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Prior Authorization July 2017 Please Note: Not all benefit plans include prior authorization. Check your plan materials to see if this information applies to you. What Is Prior Authorization? It s a quality and safety program that promotes the proper use of certain medications. If your doctor prescribes a medication that is included in our Prior Authorization program, you must get prior approval before your plan will cover your medication. We base the Prior Authorization program on U.S. Food and Drug Administration and manufacturer guidelines, medical literature, safety, accepted medical practice, appropriate use and benefit design. Prior Authorization only affects the medication that your benefit plan covers. You and your doctor should make the final decision about the medication that is right for you. Which Medications Are Included? This list includes both specialty and non-specialty drugs that require prior authorization. You will also find information on where your doctor should send a request for prior authorization. What Are the Possible Outcomes of a Prior Authorization Request? If you meet the requirements, your drug will be approved and we will cover it. Your drug may be approved for up to one year or more. You will be sent a letter letting you know that your drug has been approved. If you do not meet the requirements, your prior authorization will be denied. Also, if your doctor does not send in the requested information within a certain period of time, your prior authorization will be denied. If your request is denied, both you and your doctor will be sent a letter explaining the denial. The letter will include information about how you can appeal the decision. What Happens at the Pharmacy? The pharmacist enters your prescription information into the computer system. If your medication needs prior authorization and you already have it, the pharmacist will fill your prescription. If you do not have prior authorization, you have three choices: You or your pharmacist can call your doctor and get a prescription for a different medication that does not need prior authorization. You can pay full price for your medication. You or your pharmacist can ask your doctor to get prior authorization for you. If you do not meet the requirements for prior authorization, you can still choose another option. If you submit your prescription to your plan s mailorder pharmacy and do not get prior authorization, the pharmacy will not fill your prescription. You will receive notification by mail. What Happens at a Specialty Pharmacy? Usually, your doctor will call or fax a prescription directly to the specialty pharmacy. If your prescription requires prior authorization, the specialty pharmacy will tell your doctor how to request this. Prior Authorization List Effective 7/1/17 1

Prior Authorization List Specialty Drugs Preferred drugs are listed with a (#). Drugs listed with a (+) require medical necessity prior authorization see Table A for more information. If required, your doctor should request prior authorization for your drug based on how it will be billed and covered. For Drugs Billed Under the Pharmacy Benefit These specialty drug prior authorization requests go to CVS/specialty at 800-237-2767 (phone) or 866-249-6155 (fax). CVS/specialty is a division of CVS Health, an independent company that provides pharmacy services on behalf of your health plan. Please see the Excluded Drug List for specialty drugs that are not covered. For Drugs Billed Under the Medical Benefit Your doctor should request prior authorization through