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Prior January 2016 Authorization What Is Prior Authorization? It s a quality and safety program that promotes the proper use of certain medications. If your doctor prescribes a medication that is included in our Prior Authorization program, you must get prior approval before your plan will cover your medication. Please Note: Not all benefit plans include prior authorization. Check your plan materials to see if this information applies to you. We base the Prior Authorization program on U.S. Food and Drug Administration and manufacturer guidelines, medical literature, safety, accepted medical practice, appropriate use and benefit design. Prior Authorization only affects the medication that your benefit plan covers. You and your doctor should make the final decision about the medication that is right for you. Which Medications Are Included? This list includes both specialty and non-specialty drugs that require prior authorization. You will also find information on where your doctor should send a request for prior authorization. What Are the Possible Outcomes of a Prior Authorization Request? If you meet the requirements, your drug will be approved and we will cover it under your pharmacy benefits. Your drug may be approved for up to one year or more. You will be sent a letter letting you know that your drug has been approved. What Happens at a Retail Pharmacy? The pharmacist enters your prescription information into the computer system. If your medication needs prior authorization and you already have it, the pharmacist will fill your prescription. If you do not have prior authorization, you have three choices: You or your pharmacist can call your doctor and get a prescription for a different medication that does not need prior authorization. You can pay full price for your medication. You or your pharmacist can ask your doctor to get prior authorization for you. If you do not meet the requirements for prior authorization, you can still choose another option. If you submit your prescription to your plan s mail-order pharmacy and do not get prior authorization, the pharmacy will not fill your prescription. You will receive notification by mail. What Happens at a Specialty Pharmacy? Usually, your doctor will call or fax a prescription directly to the specialty pharmacy. If your prescription requires prior authorization, the specialty pharmacy will tell your doctor how to request this. If you do not meet the requirements, your prior authorization will be denied. Also, if your doctor does not send in the requested information within a certain period of time, your prior authorization will be denied. If your request is denied, both you and your doctor will be sent a letter explaining the denial. The letter will include information about how you can appeal the decision.

Specialty Drug Prior Authorization List Requests for specialty drug prior authorizations go to CVS/specialty TM at 800-237-2767 (phone) or 866-249-6155 (fax). CVS/specialty is a division of CVS Caremark, an independent company that provides pharmacy services on behalf of your health plan. Abraxane Actemra + Acthar HP Actimmune NF Adagen Adectris Adcirca Adempas Advate Afinitor Aldurazyme Alferon-N Alimta Alphanate AlphaNine SD Alprolix Ampyra Apokyn Aralast NP Aranesp Arcalyst Arzerra Aubagio + Avastin Aveed Avonex + Azacitidine Bebulin VH Beleodaq BeneFIX Benlysta Berinert Betaseron Bethkis Bivigam Blincyto Bosulif Botox Bravelle + Buphenyl capecitabane (generic Xeloda) Caprelsa Carbaglu Carimune NF Cayston Ceprotin Cerdelga Cerezyme Cetrotide Cholbam Chorionic gonadotropin Cimzia + Cinryze Cometriq Copaxone Copegus Corifact Cosentyx + Cyramza Cystagon Cystaran Cytogam Dacogen Decitabine Deferoxamine Desferal Duopa Dysport Egrifta Elaprase Elelyso Eligard Eloctate Eloxatin Enbrel Entyvio + Epogen Epoprostenol (Flolan) Erbitux Erivedge Erwinaze Esbriet Euflexxa + Exjade Extavia + Eylea Fabrazyme Farydak Feiba NF Ferriprox Firazyr Firmagon Flebogamma Follistim AQ + Folotyn Forteo Fusilev Fuzeon Gamastan S/D Gammagard Gammagard S/D Gammaked