45. 8% % % l 25% 5 5% % 125 I

Σχετικά έγγραφα
laparoscopically assisted distal gastrectomy 1

Octretide joint proton pump inhibitors in treating non-variceal gastrointestinal bleeding a Metaanalysis

10%~15% 7.28/10. [DOI] /j.issn

Ankylosing Spondylitis AS. NSAIDs. NSAIDs 100% B27 NSAID ~ 90% FDA EMA

Καρκίνος προστάτη σε ασθενείς ενδιάμεσου κινδύνου. Ριζική προστατεκτομή vs. Ακτινοθεραπεία

RFA : HCC. percutaneous acetic acid injection therapy: PAIT 3 percutaneous hot water injection therapy: PHot 4 HCC HCV HCC

Development of a new arterial infusion chemotherapy for locally advanced breast cancer

Vol. 36, pp , Stage I, II. Stage I, II cm

Δυσμενείς παράγοντες μετά ριζική προστατεκτομή. Μετεγχειρητική ακτινοθεραπεία ή ακτινοθεραπεία διάσωσης;

3. 1 CMV. GGT alkaline phosphatase ALP ALT AST. Vol. 6 No. 1 Jan Organ Transplantation. DOI /j.issn

R GHRP rh- GH

Accumulation of Soil Arsenic by Panax notoginseng and Its Associated Health Risk

Evaluation of the Efficacy of Olopatadine Hydrochloride in the Treating Allergic Rhinitis A Multicenter Randomized Double-blind Double-dummy Study

0. 35g kg ~ 2. 0cm 10min. Nar- 15μL 6mm

ΑΤΣΟΑΝΟΗ ΠΑΓΚΡΕΑΣΙΣΙΔΑ. ηέξγηνο Γειαθίδεο Γαζηξεληεξνιόγνο

(30%) [3 7] (VAS) Karnofsky Frankel. Karnofsky <60. [DOI] /j.issn

(intrauterine adhesion IUA) (Asherman syndrome) (transcervical resection of adhesions TCRA) 1988 (American Fertility Society

BGP TRACP-5b BGP TRACP-5b P 0.05

chronic kidney disease CKD A Survey and Analysis of Chinese Patent Medicine for Outpatients with Chronic Kidney Disease SU Guobin LIU

Peutz-Jeghers 71. Peutz-Jeghers Peutz-Jeghers syndrome PJS LKB1/STK11 PJS. Peutz-Jeghers PJS R656 R735 3 A

The Exploitation and Utilization of Magnesium Resources in Salt Lakes

Advance in Nanorealgar Studies

Chinese Clinical Oncology Nov Vol. 19 No. 11 B MALT

thrombolysis in myocardial infarction TIMI 5 /6 vs 3 /13 P < /30 vs 15 /30 P < 0.

Καρκίνος ορθού Προεγχειρητική ακτινοθεραπεία. Λουίζα Βίνη Ογκολόγος Ακτινοθεραπεύτρια Τμήμα Ακτινοθεραπείας Ιατρικό Αθηνών

Research on explaining porosity in carbonate reservoir by capture cross section method

Research on the Environmental Impact Factors of Electromagnetic Radiation from High - speed Railway

China Academic Journal Electronic Publishing House. All rights reserved.

3DVT DVT, PTA) DVT 2.3 PTA. 7 d

J. of Math. (PRC) Banach, , X = N(T ) R(T + ), Y = R(T ) N(T + ). Vol. 37 ( 2017 ) No. 5

ΣΤΑΔΙΟΠΟΙΗΣΗ ΚΑΡΚΙΝΟΥ ΠΝΕΥΜΟΝΑ ΕΚΤΙΜΗΣΗ ΑΝΑΤΟΜΙΚΗΣ ΕΚΤΑΣΗΣ ΝΟΣΟΥ

Αντιμετώπιση καρκίνου πνεύμονα με βάση τις Διεθνείς κατευθυντήριες Οδηγίες

Research on Economics and Management

Journal of Experimental Hematology

LUO, Hong2Qun LIU, Shao2Pu Ξ LI, Nian2Bing

Χημειοθεραπεία στο Χολαγγειοκαρκίνωμα Τι νεότερο?

