GeneCopoeia provides five qpcr array formats (A, B, C, D, and E) suitable for use with the following realtime

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1 GeneCopoeia TM Expressway to Discovery ExProfile TM Human Breast Cancer Gene qpcr Array For focused group profiling of human breast cancer related genes expression Cat. No. QG063-A (6 x 96-well plate, Format A) Cat. No. QG063-B (6 x 96-well plate, Format B) Cat. No. QG063-C (6 x 96-well plate, Format C) Cat. No. QG063-D (6 x 96-well plate, Format D) Cat. No. QG063-E (6 x 96-well plate, Format E) Available as 1 set or 6 sets. Each set contains 504 unique gene primers deposited in six 96-well plates. Introduction The ExProfile human breast caner gene qpcr array profiles 504 human genes to aberrantly expressed human genes involved in human breast caner. These genes are carefully chosen for their close cancer correlation based on a thorough literature search of peer-reviewed publications. Abnormal gene expression is often observed in cancer development and progression. The ExPofile human breast caner gene array allows researchers to study the cancer-related genes to gain understanding of their roles in breast caner pathogenesis. QG063 plate 01: 84 unique gene PCR primer pairs QG063 plate 02: 84 unique gene PCR primer pairs QG063 plate 03: 84 unique gene PCR primer pairs QG063 plate 04: 84 unique gene PCR primer pairs QG063 plate 05: 84 unique gene PCR primer pairs QG063 plate 06: 84 unique gene PCR primer pairs Shipping and storage condition Shipped at room temperate Stable for at least 6 months when stored at -20 C Array format GeneCopoeia provides five qpcr array formats (A, B, C, D, and E) suitable for use with the following realtime cyclers. Important note: Upon receiving, please check to make sure that the correct array format was ordered to ensure the compatibility with your qpcr instrument. Plate format Instrument provider qpcr instrument model A (96-well) B (96-well) C (96-well) D (96-well) E (96-well) Applied Biosystems Applied Biosystems Bio-Rad Laboratories Bio-Rad Laboratories Roche Applied Science 5700, 7000, 7300, 7500, 7700, 7900HT (Standard 96-well block), ViiA TM 7 (Standard 96-well block) 7500 (Fast block), 7900HT (Fast block), StepOnePlus TM, ViiA TM 7(Fastblock) icycler iq,myiq,iq 5 CFX96, DNA Engine Opticon, DNA Engine Opticon 2, Chromo4 LightCycler 480 (96-well block) 1

2 Quality control 1. Each pair of primers in the ExProfile gene qpcr array has been experimentally validated to yield a single dissociation curve peak and to generate a single amplicon of the correct size for the targeted gene. 2. The positive PCR controls (PCR) have been verified to amplify a single amplicon of the correct size with Ct values around 20±2. 3. The Spike-in reverse transcription controls (RT) have been verified to amplify a single amplicon of the correct size with Ct values around 20±3. 4. R 2 > 0.99 was observed for high inter/ intra-array reproducibility. Materials required but not provided All-in-One TM First-Strand cdna Synthesis Kit All-in-One TM qpcr Mix Total RNA extraction kit (RNAzol RT RNA extraction reagent is recommended) DNase/RNase free tips, PCR reaction tubes, 1.5 ml microcentrifuge tubes 5 ml and 10 ml graduated pipettes, beakers, flasks, and cylinders 10 μl to1,000μl adjustable single channel micropipettes with disposable tips 5 μl to20μl adjustable multichannel micropipette, disposable tips, and reservoir qpcr instrument, compatible with gene qpcr arrays ordered Array layout Figure1. Illustration of QG063 plate 01 Figure2. Illustration of QG063 plate 02 Figure3. Illustration of QG063 plate 03 2

