Peucedanum ruthenicum (M. Bieb.) Rochel 6 5 4 3 *2 85/5/25 : : * -2-4 -5-6 (02) 664678 : (02) 66959090 : yasa@sina.tums.ac.ir : 84/6/5 : :. :. 383 Peucedanum ruthenicum M. Bieb :.. GC GC/MS ). Agar-dilution Disk-diffusion (. ( 00) 7 :. ( 57/79) MIC :. MIC Peucedanum ruthenicum M.Bieb : 33 385 ( ) 48
.... (39 ) 200.. 0/3 v/w ( 2-8 ). GC GC/MS. GC/MS GC HP- 5 MS Hewlett Packard 6890 ( 0/25 30 ) 5973 70 ev 290 250 5 60 220 GC. 6..[7] HP- 5.( ) Wiley : [8] :Disk-diffusion ATCC 29737 ATCC 4990.[ 2] 00 20 Peucedanum.[3 4 5]..[6] 29 Peucedanum P. glaucopruinosum [8] P. Ruthenicum [7] P. Knappii P. translucen. [9] [0]. []. [2 3] P. ruthenicum ( ) ( ) ( ).[4] -4 ( 35/2) :. P. ostruthicum 5/8) ( 6/) ( 26/6) P. verticillare [5] (.[6] 383 (IZD: Inhibition Zone Diameter mm) Peuruthenicin 34
P. ruthenicum 00 0/3.. 7 58/47 57/79 0/68 38/74. 22/83 5/9 - ( 4/75) - ( 6/) ( 3/05) - ( 4/63) ( 5/4) ( 3/9) ( 4/63). : 39 P. ostruthium ( 5/8) - ( 6/) ( 4/4) ( 4/7) [5] ( 0/4) -. P. verticillare.[6] 73 P. scoparium 23/9) - ( 39/6) - : [2] ( 9/5) - (. P. ruthenicum ATCC 8739 ATCC 247 ATCC 9430 ATCC 9027. 0 (M-H) 9. 48 cfu/ml 0. (d= 0/8) 2 2/5 ( 6 3 ) 4.. 200 µg/disc 8 37 4 mm.(2 ) [9] [20] :Agar-dilution -2 2 (0/00 0/5) MIC DMSO 8 ) 37 DMSO.(3. (MICs: Minimum Inhibition Concentrations mg/ml) 35 385 ( )
... P. ruthenicum - a RRI Leaves% Compounds Name 0 0/ 58 n-decane 50 2/ 2 E-Nonenal 2 60 0/ 68 Borneol 3 294 57/ 79 Thymol 4 368 0/ 74 α-ylangene 5 425 3/ 6 Trans-Caryophylene 6 438 / 39 β-gurjunene 7 459 3/ 05 Trans-β-farnesene 8 476 4/ 75 α-amorphene 9 480 0/ 35 Germacrene D 0 503 6/ β-bisabolene 508 0/ 7 Gamma-cadinene 2 528 2/ 5 Delta-cadinene 3 584 4/ 63 Caryophyllene oxide 4 589 / 97 Salvial-4(4)-en-one 5 770 5/ 4 Lanceol 6 820 3/ 9 Hexahydrofarnesyl acetone 7 - Hydrocarbon monoterpenes 58/47 Oxygenated monoterpenes 22/83 Hydrocarbon sesquiterpenes 5/9 Oxygenated sesquiterpenes 2/79 Nonterpenes - Unknown 00 Total identified ª RRI: relative retention indices as determined on a HP-5 column using the homologous series of n-alkan P. ruthenicum - 2 a (n = 4) (Disk-diffusion) Inhibition Zone Diameter (IZD) mm Neomycin (200 µg) Essential oil (2 mg/disc) 2 3 a 6 3 7 9 23 34 6 6 8 S. aureus Strains S. epidermidis B. cereus E. coli P. aeroginosa S. typhi 36
P. ruthenicum - (Agar dilution) Minimum Inhibition Concentrations (MICs) mg/ml Neomycin mg/ml Essential oil mg/ml -2 4 /0 0 2 /0 0 /2 0 /2 0 2 /4 0 2 /3 0 4 /0 0. ( 57/79) [23 24].. /8 0-2 9 /0 0 2 / 0 4 /8 0 3 /6 0 S. aureus. Czygan FC. Kulturgeschichte und Mystik des Johanniskrautes. Zeitschrift für phytotherapie 993; 5: 276-282. 2. Ody P. The complete medicinal herbal. New York. Dorling Kindersley limited 993, pp. 70-7. 3. Hölzl j. Inhaltstoffe und wirkmechanismen des Johanniskrautes. Z.Phytotherapie 993; 5: 255-264. 4. Öztürk Y, Aydin S, Başer KHC, Öztürk N. 3 Strains S. epidermidis B. cereus E. coli P. aeroginosa S. typhi 73/9 P. cervariifolium P. ruthenicum - -.[22]. P. ruthenicum P. ruthenicum Hypericum perforatum L. bitkisinin siçanlarda koleretik aktivitesi. IX. Bitkisel Ilaç Hammaddeleri Toplantisi Bildiri Kitabi. Anadolu Üniversitesi. Eskişehir 992, p. 26. 5. Maisenbacher J. Schmidt U, Schenk N. Therapie mit Hypericum beiangstzustanden. TW. Neurol. Psychiatrie 995; 9: 65-70. 6. Tutin TG, Heiwood VH, Barges NA, Moore. DM, Valentine DH, Walters SM, Webb DA. Flora Europaen. The University Press, Cambridge 968; 37 385 ( )
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