καρκίνος στομάχου έχει θέση η ακτινοθεραπεία; Ιωάννης Γεωργακόπουλος Ακτινοθεραπευτής Ογκολόγος

Study on the Strengthen Method of Masonry Structure by Steel Truss for Collapse Prevention

Αντιμετώπιση του μεταστατικού καρκίνου του νεφρού

ΔΕΑ στην MDCT: Διεθνής βιβλιογραφία και τα πρώτα στοιχεία από την Ελλάδα

Gerard A. Silvestri, MD, FCCP; and M. Patricia Rivera, MD, FCCP NSCLC EGFR NSCLC EGFR EGFR NSCLC. (epidermal growth factor receptor);

IL - 13 /IL - 18 ELISA PCR RT - PCR. IL - 13 IL - 18 mrna. 13 IL - 18 mrna IL - 13 /IL Th1 /Th2

Relationship between Connective Tissue Diseases and Thyroid Diseases

ΙΩΑΝΝΗΣ Η. ΓΚΡΙΝΙΑΤΣΟΣ Αναπλ Καθηγητής Χειρουργικής ΕΚΠΑ. 1o Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Ήπατος-Χοληφόρων-Παγκρέατος

Ca P και οστικές μεταστάσεις

( ) , ) , ; kg 1) 80 % kg. Vol. 28,No. 1 Jan.,2006 RESOURCES SCIENCE : (2006) ,2 ,,,, ; ;

ΑΚΤΙΝΟΘΕΡΑΠΕΥΤΙΚΗ ΠΡΟΣΕΓΓΙΣΗ ΣΤΟΝ ΚΑΡΚΙΝΟ ΤΟΥ ΠΡΟΣΤΑΤΟΥ - ΠΟΤΕ?

Blood May 16;121(20): ΒΙΒΛΙΟΓΡΑΦΙΚΗ ΕΝΗΜΕΡΩΣΗ ΓΝΑ ΕΥΑΓΓΕΛΙΣΜΟΣ Θ. ΚΑΝΕΛΛΟΠΟΥΛΟΥ

Experimental Study of Dielectric Properties on Human Lung Tissue

The toxicity of three chitin synthesis inhibitors to Calliptamus italicus Othoptera Acridoidea

Η ΘΕΣΗ ΤΗΣ ΛΕΜΦΑ ΕΝΕΚΤΟΜΗΣ ΣΤΟ ΚΑΡΚΙΝΟ ΤΟΥ ΝΕΦΡΟΥ

Analysis on construction application of lager diameter pile foundation engineering in Guangdong coastal areas

Γαστρεντερο-Παγκρεατικά Νευροενδοκρινή Νεοπλάσματα grade 3 (GEP NEN G3) Νεότερα Παθολογοανατομικά Δεδομένα

Apr Vol.26 No.2. Pure and Applied Mathematics O157.5 A (2010) (d(u)d(v)) α, 1, (1969-),,.

Gro wth Properties of Typical Water Bloom Algae in Reclaimed Water

Analysis of energy consumption of telecommunications network and application of energy-saving techniques

Q L -BFGS. Method of Q through full waveform inversion based on L -BFGS algorithm. SUN Hui-qiu HAN Li-guo XU Yang-yang GAO Han ZHOU Yan ZHANG Pan

Studies on Synthesis and Biological Activities of 2( 1 H21,2,42 Triazol212yl)2 2Arylthioethyl Substituted Phenyl Ketones