3 Figure4. Illustration of QG063 plate 04 Figure5. Illustration of QG063 plate 05 Figure6. Illustration of QG063 plate 06 Gene primer pairs: 84 wells (A row to G row) are designated for a real-time PCR assay for genes (see the primer list). HK1-6: Six pre-deposited housekeeping gene (HK1-6) primer pairs, which can be used as endogenous positive controls as well as for array normalization. GDC: Genomic DNA controls, which can be used to specifically detect genomic DNA contamination with a high level of sensitivity. RT: Spike-in reverse transcription controls, which can be used to monitor the efficiency of the RT reactions. These pre-deposited primer pairs specifically amplify the cdna template reversed transcribed from the spike-in control RNA in the sample. PCR: Positive PCR controls, which are used to verify the PCR efficiency by amplifying the predeposited DNA template with its specific pre-deposited primer pairs. Gene primer list Plate Position Catalog No. of Primer Accession No. of Gene Symbol QG A01 HQP NM_ BRCA2 QG A02 HQP NM_ TP53 QG A03 HQP NM_ CHEK2 QG A04 HQP NM_ XRCC1 QG A05 HQP NM_ CYP17A1 3

4 4 QG A06 HQP NM_ CYP1B1 QG A07 HQP NM_ ESR1 QG A08 HQP NM_ XRCC3 QG A09 HQP NM_ COMT QG A10 HQP NM_ SULT1A1 QG A11 HQP NM_ CYP1A1 QG A12 HQP NM_ CYP19A1 QG B01 HQP NM_ SOD2 QG B02 HQP NM_ TGFB1 QG B03 HQP NM_ VDR QG B04 HQP NM_ CYP2D6 QG B05 HQP NM_ MTHFR QG B06 HQP NM_ ERCC2 QG B07 HQP NM_ NAT2 QG B08 HQP BC FGFR2 QG B09 HQP NM_ NBN QG B10 HQP NM_ TNF QG B11 HQP NM_ IGF1 QG B12 HQP NM_ MDM2 QG C01 HQP NM_ AR QG C02 HQP NM_ ESR2 QG C03 HQP NM_ PGR QG C04 HQP NM_ CCND1 QG C05 HQP NM_ VEGFA QG C06 HQP NM_ ABCB1 QG C07 HQP NM_ XRCC2 QG C08 HQP NM_ CASP8 QG C09 HQP NM_ IGFBP3 QG C10 HQP NM_ PIK3CA QG C11 HQP NM_ ERCC4 QG C12 HQP NM_ MAP3K1 QG D01 HQP NM_ PTGS2 QG D02 HQP NM_ CYP3A5 QG D03 HQP NM_ HSD17B1 QG D04 HQP NM_ BARD1 QG D05 HQP NM_ NQO1 QG D06 HQP NM_ LIG4 QG D07 HQP NM_ NOS3 QG D08 HQP NM_ XPC QG D09 HQP NM_ EGFR QG D10 HQP NM_ IL6 QG D11 HQP NM_ TYMS QG D12 HQP NM_ CDKN2A QG E01 HQP NM_ ERCC5 QG E02 HQP NM_ IL10 QG E03 HQP NM_ LEPR QG E04 HQP NM_ LSP1 QG E05 HQP NM_ NCOA3

5 5 QG E06 HQP NM_ CDH1 QG E07 HQP NM_ CYP2C19 QG E08 HQP NM_ AHR QG E09 HQP NM_ MMP2 QG E10 HQP NM_ MPO QG E11 HQP NM_ MTR QG E12 HQP NM_ SERPINE1 QG F01 HQP NM_ RAD52 QG F02 HQP NM_ RAD50 QG F03 HQP NM_ ADH1B QG F04 HQP NM_ CYP2C9 QG F05 HQP NM_ IRS1 QG F06 HQP NM_ SHBG QG F07 HQP NM_ SRD5A2 QG F08 HQP BC TGFBR1 QG F09 HQP NM_ XRCC4 QG F10 HQP NM_ NAT1 QG F11 HQP NM_ ADH1C QG F12 HQP NM_ CYP11A1 QG G01 HQP NM_ EPHX1 QG G02 HQP NM_ APEX1 QG G03 HQP NM_ IGFBP1 QG G04 HQP NM_ IL1B QG G05 HQP NM_ ITGB3 QG G06 HQP NM_ MLH1 QG G07 HQP NM_ OGG1 QG G08 HQP NM_ PHB QG G09 HQP NM_ ZNF350 QG G10 HQP NM_ SIPA1 QG G11 HQP NM_ NR1I2 QG G12 HQP NM_ CDK4 QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR QG A01 HQP NM_ CCNE1 QG A02 HQP NM_ CCND2 QG A03 HQP NM_ XRCC5 QG A04 HQP NM_ TXNRD1 QG A05 HQP NM_ TXN

