Corynebacterium kroppenstedtii

HTML
DOWNLOAD

Μέγεθος: px

Εμφάνιση ξεκινά από τη σελίδα:

Download "Corynebacterium kroppenstedtii"

Ιολανθη Κορομηλάς
8 χρόνια πριν
Προβολές:

1 2012 C. kroppenstedtii Corynebacterium kroppenstedtii flomoxef, clindamycin 5 BD Corynebacterium kroppenstedtii C. kroppenstedtii C. kroppenstedtii Key words: Corynebacterium kroppenstedtii, mastitis, lipophilic corynebacteria 2 10 Staphylococcus aureus coagulase negative staphylococci viridans streptococci 1 Corynebacterium kroppenstedtii C. kroppenstedtii TEL: FAX: sugayo@ngt.ndu.ac.jp cefcapene pivoxil CFPN-PI Fig /μl CRP 7.36 mg/dl 33 mm 17 mm Vol. 22 No

2 162 Fig. 1. Clinical course. CFPN-PI: cefcapene pivoxil, FMOX: flomoxef, CLDM: clindamycin, LVFX: levofloxacin, MEPM: meropenem, CEZ: cefazorin, BT: Body temperature, WBC: White blood cell count, CRP: C-reactive-protein Fig. 2. Ultrasonograph. A: 1/11. A hypoechoic lesion measuring 33 mm 17 mm with abscess was observed in the right breast.b: 1/11. multifolicular abscess formation. C: 1/ mm 20mm with abscess. D: 1/14. Reduction of abscess. E: 1/ mm 20 mm with abscess. F: 1/ mm with abscess. Fig. 2A, B 3 12 ml flomoxef FMOX 1 g 2/day clindamy cin CLDM 600 mg 2/day Fig levofloxacin LVFX 100 mg 6/day Vol. 22 No

3 C. kroppenstedtii mm Fig. 2E meropenem MEPM 0.5 g 2/day CLDM 150 mg 4/day, CFPN-PI 100 mg 3/day , 16, BD GAM Api Coryne Corynebacterium argentoratense No , S rrna C. kroppenstedtii DDBJ accession number; CP % 1446/1451 C. kroppenstedtii 2 23 C. kroppenstedtii 1 Tween MIC Clinical Laboratory Standard Institute CLSI document M45-A MIC Table 1 C. kroppenstedtii Tween80 1Tween CLSI Table Fig. 3 C. kroppenstedtii 1998 Collins 9 C. kroppenstedtii annotation 10 C. kroppenstedtii C. kroppenstedtii Vol. 22 No

4 164 Table 1. Comparison of antibiotic susceptibility with Brucella broth and CAMHB added Tween80 Burucella broth CAMHB added Tween80 Incubation time 24 h 48 h 24 h 48 h MIC μg/ml) MIC μg/ml) MIC μg/ml) MIC μg/ml) MPIPC ABPC CEZ FMOX IPM GM MINO EM CLDM VCM TEIC FOM >128 >128 >128 >128 LVFX CAMHB: Cation-adjusted Mueller-Hinton broth MPIPC: oxacillin, ABPC: ampicillin, CEZ: cefazolin, FMOX: flomoxef, IPM: imipenem, GM: gentamicin, MINO: minocycline, EM: erythromycin, CLDM: clindamycin, VCM: vancomycin, TEIC: teicoplanin, FOM: fosfomycin, LVFX: levofloxacin Fig. 3. Histopathology biopsy revealed inflammation with a major presence of lymphocytes and macrophages hematoxylin eosin stain; original magnification, 100. C. kroppenstedtii 2 6 C. kroppenstedtii 21 Table Vol. 22 No

5 C. kroppenstedtii Table 2. References of cases of mastitis isolated Corynebacterium kroppenstedtii Year Age Specimen Histological findings Reference abscess 12) pus swab no granulomas 2) granulomas 2) pus GLM 2) aspirated pus no granulomas 2) aspirated pus 2) pus 2) tissue lipogranulomas 2) pus GLM with suppurative lipogranulomas 2) pus 2) pus 2) aspirated pus suppurative lipogranulomas 2) aspirated pus no granulomas 2) pus swab GLM with suppurative lipogranulomas 2) granuloma 3) no granulomas 3) aspirated pus mass 4) puncture granulaomatous mastitis 5) pus granulaomatous mastitis 6) granulaomatous mastitis 11) abscess no granulomas Present case GLM: granulomatous mastitis 11 5 C. kroppenstedtii 2 C. kroppenstedtii C. kroppenstedtii Riegel Trypticase Soy 1 Tween80 24 Tween80 CLSI document M45-A 8 48 MIC Tween80 24 MIC Tween β- C. kroppenstedtii C. kroppenstedtii β- 2 MEPM 0.5 g 2/day 3 g/day C. kroppenstedtii Vol. 22 No