Journal of Experimental Hematology ML AHSCT

ΣΥΓΓΕΝΗΣ ΑΟΡΤΟΠΑΘΕΙΕΣ: ΣΗΜΑΝΤΙΚΟΤΕΡΕΣ ΜΕΛΕΤΕΣ ΤΟΥ 2014

ΠΑΡΑΣΚΕΥΗ, 24 Οκτωβρίου Σεμινάριο: ΚΑΡΚΙΝΟΣ ΤΟΥ ΠΑΓΚΡΕΑΤΟΣ

-1 (MIC-1) 229 MIC-1, CEA CA125 NSE CYFRA21-1 SCC [ ] MIC-1 (P<0.001) MIC % 96.5% MIC-1 MIC-1 MIC-1. doi: /j.issn

Κάπνισμα στον Ελληνικό πληθυσμό. Εφαρμογή των νέων μέτρων απαγόρευσης, τρόποι διακοπής και καρδιολογική προσέγγιση

Quick algorithm f or computing core attribute

Rapid Raman spectra identification and determination of levofloxacin hydrochloride injection *

Βιοχημική υποτροπή σε ασθενή με καρκίνο του προστάτη:

TNF TNF Karnofsky [6] /L /L 90 g/l 1 >3. rmhtnf. rmhtnf. rmhtnf. rmhtnf [3-5] rmhtnf 400 U/m 2 CR.

Βασικές αρχές χηµειοθεραπείας στην αντιµετώπιση του µικροκυτταρικού καρκίνου (SCLC)

Πρωτοπαθές κακόηθες μελάνωμα ορθού: Ένας σπάνιος καρκίνος με κακή πρόγνωση

Third Term, Week April Hours Monday Tuesday Wednesday Thursday Friday. 3D-MIR (th) IA (lth) 3D_MI 3D_MI. 3D-MIS (th)

CK8 / % 63 /76 P < A doi /j. issn

Πρόγραμμα Ογκολογίας Ουροποιογεννητικού GenitoUrinary Oncology

Application of Statistical Process Control in Pretreatment Production Process of Gardenia jasminoides

Bisphosphonate. Bisphosphonate BP. Starck BP. BP Bisphosphonate Related Osteonecrosis of the Jaw : BRONJ BP ONJ BP P O P P C P + BRONJ BP BP BRONJ

Jeffrey J. Swigris, DO; Ware G. Kuschner, MD, FCCP; Jennifer L. Kelsey, PhD; and Michael K. Gould, MD, MS, FCCP

Η ΣΤΟΧΕΥΜΕΝΗ ΑΚΤΙΝΟΘΕΡΑΠΕΙΑ ΣΤΟΝ ΗΠX ΚΑΡΚΙΝΟ

«Τι νεώτερο στην Γυναικολογική Ογκολογία Χειρουργική αντιμετώπιση καρκίνου του τραχήλου»

Οριακά εξαιρέσιμο παγκρεατικό καρκίνωμα

Development of the Nursing Program for Rehabilitation of Woman Diagnosed with Breast Cancer

Protease-catalysed Direct Asymmetric Mannich Reaction in Organic Solvent

Studies on the Binding Mechanism of Several Antibiotics and Human Serum Albumin

2000 IU/ml χ 2 = P 0.05

Research on divergence correction method in 3D numerical modeling of 3D controlled source electromagnetic fields

Lewis Acid Catalyzed Propargylation of Arenes with O-Propargyl Trichloroacetimidate: Synthesis of 1,3-Diarylpropynes

Προενταξιακός ασθενής - Επιλογή μεθόδου κάθαρσης

Αντιθρομβωτική αγωγή στις βαλβιδοπάθειες:

(OR= %CI 1.266~1.418 P=0.000) 4.1cm NFA. [DOI] /j.issn

Δευτεροπαθής υπέρταση. Αστέριος Καραγιάννης Καθηγητής Παθολογίας ΑΠΘ Β Προπαιδευτική Παθολογική Κλινική Ιπποκράτειο Νοσοκομείο

1-4 certified reference material CRM. DSC HPLC ± 0. 4 % k = 2 P = GBW

Πρόοδοι στην Απεικόνιση με PET/CT Σε ποιές παθήσεις? Πότε?