6 6 QG A06 HQP NM_ SOD1 QG A07 HQP NM_ CXCL12 QG A08 HQP NM_ RAD51C QG A09 HQP NM_ BACH1 QG A10 HQP NM_ PPARG QG A11 HQP NM_ ATR QG A12 HQP NM_ MRE11A QG B01 HQP NM_ MMP3 QG B02 HQP NM_ MMP1 QG B03 HQP NM_ LEP QG B04 HQP NM_ FASLG QG B05 HQP NM_ IGF1R QG B06 HQP NM_ GH1 QG B07 HQP NM_ TXN2 QG B08 HQP NM_ XRCC6 QG B09 HQP NM_ ERCC6 QG B10 HQP NM_ EP300 QG B11 HQP NM_ CYP2B6 QG B12 HQP NM_ PARP1 QG C01 HQP NM_ TXNRD2 QG C02 HQP NM_ CDKN2D QG C03 HQP NM_ IGFALS QG C04 HQP BC HLA-DRB1 QG C05 HQP NM_ GSTO1 QG C06 HQP NM_ CBR3 QG C07 HQP NM_ WRN QG C08 HQP NM_ UGT2B7 QG C09 HQP NM_ SULT1E1 QG C10 HQP NM_ BLM QG C11 HQP NM_ BCL2 QG C12 HQP NM_ RB1 QG D01 HQP NM_ PPARBP QG D02 HQP NM_ GHRL QG D03 HQP NM_ NME1 QG D04 HQP NM_ MYC QG D05 HQP NM_ MMP9 QG D06 HQP NM_ LIG1 QG D07 HQP NM_ KDR QG D08 HQP NM_ IL8 QG D09 HQP NM_ IL1A QG D10 HQP NM_ APOE QG D11 HQP NM_ APC QG D12 HQP NM_ MSH6 QG E01 HQP NM_ GSTM3 QG E02 HQP NM_ GSR QG E03 HQP NM_ GPX4 QG E04 HQP NM_ FANCD2 QG E05 HQP NM_ ERCC1

7 7 QG E06 HQP NM_ CTLA4 QG E07 HQP NM_ CHEK1 QG E08 HQP NM_ CDKN2C QG E09 HQP NM_ CDK2 QG E10 HQP NM_ DNMT3B QG E11 HQP NM_ SST QG E12 HQP NM_ UGT2B15 QG F01 HQP NM_ CLCA2 QG F02 HQP NM_ NCOR1 QG F03 HQP NM_ ADIPOQ QG F04 HQP NM_ PERLD1 QG F05 HQP NM_ PTTG1 QG F06 HQP NM_ MBD2 QG F07 HQP NM_ CBS QG F08 HQP NM_ CBR1 QG F09 HQP NM_ AKR1C3 QG F10 HQP NM_ PPP1R1B QG F11 HQP NM_ BAP1 QG F12 HQP NM_ COL18A1 QG G01 HQP NM_ TTK QG G02 HQP NM_ TOP2A QG G03 HQP NM_ BUB1B QG G04 HQP NM_ TERF2 QG G05 HQP NM_ TERF1 QG G06 HQP NM_ TEP1 QG G07 HQP NM_ SSTR2 QG G08 HQP NM_ SKP2 QG G09 HQP NM_ SHC1 QG G10 HQP NM_ RNASEL QG G11 HQP NM_ RAD51L1 QG G12 HQP NM_ RAD23B QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR QG A01 HQP NM_ PTPRJ QG A02 HQP NM_ PTGS1 QG A03 HQP NM_ PTGIS QG A04 HQP NM_ PTGDS QG A05 HQP NM_ PTEN

8 8 QG A06 HQP NM_ PRL QG A07 HQP NM_ ECHDC1 QG A08 HQP NM_ FBXW7 QG A09 HQP NM_ KIAA1794 QG A10 HQP NM_ PON1 QG A11 HQP NM_ POLD1 QG A12 HQP NM_ ADIPOR1 QG B01 HQP NM_ NPAS2 QG B02 HQP NM_ NQO2 QG B03 HQP NM_ NFKBIA QG B04 HQP NM_ MUC1 QG B05 HQP NM_ MTRR QG B06 HQP NM_ STS QG B07 HQP NM_ LIG3 QG B08 HQP NM_ ITGB4 QG B09 HQP NM_ IL1RN QG B10 HQP NM_ KLK3 QG B11 HQP NM_ HSD17B2 QG B12 HQP NM_ HRAS QG C01 HQP NM_ ACACA QG C02 HQP NM_ HIF1A QG C03 HQP NM_ HFE QG C04 HQP NM_ HDAC2 QG C05 HQP NM_ GSTZ1 QG C06 HQP NM_ GSTM2 QG C07 HQP NM_ GSTA2 QG C08 HQP NM_ GNB3 QG C09 HQP NM_ GLO1 QG C10 HQP NM_ GHRH QG C11 HQP NM_ GC QG C12 HQP NM_ POT1 QG D01 HQP NM_ IKZF3 QG D02 HQP NM_ FGFR4 QG D03 HQP NM_ ALDH3A1 QG D04 HQP NM_ FANCF QG D05 HQP NM_ FANCC QG D06 HQP NM_ ALDH1A1 QG D07 HQP NM_ F5 QG D08 HQP NM_ F2 QG D09 HQP NM_ ERCC3 QG D10 HQP NM_ EGF QG D11 HQP NM_ DNASE1 QG D12 HQP NM_ DMBT1 QG E01 HQP NM_ DHFR QG E02 HQP NM_ ACE QG E03 HQP NM_ ADRB2 QG E04 HQP NM_ CTNNB1 QG E05 HQP NM_ CREBBP

9 9 QG E06 HQP NM_ CCR5 QG E07 HQP NM_ AKAP13 QG E08 HQP NM_ RASSF1 QG E09 HQP NM_ PPARGC1A QG E10 HQP NM_ CARM1 QG E11 HQP NM_ CDK6 QG E12 HQP NM_ TP73 QG F01 HQP NM_ NEUROD2 QG F02 HQP NM_ LUM QG F03 HQP NM_ GHSR QG F04 HQP NM_ GHRHR QG F05 HQP NM_ ABCC4 QG F06 HQP BC FGFR1 QG F07 HQP NM_ EXO1 QG F08 HQP NM_ SLC6A4 QG F09 HQP NM_ DMTF1 QG F10 HQP NM_ CDC34 QG F11 HQP NM_ CDC25A QG F12 HQP NM_ CDC20 QG G01 HQP NM_ SETDB1 QG G02 HQP NM_ EPM2AIP1 QG G03 HQP NM_ ELMO1 QG G04 HQP NM_ CDC2 QG G05 HQP NM_ SPOCK2 QG G06 HQP NM_ ESPL1 QG G07 HQP NM_ KLK4 QG G08 HQP NM_ SLC4A7 QG G09 HQP NM_ TBX4 QG G10 HQP NM_ ROCK2 QG G11 HQP NM_ C1orf38 QG G12 HQP NM_ CHST3 QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR QG A01 HQP NM_ NRXN2 QG A02 HQP NM_ KL QG A03 HQP NM_ ITGB1BP1 QG A04 HQP NM_ CD4 QG A05 HQP NM_ BUB3