6 C. kroppenstedtii : Paviour, S., S. Musaad, S. Roberts, et al Corynebacterium species isolated from patients with mastitis. Clin. Infectious Diseases 35: Taylor, G. B., S. D. Paviour, S. Musaad, et al A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology 35: Riegel, P., P. Liegeois, M. P. Chenard, et al Isolations of Corynebacterium kroppenstedtii from a breast abscess. Int. J. Med. Microbiol. 294: Kieffer, P., R. Dukic, M. Hueber, et al A young woman with granulomatous mastitis: A corynebacteria may be involved in the pathogenesis of these disease. Rev. Med. Interne. 27: Corynebacterium kroppenstedtii 1 69: Riegel, P., R. Ruimy, D. D. Briel, et al Corynebacterium argentoratense sp. nov., from the human throat. Int. J. Syst. Bacteriol. 45: Clinical and Laboratory Standards Institute Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria, approved guideline CLSI document M45- A. Clinical and Laboratory Standards Institute, Wayne, Pa. 9 Collins, M. D., E. Falsen, E. Akervall, et al Corynebacterium kroppenstedtii sp. nov., a novel corynebacterium that does not contain mycolic acids. Int. J. Syst Bacteriol. 48: Tauch, A., J. Schneider, R. Szczepanowski, et al Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids. J. Biotechnol. 136: Beatrice, B., K. Caroline, O. Claire, et al First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. J. Clin. Microbiol. 47: Bernard, K. A., C. Munro, D. Wiebe, et al Characteristics of rare or recently described corynebacterium species recovered from human clinical material in Canada. J. Clin. Microbiol. 40: A Case of Recurrent Mastitis Caused by Corynebacterium kroppenstedtii Yoshiaki Sugahara 1, Kiyofumi Ohkusu 2, Yoshihito Ohtsuka 3 Eiko Sakata 4, Takeyasu Suda 5 Masataka Nakae 1, Koichi Sibasaki 6 1 Department of Clinical Laboratory Medical Hospital, The Nippon Dental University School of Life Dentistry at Niigata 2 Department of Microbiology Regeneration and Advanced Medical Science, Gifu University Graduate School of Medicine 3 Devision of Clinical Laboratory, Kameda General Hospital 4 Devision of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences 5 Department of Surgery Medical Hospital, The Nippon Dental University School of Life Dentistry at Niigata 6 Department of Internal Medicine Medical Hospital, The Nippon Dental University School of Life Dentistry at Niigata We report a 36-year-old woman with an abscess of her right breast whose primary complains were breast pain and fever. Gram staining revealed Gram-positive rods eated polymorphonuclear leukocytes. The specimen of abscess was cultured at 35, on the second day colonies formed which appeared white,nonhemolytic in the blood agar. The biochemical profile of the isolate was determined by the API Coryne system,but was not recognized by the database.comparative 16S rrna gene sequence analysis demonstrated the strains represent within the species Corynebacterium kroppenstedtii. C. kroppenstedtii is characterized by lipophilic corynebacteria. They grew well on Trypticase Soy agar which contains 1%Tween80 in aerobic condition. We would propose that Gram staining and culture by Trypticase Soy agar added Tween80 is important in the clinical specimen with granulomatous mastitis and persistent mastitis. 62 Vol. 22 No

Σχετικά έγγραφα

c Key words: cultivation of blood, two-sets blood culture, detection rate of germ Vol. 18 No

c Key words: cultivation of blood, two-sets blood culture, detection rate of germ Vol. 18 No 2008 245 2 1) 1) 2) 3) 4) 1) 1) 1) 1) 1), 2) 1) 2) 3) / 4) 20 3 24 20 8 18 2001 2 2 2004 2 59.0 2002 1 2004 12 3 2 22.1 1 14.0 (CNS), Bacillus c 2 p 0.01 2 1 31.3 41.9 21.4 1 2 80 CNS 2 1 74.3 2 Key words: