccharide; physical and chem ical p roperty; physio logical function