Barbara P. Yawn, MD, MSc a, Susan K. Brenneman, PhD b, Felicia C. Allen-Ramey, PhD b, Michael D. Cabana, MD, MPH c, Leona E. Markson, ScD b a Department of Research, Olmsted Medical Center, Rochester, Minnesota; b Outcomes Research and Management, Merck & Co, Inc, West Point, Pennsylvania; c Division of General Pediatrics, University of California, San Francisco, California (asthma); (assessment); (asthma severity); (asthma control); (children) NAEPP = National Asthma Education and Prevention Program GINA = Global Initiative for Asthma FEV1 = forced expiratory volume in 1 second ATAQ = Asthma Therapy Assessment Questionnaire ACT = Asthma Control Test 41
480 F EV [1] [2 8] 1991 (NAEPP) [9 15] [16, 17] 1991 ( ) ( ) [2] [2] 1997 NAEPP ( 1) ( ) 1996 2005 Medline 1 [2 4] 1 2 / wk PEF 2 / mo FEV 1 PEF 80% PEF 20% 2 2 /wk <1 /d 2 / mo FEV 1 PEF 80% PEF 20% 30% 3 2 / wk 1 / wk 60% FEV 1 80% β- PEF 30% 4 FEV 1 PEF 60% PEF 30% 42 YAWN et al
[24 26] 5 2002 [3] [27] NAEPP NAEPP (< 8 10 ) [28] [4 7] [6] [29] (GINA) [4] [30 31] 1 (FEV 1 ) FEV 1 /FVC <5 7 [2, 32, 33] FEV 1 [18, 19] FEV 1 [34 39] [9, 20] NAEPP FEV 1 [34, 40] [41 45] [21 23] 43
ATAQ 5 17 [60] ATAQ 13 y [9, 46, 47] ( 7 ( 4wk) ( 12 wk) ) 0 0 3 Skinner [60] ATAQ ATAQ [11, 61 66] ATAQ 1996 ATAQ Cockcraft [48] [65, 67] ACT [57] 5 12 [49, 50] ACT 4wk [49] 5 ( ) 25 ( ) 19 [68, 69] 12 17 ACT FEV 1 ACT [69] ATAQ GINA Bateman [59] [51 57] [58] Bateman [59] ( ) GINA 1y 12 (ATAQ) (ACT) 44 YAWN et al
2 ( ) ATAQ ACT GINA Skinner [60] Nathan [57] Bateman [59] / 5 17 12 12 7 5 7 4wk 4wk 12 mo a b c a b c ( ) [69 70] [70] 2 1991 [71 73] 2002 [2, 3, 74] [4 6, 8] 45
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