Free Radical Initiated Coupling Reaction of Alcohols and. Alkynes: not C-O but C-C Bond Formation. Context. General information 2. Typical procedure 2

Antimicrobial Ability of Limonene, a Natural and Active Monoterpene

Effect of shengjiang powder on protection of myocardial injury in patients with sepsis

PORC (OR= %CI 1.017~1.046 P<0.001)

MUL TIL EVEL2USER2ORIENTED AGRICUL TURAL INFORMATION CLASSIFICATION

Stress Relaxation Test and Constitutive Equation of Saturated Soft Soil

Composition Analysis of Protein and Oil and Amino Acids of the Soybean Varieties in Heilongjiang Province of China

Ριζική προστατεκτομή

DCIS MR GE SIGNA HDX 1. 5T T1 T2. Magnetic Resonance Imaging MRI TR / GE Vibrant. 2. 0mL 1.

J. of Math. (PRC) 6 n (nt ) + n V = 0, (1.1) n t + div. div(n T ) = n τ (T L(x) T ), (1.2) n)xx (nt ) x + nv x = J 0, (1.4) n. 6 n

Transcript:

716 34 4 2018 4 J Clin Hepatol Vol34 No4 Apr2018 125 I 2017 R735 9 B 1001-5256 2018 04-0716 - 08 Chinese expert consensus on treatment of pancreatic cancer by radioactive 125 I particle implantation 2017 Committee of Experts on Radioactive Particle Implantation Technology Chinese Medical Doctor Association Particle Treatment Branch Committee of Minimally Invasive Therapy in Oncology Chinese Anti - cancer Association Key words pancreatic neoplasms iodine radioisotopes therapy consensus 45 8% 9 0 10 3% 4 5 > 65 23 0% 3 0 7 2000 1998 2011 2061 2007 1657 19 6 1 86% 2 1% 20 27l 7 2 70 1 8 20 90 2 5 20 10 81 6% 2004 2005 3 7 1-4 2013 45 220 38 460 4 5 8 2002 4 6 9 1 25% 5 5% 6 ~ 10 3 ~ 6 Ⅱ ~ Ⅳ 0 5 0 1990 2000 8 2 14 2340 20 9% 17 1 125 I doi 10 3969 /j issn 1001-5256 2018 04 007 2018-02 - 27 2018-02 - 27 Ljgbdgsz@ 163 com Drzfj@ 126 com

717 125 I 2017 1 2017 V1 24 10-12 NCCN NCCN 10 13 14 2 125 I 1 > 3 2 3 4 5 < 3 CT 15-16 > 6 0 cm 17 125 I 1 2 25-3 27 125 I CT CT 18 4 - - 19 - - 30 28 29 20-22 23 3 CT

718 34 4 2018 4 J Clin Hepatol Vol34 No4 Apr2018 1 30-31 1 CT MRI MPD 80 ~ 145 Gy MPD 145 Gy 39 - Perez 9 136 6 Gy NCCN 42 6 6 1 CT 3D TPS 6 2 3D 3D 33-1 2 3 K3 4 3 d 24 h 5 6 ~ 12 h 30 min 1 6 3 3D CT 3D 5 NCCN 2017 V2 37 7 5 - FU 7 1 - - + 45 ~ 54 Gy - + 2015 50 ~ 60 Gy 45 ~ 54 Gy 60 Gy /10 38

719 125 I 2017 + + Roux - en - Y - CT Y 8 CT 24 h 1 CT 72 h 44 7 2 5 ~ 7 d 45 + 9 9 1 3 > 50 ml CT 46 42 CT CT 47