10 10 QG A06 HQP NM_ NMI QG A07 HQP NM_ VNN2 QG A08 HQP NM_ PCAF QG A09 HQP NM_ NRP1 QG A10 HQP NM_ NRP2 QG A11 HQP NM_ CES2 QG A12 HQP NM_ TNFRSF10A QG B01 HQP NM_ TNFRSF10B QG B02 HQP NM_ TNFSF10 QG B03 HQP NM_ RIPK1 QG B04 HQP NM_ TNKS QG B05 HQP NM_ CAV1 QG B06 HQP NM_ CNTNAP4 QG B07 HQP NM_ LMO4 QG B08 HQP NM_ CNTNAP1 QG B09 HQP NM_ FBXL20 QG B10 HQP NM_ KLF11 QG B11 HQP NM_ RECK QG B12 HQP NM_ CCDC98 QG C01 HQP NM_ AXIN2 QG C02 HQP NM_ AXIN1 QG C03 HQP NM_ NRIP1 QG C04 HQP NM_ CDT1 QG C05 HQP NM_ DPF3 QG C06 HQP NM_ CLPTM1L QG C07 HQP NM_ ACAD10 QG C08 HQP NM_ TNKS2 QG C09 HQP NM_ COASY QG C10 HQP NM_ CALCR QG C11 HQP NM_ EHMT1 QG C12 HQP NM_ SHFM1 QG D01 HQP NM_ VTCN1 QG D02 HQP NM_ ADIPOR2 QG D03 HQP NM_ CXCR4 QG D04 HQP NM_ PRDM2 QG D05 HQP NM_ WEE1 QG D06 HQP NM_ VHL QG D07 HQP NM_ USP1 QG D08 HQP NM_ UQCRFS1 QG D09 HQP NM_ UCP2 QG D10 HQP NM_ UBE2I QG D11 HQP NM_ TWIST1 QG D12 HQP NM_ TSHR QG E01 HQP NM_ TP53BP1 QG E02 HQP NM_ TNFRSF1B QG E03 HQP NM_ TLR3 QG E04 HQP NM_ TGFB2 QG E05 HQP NM_ TFR2

11 11 QG E06 HQP NM_ BUB1 QG E07 HQP NM_ TBXAS1 QG E08 HQP NM_ TBX2 QG E09 HQP NM_ TBP QG E10 HQP NM_ ADAM17 QG E11 HQP NM_ STAT3 QG E12 HQP NM_ STAT1 QG F01 HQP NM_ SSTR5 QG F02 HQP NM_ SSTR3 QG F03 HQP NM_ SREBF1 QG F04 HQP NM_ SRD5A1 QG F05 HQP NM_ SMARCA2 QG F06 HQP NM_ SLC20A1 QG F07 HQP NM_ SLC19A1 QG F08 HQP NM_ NOD2 QG F09 HQP NM_ BHMT QG F10 HQP NM_ CCL1 QG F11 HQP NM_ RPS6KA1 QG F12 HQP NM_ MRPL23 QG G01 HQP NM_ RPA3 QG G02 HQP NM_ RPA2 QG G03 HQP NM_ RPA1 QG G04 HQP NM_ ACTB QG G05 HQP NM_ REV3L QG G06 HQP NM_ RELA QG G07 HQP NM_ RBBP8 QG G08 HQP NM_ RAD17 QG G09 HQP NM_ RAD1 QG G10 HQP NM_ PTPRN2 QG G11 HQP NM_ LSM2 QG G12 HQP NM_ CALCOCO1 QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR QG A01 HQP NM_ MYH7B QG A02 HQP NM_ MTUS1 QG A03 HQP NM_ MTA3 QG A04 HQP NM_ PTHLH QG A05 HQP NM_ PTCH1

12 12 QG A06 HQP NM_ BCCIP QG A07 HQP NM_ TEX14 QG A08 HQP NM_ MAPK9 QG A09 HQP NM_ MAPK8 QG A10 HQP NM_ PRKCA QG A11 HQP NM_ IL17RB QG A12 HQP NM_ PPP2R5E QG B01 HQP NM_ PPP2R2A QG B02 HQP NM_ PPP2R1B QG B03 HQP NM_ ZWILCH QG B04 HQP NM_ PPP1CB QG B05 HQP NM_ ATRX QG B06 HQP NM_ PPARA QG B07 HQP NM_ UGT1A6 QG B08 HQP NM_ TERF2IP QG B09 HQP NM_ POLB QG B10 HQP NM_ SEPT4 QG B11 HQP NM_ TLR9 QG B12 HQP NM_ PNMT QG C01 HQP NM_ PLK1 QG C02 HQP NM_ PIK3CB QG C03 HQP NM_ PGC QG C04 HQP NM_ CRKRS QG C05 HQP NM_ UIMC1 QG C06 HQP NM_ HSD17B7 QG C07 HQP NM_ REV1 QG C08 HQP NM_ TUBD1 QG C09 HQP NM_ SLC45A2 QG C10 HQP NM_ HSD17B12 QG C11 HQP NM_ PCNA QG C12 HQP NM_ SH3GLB1 QG D01 HQP NM_ MLXIPL QG D02 HQP NM_ GMNN QG D03 HQP NM_ ODC1 QG D04 HQP NM_ NFKB1 QG D05 HQP NM_ NEK2 QG D06 HQP NM_ NCF4 QG D07 HQP NM_ NCF2 QG D08 HQP NM_ MYT1 QG D09 HQP NM_ MSH3 QG D10 HQP NM_ MSH2 QG D11 HQP NM_ MPG QG D12 HQP NM_ MMP12 QG E01 HQP NM_ KITLG QG E02 HQP NM_ MDM4 QG E03 HQP NM_ MBP QG E04 HQP NM_ MAT2A QG E05 HQP NM_ SMAD7