Gammaplex Gamunex C Ganirelix Gattex Gazyva Gel-One Gemzar Genotropin + Gilenya Gilotrif Glassia Glatopa Gleevec Gonal-F Granix Grastek Halaven Helixate FS Hemofil M Herceptin Hetlioz Hizentra Humate-P Humatrope Humira Hyalgan Hycamtin HyQvia Ibrance Iclusig Ilaris Illuvien Imbruvica Incivek Increlex Inlyta Intron-A Iressa Istodax Ixempra Ixinity Jadenu Jakafi Jevtana Juxtapid Kadcyla Kalbitor Kalydeco Keytruda Kineret + Kitabis Pak Koate-DVI Kogenate FS Korlym Krystexxa Kuvan Kynamro Kyprolis Lemtrada Lenvima Letairis Leukine Leuprolide Lonsurf Lucentis Lupaneta Lupron Depot Lumizyme Lynparza Macugen Mekinist Menopur Mircera Mitoxantrone Monoclate-P Mononine Monovisc + Mozobil Myalept Myobloc Myozyme Naglazyme Natpara Neulasta Neumega Neupogen Nexavar Norditropin Northera Novoeight Novoseven Nplate Nutropin AQ + Obizur Octagam Octreotide Acetate Odomzo Ofev Olysio + Omnitrope + Oncaspar Opdivo Opsumit Oralair Orencia + Orenitram Orfadin Orkambi Orthovisc + Otezla + Ovidrel Ozurdex Pegasys PEG-Intron Perjeta Plegridy + Pomalyst Prialt Privigen Procrit Procysbi Profilnine SD Prolastin-C Proleukin Prolia Promacta Provenge Pulmozyme Ragwitek Ravicti Rebetol Rebif Rebif Rebidose Reclast Recombinate Regranex Remicade + Remodulin Repronex Retisert Revlimid RiaSTAP Ribapak Ribasphere Ribavirin Rituxan + Rixubis Ruconest Sabril Saizen + Samsca Sandostatin Sandostatin LAR Sensipar Serostim Signifor LAR Sildenafil (Revatio) Simponi + Simponi Aria + Soliris Somatuline Depot Somavert Sovaldi + Sprycel Stelara + Stimate Stivarga Supartz Supprelin LA Sutent Sylatron Sylvant 2

Synagis Synribo Synvisc + Synvisc One + Taflinar Tarceva Targretin Tasigna Tecfidera Temodar Temozolomide Thalomid Tikosyn TOBI Podhaler Tobramycin inhalation solution Torisel Tracleer Treanda Trelstar Depot Tretten Tykerb Tysabri + Tyvaso Unituxin Valchlor Valstar Vandetanib Vantas Vectibix Velcade Veletri Ventavis Vidaza Viekira Pak Vimizim Visudyne Votrient Vivitrol VPRIV Wilate Xalkori Xeljanz + Xeloda Xenazine Xeomin Xgeva Xiaflex Xolair Xtandi Xyntha Xyrem Yervoy Zaltrap Zarxio Zavesca Zecuity Zelboraf Zemaira Zoladex Zoledronic acid Zolinza Zomacton + Zometa Zorbtive Zydelig Zykadia Zytiga Preferred specialty drugs are listed in bold. + Medical Necessity Prior Authorization required. Before coverage for this drug, you must try at least one other drug first. See Table A for more information. Non-Specialty Drug Prior Authorization List Requests for prior authorization go to Caremark at 800-294-5979 (phone) or 888-836-0730 (fax). Please note that compound drugs with a cost of $300 or more require prior authorization. Abstral Actiq Advicor + Altoprev + Ambien + Ambien CR + Amitiza + Amrix + Anadrol-50 Androgel + Apidra + Atacand + Atacand HCT + Atralin Avalide + Avapro + Avita Beconase AQ + Belsomra + Bunavail + Buprenorphine Byetta + Celebrex Cozaar + Crestor + Detrol + Detrol LA + Diovan + Diovan HCT + Differin Ditropan XL + Duexis + Dulera + Dymista + Edarbi + Edarbyclor + Edluar + Epanova Evekeo Fabior Fentora Flonase + Fortamet + Fortesta + Glumetza + Gralise Humalog + Humulin + (except U-500) Hyzaar + Intermezzo + Invokana + Invokamet + Jentadueto + Kazano + Lazanda Lescol + Lescol XL + Levemir + Lipitor + Liptruzet + Livalo + Lotronex Lovaza Lumigan + Lunesta + Mevacor + Micardis + Micardis HCT + Myrbetriq + Naprelan + Nasacort AQ + Natesto + Nesina + Nexium + Nuvigil Oleptro + Olux-E + Omnaris + Onmel Omtryg Onsolis Oseni + Oxandrin Oxytrol + Pennsaid + Pravachol + Provigil Qnasl + Rayos + Retin A Rhinocort Aqua + Riomet + Sanctura + Silenor + Sonata + Soriatane Sporanox Oral Capsules Sporanox Oral Solution Sprix + Suboxone Subutex Subsys Tanzeum + Tazorac Tekturna + Tekturna HCT + Test Strips (all but OneTouch) + Testim + Teveten + Teveten HCT + Toujeo + Toviaz + Tradjenta + Tretin-X Trulicity + Vascepa Veltin Veramyst + Vimovo + Vogelxo + Vytorin + Zetonna + Ziana Zipsor + Zocor + Zohydro Zolpimist + Zorvolex + Zubsolv + + Medical Necessity Prior Authorization required. Before coverage for this drug, you must try at least one other drug first. See Table B for more information. 3

Table A. Specialty Drugs Medical Necessity Prior Authorization Growth Deficiency Before you have coverage for one of these drugs Genotropin, Nutropin AQ, Omnitrope, Saizen, Zomacton you must have tried one (or more) of these alternative drugs first. Humatrope, Norditropin Hepatitis C (Direct Acting Antivirals) Olysio, Sovaldi Viekira Pak Infertility Bravelle, Follistim AQ Gonal-F (all) Inflammatory s Crohn s Disease, Psoriasis, Rheumatoid Arthritis Multiple Sclerosis Osteoarthritis of the Knee Actemra, Cimzia, Cosentyx, Entyvio, Kineret, Orencia, Otezla, Remicade, Rituxan, Simponi, Simponi Aria, Stelara, Xeljanz Aubagio, Avonex, Extavia, Plegridy, Tysabri Euflexxa, Monovisc, Orthovisc, Synvisc, Synvisc One Enbrel and Humira Betaseron, Copaxone, Gilenya, Glatopa, Rebif, Tecfidera Gel-One, Hyalgan, Supartz Table B. Non-specialty Drugs Medical Necessity Prior Authorization Arthritis/Pain Before you have coverage for one of these drugs Naprelan, Pennsaid, Sprix, Zipsor, Zorvolex Duexis, Vimovo you must have tried at least one of these alternative drugs first. generic NSAIDs generic NSAID and generic PPIs Asthma/COPD Dulera Advair, Symbicort (high potency) Crestor, Liptruzet, Vytorin atorvastatin Advicor atorvastatin, fluvastatin, lovastatin, pravastatin, Simcor, simvastatin Altoprev, Lescol/XL, Lipitor, Livalo, Mevacor, Pravachol, Zocor atorvastatin, fluvastatin, lovastatin, pravastatin, simvastatin Corticosteroids Rayos Immediate-release generic prednisone Depression Oleptro trazodone Dermatologic Olux-E Clobetasol propionate foam 0.05% Diabetes (Insulin) All Apidra, Humalog and Humulin (except U-500) Novolog, Novolin Diabetes (long-acting insulin) Levemir, Toujeo Lantus Diabetes (Biquanides) Fortamet, Glumetza, Riomet metformin/xr Diabetes (DPP-4) Kazano, Nesina, Oseni, Tradjenta, Jentadueto Januvia, Janumet, Janumet XR, Onglyza, Kombiglyze continued 4

Table B. Non-specialty Drugs Medical Necessity Prior Authorization Before you have coverage for one of these drugs you must have tried at least one of these alternative drugs first. Diabetes (SGLT2) Invokana, Invokamet Farxiga, Jardiance, Synjardy, Xigduo XR Diabetes (GLP-1) Byetta, Tanzeum, Trulicity Bydureon, Victoza Diabetes Supplies All test strips other than One Touch * OneTouch Glaucoma Lumigan lantanoprost, travoprost, Travatan Z, Zioptan Heartburn or Acid Reflux Hypertension Nexium Atacand/HCT, Avapro, Avalide, Cozaar, Hyzaar, Diovan/HCT, Edarbi, Edarbyclor, Micardis/HCT, Tekturna/HCT, Teveten/HCT Nexium 24HR (OTC) and one of these prescription generics: esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole generic ARBs, Benicar/HCT Irritable Bowel Syndrome Amitiza Linzess Muscle Relaxants Amrix cyclobenzaprine Nasal Steroids Beconase AQ, Dymista, Flonase, Nasacort AQ, Omnaris, Qnasl, Rhinocort AQ, Veramyst, Zetonna budesonide nasal spray, flunisolide, fluticasone nasal, Nasonex, triamcinolone Opioid Partial Agonists Bunavail, Zubsolv Suboxone Film, generic Suboxone Detrol/LA, Ditropan XL, Myrbetriq, oxybutynin ext-rel, tolterodine, tolterodine extrel, trospium, trospium ext-rel, Gelnique, Overactive Bladder Oyxtrol, Toviaz Vesicare Sleep Medications Testosterone Replacement Ambien, Ambien CR, Belsomra, Edluar, Intermezzo, Lunesta, Silenor, Sonata or Zolpimist Androgel, Fortesta, Natesto, Testim, Vogelxo eszopiclone, zolpidem, zolpidem ext-rel, zaleplon Androderm, Axiron, testosterone gel (generic Fortesta) *Members on insulin pumps that require specific test strips other than OneTouch may be granted a lifetime approval to continue to fill their current test strips. Your benefit document defines actual benefits available and may exclude coverage for certain drugs listed here. Check your benefit information to verify coverage or view your personal benefit information on our website. This list may contain trademarks or registered trademarks of pharmaceutical manufacturers that are not affiliated with your health plan. This list may change or expand from time to time without prior notice. When we list brand-name drugs, programs may also apply to any available generic equivalents. 5