CVS/caremark s Novologix medical prior authorization system. Your doctor can access this system by signing onto your health plan s provider portal. Abraxane Actemra (#+) Acthar HP Actimmune Adagen Adcetris Adcirca (+) Adempas (#) Advate Adynovate Afinitor Aldurazyme Alecensa Alimta Alphanate Alphanine SD Alprolix Ampyra (#) Apokyn Aralast NP Aranesp Arcalyst Arzerra Astagraph XL Aubagio (+) Avastin Aveed Avonex (+) Azacitidine (#) Bebulin VH Beleodaq Bendeka Benefix Benlysta Berinert Betaseron (#) Bethkis Bexarotene (#) Bivigam Blincyto Botox Bravelle (+) Buphenyl Cabometyx Capecitabine (#) Caprelsa Carbaglu Carimune NF Cayston Cerdelga Cerezyme Cetrotide Cholbam Cimzia (+) Cinryze Coagadex Cometriq Copaxone 20mg (+) Copaxone 40mg (#) Copegus Cosentyx (+) Cotellic Cyramza Cystadane Cystagon Cystaran Dacogen Darzalex Decitabine (#) Deferoxamine (#) Desferal Docefrez Docetaxel (#) Dofetilide (#) Duopa Dysport Egrifta Elaprase Elelyso Eligard Eloctate Eloxatin Empliciti Enbrel (#) Entecavir (#) Entyvio (+) Epogen Epoprostenol sodium (#) Erbitux Erivedge Erwinaze Esbriet Euflexxa (+) Exjade Extavia (+) Eylea Fabrazyme Farydak Feiba NF Ferriprox Firazyr Firmagon Flebogamma Flolan Follistim AQ (+) Folotyn Forteo (#) Fusilev Gamastan S/D Gammagard S/D Gammagard Gammaked Gammaplex Gamunex C Ganciclovir (#) Ganirelix Gattex Gazyva Gel-One (#) Gemcitabine Gemzar Genotropin (+) Gilenya (#) Gilotrif Glassia Glatopa (#) Gleevec (+) Gonal-F (#) Granix Grastek Halaven Helixate FS (+) Hemofil-M Herceptin Hetlioz Hizentra Humate-P Humatrope (#) Humira (#) Hyalgan (#) Hycamtin Hydroxyprogesterone (#) HyQvia Ibrance Iclusig Ilaris Illuvien Imatinib (#) Imbruvica Incivek Increlex Infergen Inflectra (+) Inlyta Intron-A Iressa Istodax Ixempra Ixinity Jadenu Jakafi Jevtana Juxtapid (+) Kadcyla Kalbitor Kalydeco Kanuma Keytruda Kineret (+) Kitabis Pak Koate-DVI Kogenate FS (#) Korlym Krystexxa Kuvan Kynamro (+) Kyprolis Lartruvo Lemtrada Lenvima Letairis (#) Leukine Leuprolide (#) Lonsurf Lucentis Lumizyme Lupaneta Lupron Depot/ PED Luveris Lynparza Macugen Makena (#) Matulane (#) Mekinist Menopur Mitoxantrone HCI inj Moderiba (+) Monoclate-P Mononine Monovisc (+) Mozobil Myfortic Myobloc Myozyme Naglazyme Natpara Neulasta Neumega Neupogen (+) Nexavar Ninlaro Norditropin (#) Northera Novantrone Novoeight Novoseven Nplate Nutropin/AQ (+) Obizur Octagam Octreotide Acetate Odomzo Ofev Olysio Omnitrope (+) Oncaspar Onivyde Opdivo Opsumit (+) Oralair Orencia IV/SC (+) Orenitram Orfadin Orkambi Orthovisc (+) Otezla (+) Otrexup Ovidrel Ozurdex Pamidronate Disodium (#) Pegasys (#) PEG-Intron (+) Perjeta Plegridy (+) Pomalyst Prialt Privigen Procrit (#) Procysbi Profilnine SD Proleukin Prior Authorization List Effective 7/1/17 2

Prolia Promacta Provenge Pulmozyme Purixan Qutenza Ragwitek Rasuvo Ravicti Rebetol (+) Rebif (#) Rebif Rebidose (#) Reclast Recombinate Regranex Remicade (+) Remodulin Repatha (#) Repronex Retisert Revatio (+) Revlimid Ribapak (+) Ribasphere Ribatab Ribavirin (#) Riluzole (#) Rituxan (+) Rixubis Ruconest Sabril Saizen (+) Samsca Sandimmune Sandostatin/LAR Sensipar (#) Serostim Signifor LAR Sildenafil (#) Simponi/Aria (+) Sirolimus (#) Soliris Somatuline Depot Somavert Sovaldi Spinraza Sprycel Stelara (+) Stimate Stivarga Strensiq Supartz FX (#) Supprelin LA Sutent Sylatron Sylvant Synagis Synribo Synvisc/One (+) Tafinlar Tagrisso Tarceva Targretin Tasigna Taxotere Tecentriq Tecfidera (#) Temodar (+) Temozolomide (#) Tetrabenazine (#) Thalomid IV Thalomid PO Tikosyn (+) TOBI/Podhaler (+) Tobramycin (#) Topotecan Torisel Tracleer (#) Treanda Trelstar Tykerb Tysabri (+) Tyvaso Valchlor Valstar