The recent deve lopm ent and scope fo r future of functiona l foods in J apan

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1 1 23 (1, ; 2, ) : 10, ( FOSHU) 500, FOSHU, FOSHU : FOSHU; ; : TS218 : A : (2006) The recent deve lopm ent and scope fo r future of functiona l foods in J apan YAN Zhang 1 BOD IHu i 2 ( 1 College of L ife Science, Cap ital Normal University, Beijing College of App lied A rts and Science, B eijing Union University, B eijing ) Abstract: In last 10 years, the species of FOSHU p roduct increased up to more than 500 in Japan. The current FOSHU p roducts can be categorized according to the mechanism of their functions in vivo. The recent development and scope for future of those two categories of the p roducts were outlined herewith. It was also emphasized in this review that the de2 velopment of FOSHU p roducts in future would be strongly supported and driven by p rogress in the filed of molecular biol2 ogy, especially p rogress in the development of biomarker. Key words: FOSHU; health claim; functional food , [ 1 ],, ( Functional food),,, : ; ; ,, ,,,, : :,,,, :, E - mail: bodi_ hui@ ygi1edu1cn 74

2 ( Foods for specified health uses, FOSHU ),, FOSHU 1991, : FOSHU, 1993 FOSHU : ; [ 1 4 ] FOSHU, FOSHU, , FO SHU 211, FOSHU (Health claim), FOSHU 2005, FOSHU, FOSHU, 1 1 [ 20 ] 212 ACE - EPA K 2 FOSHU:, ;,,, FOSHU, 80% 3 FO SHU, FOSHU, : 311 FOSHU, ( : ) FOSHU, 312, FOSHU - [ 5 ] FOSHU :,, FOSHU, [ 6 ],,,,, [ 7 ] :, 75

3 , : [ 8 ], ;, [ 9 ] FOSHU, 4 FO SHU, FOSHU, FOSHU :, FOSHU FOSHU, : 411 (MBP) FOSHU [ 10 ], MBP, MBP, MBP FOSHU, ( K 2 ) [ 11 ],, FOSHU, [ 12 ], FOSHU, 412,,, mrna, -, [ 13 ] FOSHU (ACE), ACE II [ 14 ] ACE, ACEFOSHU 5FO SHU, : FOSHU, FOS2 HU, :, FOSHU, FOSHU,,, FOSHU, FOSHU (B iomarker), FOSHU,, :,,,, :

4 , [ 15 ], FOSHU, DNA (M icro - array), FOSHU, FOSHU 6 FO SHU FOSHU :, FOSHU 611,, :,, [ ],, :, ( H1 pylori) [ 18 ] :,, FOSHU FOSHU :,,, (JAF I) JAF I JAF I, FOSHU :,, FOSHU,,,,, 612 : 60%, 2003,,,,,,, , : ; (1) (2) ; (3) ; (4) ; (5) FOSHU, [ 19 ] 77

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