13 13 QG E06 HQP NM_ LRP1 QG E07 HQP NM_ LPL QG E08 HQP NM_ RHOC QG E09 HQP NM_ YPEL2 QG E10 HQP NM_ KPNB1 QG E11 HQP NM_ KLKB1 QG E12 HQP NM_ KISS1 QG F01 HQP NM_ JUN QG F02 HQP NM_ ITGB5 QG F03 HQP NM_ ITGAV QG F04 HQP NM_ ITGA6 QG F05 HQP NM_ INSR QG F06 HQP NM_ INS QG F07 HQP NM_ IL18 QG F08 HQP NM_ IL13 QG F09 HQP NM_ IL12RB2 QG F10 HQP NM_ IL4 QG F11 HQP NM_ IGHMBP2 QG F12 HQP NM_ IGFBP7 QG G01 HQP NM_ IGFBP5 QG G02 HQP NM_ IGFBP2 QG G03 HQP NM_ IGF2 QG G04 HQP NM_ HUS1 QG G05 HQP NM_ HTR3A QG G06 HQP NM_ HSD11B1 QG G07 HQP NM_ HSD3B1 QG G08 HQP NM_ PRMT1 QG G09 HQP NM_ HP QG G10 HQP NM_ FOXA1 QG G11 HQP NM_ HMMR QG G12 HQP NM_ HLA-A QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR QG A01 HQP NM_ HGF QG A02 HQP NM_ SLC40A1 QG A03 HQP NM_ GZMB QG A04 HQP NM_ GTF2E1 QG A05 HQP NM_ GTF2A1

14 14 QG A06 HQP NM_ GSK3B QG A07 HQP NM_ GRIK1 QG A08 HQP NM_ GPC1 QG A09 HQP NM_ GP1BA QG A10 HQP NM_ GNRHR QG A11 HQP NM_ GNAS QG A12 HQP NM_ GLG1 QG B01 HQP NM_ PELP1 QG B02 HQP NM_ STEAP1 QG B03 HQP NM_ AATF QG B04 HQP NM_ EHF QG B05 HQP NM_ RAD54B QG B06 HQP NM_ ALOX5AP QG B07 HQP NM_ PLD3 QG B08 HQP NM_ FN1 QG B09 HQP NM_ RRP1B QG B10 HQP NM_ CD93 QG B11 HQP NM_ PPM1E QG B12 HQP NM_ RRAS2 QG C01 HQP NM_ FEN1 QG C02 HQP NM_ FCGR2B QG C03 HQP NM_ FCGR2A QG C04 HQP NM_ FCER1A QG C05 HQP NM_ FBN1 QG C06 HQP NM_ FASN QG C07 HQP NM_ ALDH2 QG C08 HQP NM_ FANCA QG C09 HQP NM_ ESRRG QG C10 HQP NM_ AKT1 QG C11 HQP NM_ ABCA1 QG C12 HQP NM_ E2F2 QG D01 HQP NM_ AGT QG D02 HQP NM_ DRD2 QG D03 HQP NM_ ADAMTS18 QG D04 HQP NM_ HTR3C QG D05 HQP NM_ DHX9 QG D06 HQP NM_ DCN QG D07 HQP NM_ CYP24A1 QG D08 HQP NM_ CYP2E1 QG D09 HQP NM_ ADRB3 QG D10 HQP NM_ CYP2C8 QG D11 HQP NM_ BTLA QG D12 HQP NM_ IL23R QG E01 HQP NM_ CSTF1 QG E02 HQP NM_ CSNK1E QG E03 HQP NM_ CSNK1D QG E04 HQP NM_ CWF19L2 QG E05 HQP NM_ CRY2