Vandetanib Vantas Vectibix Velcade Veletri Venclexta Ventavis Victrelis Vidaza Viekira Pak/XR (#) Vimizim Visudyne Vivaglobin Voriconazole (#) Votrient VPRIV Wilate Winrho SDF Xalkori Xeljanz/XR (+) Xeloda (+) Xenazine (+) Xeomin Xgeva Xiaflex Xolair Xtandi Xyntha Xyrem Yervoy Zaltrap Zarxio Zavesca Zelboraf Zemaira Zoladex Zoledronic acid (#) Zolinza Zomacton (+) Zometa Zorbtive Zydelig Zykadia Zytiga Condition/Drug Class Table A: Specialty Drugs Requiring Medical Necessity Prior Authorization Before you have coverage for one of these drugs you must have tried one ( or more) of these alternative drugs first. Brain Cancer Temodar temozolomide Colon Cancer Xeloda capecitabine Cystic Fibrosis TOBI/TOBI Podhaler Tobramycin inhalation Decrease in White Blood Cells Growth Deficiency Neupogen Genotropin, Nutropin/AQ, Omnitrope, Saizen, Zomacton Zarxio Humatrope, Norditropin, Flexpro Heart Arrhythmia Tikosyn dofetilide Hemophilia Helixate FS Kogenate High Cholesterol Juxtapid, Kynamro Repatha Huntington s Disease Xenaxine tetrabenazine Infertility Bravelle, Follistim AQ Gonal-F (all) Inflammatory Conditions (Crohn s Disease, Psoriasis, Rheumatoid Arthritis) Actemra, Cimzia, Cosentyx, Entyvio, Inflectra, Kineret, Orencia, Otezla, Remicade, Rituxan, Simponi/Aria, Stelara, Xeljanz/XR Enbrel and Humira Leukemia/Multiple Cancers Gleevec imatinib Multiple Sclerosis (A) Pulmonary Arterial Hypertension (A) Pulmonary Arterial Hypertension (B) Aubagio, Avonex, Extavia, Plegridy, Tysabri Betaseron, Copaxone 40mg, Gilenya, glatopa, Rebif, Tecfidera Multiple Sclerosis (B) Copaxone 20mg glatopa Osteoarthritis of the Knee Euflexxa, Monovisc, Orthovisc, Synvisc/One Gel-One, Hyalgan, Supartz Adcirca, Revatio Opsumit sildenafil Letairis, Tracleer Prior Authorization List Effective 7/1/17 3

Prior Authorization Non-Specialty Drugs Drugs listed with a (+) require medical necessity prior authorization see Table B for more information. Prior authorization requests go to CVS/caremark at 800-294-5979 (phone) or 888-836-0730 (fax). Please see the Excluded Drug List for drugs that are not covered. Abstral Actiq Altoprev (+) Ambien/CR (+) Amitiza (+) Amrix (+) Anadrol-50 Androgel (+) Apidra (+) Atacand/HCT (+) Avalide (+) Avapro (+) Avita (patients 30 and over) Basaglar (+) Beconase AQ (+) Belsomra (+) Benicar/HCT (+) Buprenorphine Byetta (+) Celebrex Chorionic gonadotropin Compound Drugs (costing $300 or more) Cozaar (+) Crestor (+) Detrol/LA (+) Differin (patients 30 and over) Diovan/HCT (+) Ditropan XL (+) Dulera (+) Dymista (+) Edarbi (+) Edarbyclor (+) Edluar (+) Epanova Evekeo Fabior Fentora Flonase (+) Fortamet (brand & generic) (+) Fortesta+ Glumetza (generic) (+) Gralise (+) Humalog (+) Humulin (except U-500) (+) Hyzaar (+) Incruse Ellipta (+) Intermezzo (+) Invokamet/XR (+) Invokana (+) Jentadueto (+) Jentadueto XR (+) Kazano (+) Lazanda Lescol/XL (+) Levemir (+) Lidocaine (generic) Lidoderm Lipitor (+) Livalo (+) Lotronex Lovaza Lumigan (+) Lunesta (+) Mevacor (+) Micardis/HCT (+) Myrbetriq (+) Naprelan (+) Nasacort AQ (+) Nasonex (+) Natesto (+) Nesina (+) Nuvigil (+) Oleptro (+) Olux-E (+) Omnaris (+) Omtryg Onsolis Oseni (+) Oxandrin Oxytrol (+) Pradaxa (+) Pravachol (+) Proscar Qnasl (+) Rayos (+) Rhinocort Aqua (+) Riomet (+) Sanctura (+) Savaysa (+) Seebri (+) Silenor (+) Sonata (+) Soriatane Sporanox Oral Capsules & Solution Sprix (+) Subsys Sustol Tanzeum (+) Tazorac Tekturna/HCT (+) Test Strips (all but OneTouch) (+) Testim (+) Teveten/HCT (+) Toviaz (+) Tradjenta (+) Tresiba (+) Tretin-X (patients 30 and over) Trulicity (+) Tudorza Pressair (+) Vascepa Veltin Veramyst (+) Viberzi (+) Vogelxo (+) Vytorin (+) Zetonna (+) Zipsor (+) Zocor (+) Zohydro Zolpimist (+) Zorvolex (+) Condition/Drug Class Table B: Non-Specialty Drugs Requiring Medical Necessity Prior Authorization Before you have coverage for one of these drugs you must have tried one ( or more) of these alternative drugs first. Arthritis/Pain Naprelan, Sprix, Zipsor, Zorvolex generic NSAIDs Asthma/COPD (A) Dulera Advair, Symbicort Asthma/COPD (B) Incruse Ellipta, Seebri, Tudorza Pressair Spiriva, Spiriva Respimat Blood Clots Savaysa, Pradaxa Xarelto, Eliquis Cholesterol Lowering (high potency) Cholesterol Lowering Crestor, Vytorin Altoprev, Lescol/XL, Lipitor, Livalo, Mevacor, Pravachol, Zocor Atorvastatin, ezetimibe/simvastatin (generic for Vytorin), rosuvastatin atorvastatin, fluvastatin, fluvastatin ext-rel, lovastatin, pravastatin, rosuvastatin, simvastatin Corticosteroids Rayos Immediate-release generic prednisone Depression Oleptro trazodone Dermatologic Olux-E Clobetasol propionate foam 0.05% Diabetes (Insulin) All Apidra, Humalog and Humulin (except U-500) Novolog, Novolin Diabetes (long-acting insulin) Basaglar, Levemir, Tresiba Lantus, Toujeo Prior Authorization List Effective 7/1/17 4

Condition/Drug Class Diabetes (Biguanides) Diabetes (DPP-4) Before you have coverage for one of these drugs Fortamet (brand & generic), Glumetza (generic), Riomet Kazano, Nesina, Oseni, Tradjenta, Jentadueto/XR you must have tried one ( or more) of these alternative drugs first. metformin/xr (generics for Glucophage/XR) Januvia, Janumet/XR, Onglyza, Kombiglyze Diabetes (SGLT2) Invokana, Invokamet/XR Farxiga, Jardiance, Synjardy/XR, Xigduo XR Diabetes (GLP-1) Byetta, Tanzeum, Trulicity Bydureon, Victoza Diabetes Supplies All test strips other than One Touch* OneTouch Glaucoma Hypertension Irritable Bowel Syndrome (constipation predominant) Lumigan Atacand/HCT, Avapro, Avalide, Benicar/HCT, Cozaar, Hyzaar, Diovan/HCT, Edarbi, Edarbyclor, Micardis/HCT, Tekturna/HCT, Teveten/HCT Amitiza lantanoprost, travoprost, Travatan Z, Zioptan generic ARBs Generic lomotil, immodium, Linzess Irritable Bowel Syndrome (diarrhea predominant) Viberzi Generic lomotil, immodium Muscle Relaxants Amrix cyclobenzaprine Nasal Steroids Overactive Bladder Sleep Medications Testosterone Replacement Beconase AQ, Dymista, Flonase, Nasacort AQ, Nasonex, Omnaris, Qnasl, Rhinocort AQ, Veramyst, Zetonna Detrol/LA, Ditropan XL, Myrbetriq, Oyxtrol, Toviaz Ambien/CR, Belsomra, Edluar, Intermezzo, Lunesta, Silenor, Sonata or Zolpimist Androgel, Fortesta, Natesto, Testim, Vogelxo budesonide nasal spray, flunisolide, fluticasone nasal, mometasone furoate nasal spray, triamcinolone oxybutynin ext-rel, tolterodine, tolterodine ext-rel, trospium, trospium ext-rel, Gelnique, Vesicare eszopiclone, zolpidem, zolpidem ext-rel, zaleplon Androderm, Axiron, testosterone gel (generic Fortesta) *Members on insulin pumps that require specific test strips other than OneTouch may be granted a lifetime approval to continue to fill their current test strips. Your benefit document defines actual benefits available and may exclude coverage for certain drugs listed here. Check your benefit information to verify coverage or view your personal benefit information on our website. This list may contain trademarks or registered trademarks of pharmaceutical manufacturers that are not affiliated with your health plan. This list may change or expand from time to time without prior notice. When we list brand-name drugs, programs may also apply to any available generic equivalents. Prior Authorization List Effective 7/1/17 5

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