720 34 4 2018 4 J Clin Hepatol Vol34 No4 Apr2018 < 50 ml 57 1 1 9 1 12 1 CNKI 1994 2016 + + 125 + + 48 9 2 γ 72 12 2 2004 1990 2000 8 2 14 2340 49 Whipple 17 1 1071 45 8% 1 9 0 2 3 242 10 3% 4 5 538 23 0% 3 0 4 TNM Ⅰ Ⅱ 18 4% 311 Ⅲ Ⅳ 81 6% 45 10 17 1 Ⅲ 1071 9 0 242 50 1000 mg /m 2 30 min 4 5 538 1 3 1 8 17 3 12 3 51 72 1099 35 11 35 1 2 4 541 TNM Ⅰ 24 Ⅱ 127 Ⅲ CT CA19-9 291 Ⅳ 99 37 558 Ⅲ 2 3 ~ 6 1 12 170 489 20 9% 1381 NCCN Ⅱ 489 Ⅰ Ⅱ 19 2 Ⅲ 12 8 31 + 29

721 125 I 2017 20 14 12 4 72 1099 676 615 91 0% 170 / 1 MA C JIANG YX LIU SZ et al Trend and prediction on the incidence of pancreatic cancer in China J Chin J Epidemiol 2013 34 2 160-163 in Chinese J 2013 34 2 160-163 2 GU K WU CX BAO PP et al Incidence of pancreatic cancer in Shanghai a current retrospective and comparative exploration J J Surg Concepts Pract 2009 14 5 510-515 in Chinese 6 MULDER I HOOGENVEEN RT van GENUGTEN ML et al Smoking cessation would substantially reduce the future incidence of pancreatic cancer in the European Union J Eur J Gastroenterol Hepatol 2002 14 12 1343-1353 7 ZHANG QH NI QX Clinical analysis of 2340 cases of pancreatic cancer J Natl Med J China 2004 84 3 214-218 in Chinese 2340 J 2004 84 3 214-218 8 JIN G SHAO Z HU XG et al Efficacy and prognosis analysis of 2061 cases of pancreatic cancer resection J Chin J Pancreatol 2013 13 1 1-4 in Chinese 2061 J 2013 13 1 1-4 9 PERETZ T NORI D HILARIS B et al Treatment of primary unresectable carcinoma of the pancreas with I - 125 implantation J Int J Radiat Oncol Biol Phys 1989 17 5 931-935 10 Notice of the General Office of the National Health and Family Planning Commission on issuing 15 administrative regulations on medical technology management practices and quality control indicators including the Management of Hematopoietic Stem Cell Transplants 2 0 1 7 Edition EB / OL http / / www moh gov cn / yzygj / s3585 / 201702 / e1b8e0c9b7c841d49c1895ecd475 d957 shtml in Chinese 2017 15 EB /OL http / /www moh gov cn/yzygj/ s3585/201702/ e1b8e0c9b7c841d49c1895ecd475d957 shtml 11 Committee of Experts on Radioactive Particle Implantation Technology Chinese Medical Doctor Association CSCO Tumor Minimally Invasive Treatment Committee Particle Therapy Branch Regulations on radioactive particle implantation treatment 2017 Edition J Natl Med J China 2017 97 19 1450-1451 in Chinese 2017 J 2017 97 19 1450-1451 12 HU XK ZHANG FJ Regulations and interpretations of radioactive particle implantation technology J Natl Med J China 2017 97 19 1441-1443 in Chinese J 2017 97 19 1441-1443 13 Committee of Experts on Radioactive Particle Implantation Technology Chinese Medical Doctor Association CSCO Tumor Minimally Invasive Treatment Committee Particle Therapy Branch Quality control index for radioactive particle implantation 2017 Edition J Natl Med J China 2017 97 19 1452-1454 in Chi- J 2009 14 5 510-515 3 CHEN Z The third national death survey report M Beijing Peking Union Medical College Publication House 2008 in Chinesenese M 2008 4 ZHANG WD MIAO SJ Analysis on epidemic characteristics of 2017 J cancer death rate in China J Chin J Health Education 2009 25 2017 97 19 1452-1454 4 246-248 in Chinese 14 CSCO Tumor Minimally Invasive Treatment Committee Particle J Therapy Branch Ward radiation protection from radioactive 125 I 2009 25 4 246-248 particle expert consensus on management standards J Natl Med 5 SIEGEL R NAISHADHAM D JEMAL A Cancer statistics 2013 J China 2017 97 19 1455-1456 in Chinese J CA Cancer J Clin 2013 63 1 11-30