15 QG E06 HQP NM_ JMY QG E07 HQP NM_ GIPC3 QG E08 HQP NM_ ADH1A QG E09 HQP NM_ CCR7 QG E10 HQP NM_ MMP21 QG E11 HQP NM_ AKAP10 QG E12 HQP NM_ IRAK3 QG F01 HQP NM_ YWHAQ QG F02 HQP NM_ STIP1 QG F03 HQP NM_ EHMT2 QG F04 HQP NM_ MAGED2 QG F05 HQP NM_ PPP1R13L QG F06 HQP NM_ ALDH1L1 QG F07 HQP NM_ CTCF QG F08 HQP NM_ POSTN QG F09 HQP NM_ CENPE QG F10 HQP NM_ HOXB13 QG F11 HQP NM_ MAD2L2 QG F12 HQP NM_ TOMM40 QG G01 HQP NM_ EMG1 QG G02 HQP NM_ CDK7 QG G03 HQP NM_ AKAP9 QG G04 HQP NM_ MUC6 QG G05 HQP NM_ DIRAS3 QG G06 HQP NM_ SHARPIN QG G07 HQP NM_ TPMT QG G08 HQP NM_ SSTR4 QG G09 HQP NM_ SSTR1 QG G10 HQP NM_ KLK10 QG G11 HQP NM_ POU1F1 QG G12 HQP NM_ NOS1 QG H01 HGDC QG H02 HGDC QG H03 HQP NM_ GAPDH QG H04 HQP NM_ ACTB QG H05 HQP NM_ B2M QG H06 HQP NM_ RPL13A QG H07 HQP NM_ HPRT1 QG H08 HQP NR_ RN18S1 QG H09 RT QG H10 RT QG H11 PCR QG H12 PCR 15

16 Limited Use License Following terms and conditions apply to use of ExProfile TM Breast Cancer Gene qpcr Array (the Product). If the terms and conditions are not acceptable, the Product in its entirety must be returned to GeneCopoeia within 5 calendar days. A limited End- User license is granted to the purchaser of the Product. The Product shall be used by the purchaser for internal research purposes only. The Product is expressly not designed, intended, or warranted for use in humans or for therapeutic or diagnostic use. The Product must not be resold, repackaged or modified for resale, or used to manufacture commercial products or deliver information obtained in service without prior written consent from GeneCopoeia. This Product should be used in accordance with the NIH guidelines developed for recombinant DNA and genetic research. Use of any part of the Product constitutes acceptance of the above terms. Limited Warranty GeneCopoeia warrants that the Product meets the specifications described in the accompanying Product Datasheet. If it is proven to the satisfaction of GeneCopoeia that the Product fails to meet these specifications, GeneCopoeia will replace the Product. In the event a replacement cannot be provided, GeneCopoeia will provide the purchaser with a refund. This limited warranty shall not extend to anyone other than the original purchaser of the Product. Notice of nonconforming products must be made to GeneCopoeia within 30 days of receipt of the Product. GeneCopoeia s liability is expressly limited to replacement of Product or a refund limited to the actual purchase price. GeneCopoeia s liability does not extend to any damages arising from use or improper use of the Product, or losses associated with the use of additional materials or reagents. This limited warranty is the sole and exclusive warranty. GeneCopoeia does not provide any other warranties of any kind, expressed or implied, including the merchantability or fitness of the Product for a particular purpose. GeneCopoeia is committed to providing our customers with high-quality products. If you should have any questions or concerns about any GeneCopoeia products, please contact us at GeneCopoeia, Inc. GeneCopoeia, Inc Medical Center Drive, Suite 101 Rockville, MD (301) (866) inquiry@genecopoeia.com GeneCopoeia Products are for Research Use Only Copyright 2016 GeneCopoeia, Inc. Trademarks: GeneCopoeia, ExProfile, All-in-One, (GeneCopoeia Inc.); RNAzol RT (Molecular Research Center, Inc.); SYBR (Molecular Probes); icycler iq, MyiQ, iq 5, CFX96, DNA Engine Opticon, DNA Engine Opticon 2, Chromo4 (Bio-Rad); LightCycler (Roche);Trizol, ABI,ROX,ViiA TM,StepOnePlus TM (Life Technologies). QG