722 34 4 2018 4 J Clin Hepatol Vol34 No4 Apr2018 125 I J guided fine needle aspiration in diagnosis of focal pancreatic masses 2017 97 19 1455-1456 J Endosc Ultrasound 2013 2 4 190-193 15 GAI BD DING DY SHU ZB et al Realized the operative experi- 28 GAI BD SHU ZB DING DY et al Clinical analysis of 125 I seed ence of iodine - 125 brachytherapy for pancreatic cancer J J Endocr Surg 2007 1 4 234-235 238 in Chinese al Surg 2007 14 5 582-583 in Chinese implantation for pancreatic carcinoma J Chin J Bases Clin Gener- 125 I 125 I J J 2007 1 4 234-235 238 2007 14 5 582-583 16 LYU ZW GAI BD YANG DY Interstitial implantation of 125 I seeds for stage Ⅳ pancreatic cancer J Chin J Endocr Surg 2009 2 2 95-96 in Chinese Ⅳ J 2009 2 2 95-96 17 WANG JJ ZHANG FJ Radioactive particle in tumor treatment standard M Beijing People's Medical Publishing House 2016 in Chinese M 2016 18 GAI BD XIAO ZD LIU J et al Different staging system of pancreatic carcinoma treated with 125 I seed implantation J J Endocr Surg 2008 2 4 246-248 in Chinese I J 2010 19 2 138-140 I 31 XU YJ LIU M HE XM et al 1 0T open MRI - guided 125 I seeds J 2008 2 4 246-248 percutaneous implantation for advanced pancreatic cancer J J 19 LI WW LUO KY Advances in the brachytherapy with permanent I seed implantation for pancreatic cancer J Med Recapitulate Shandong Univ Health Sciences 2017 55 2 21-25 Chinese in 2012 18 5 693-696 in Chinese 1 0T I I J J 2012 18 5 693-696 2017 55 2 21-25 20 ISHIKAWA O OHHIGASHI H SASAKI Y et al Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head J Ann Surg 1988 208 2 215-220 21 YEO CJ CAMERON JL LILLEMOE KD et al Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma part 2 randomized controlled trial evaluating survival morbidity and mortality J Ann Surg 2002 236 3 355-366 22 TOL JA GOUMA DJ BASSI C et al Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma a consensus statement by the International Study Group on Pancreatic Surgery ISGPS J Surgery 2014 156 3 591-600 23 SUN ZY LIANG HZ JIA HP et al Ultrasonographic observation on characteristics of the lymph node metastases of primary pancreatic cancer in draining regions J Chin J Med Imaging Technol 2010 26 5 904-906 in Chinese J 2010 26 5 904-906 24 National Comprehensive Cancer Network NCCN Clinical Practice Guidelines in Oncology Pancreatic Adenocarcinoma Version 1 2017 MS -11 2017-12 -31 www nccn org 25 BRUGGE WR DE WITT J KLAPMAN JB et al Techniques for cytologic sampling of pancreatic and bile duct lesions The Papanicolaou Society of Cytopathology Guidelines J Cytojournal 2014 11 Suppl 1 2 26 MICAMES C JOWELL PS WHITE R et al Lower frequency of peritoneal carcinomatosis in patients with pancreatic cancer diagnosed by EUS - guided FNA vs percutaneous FNA J Gastrointest Endosc 2003 58 5 690-695 27 OKASHA HH NAGA MI ESMAT S et al Endoscopic ultrasound - guided fine needle aspiration versus percutaneous ultrasound - 29 GAI BD LI QC YANG DY Safety analysis of ultrasound guided percutaneous 125 I radioactive seed interstitial implantation for treatment of pancreatic cancer J Chin J Endocr Surg 2016 10 3 180-181 in Chinese 125 I J 2016 10 3 180-181 30 WU YM JIN ZD Therapeutic effect of endoscopic utrasonography EUS implanted 125 I seeds for advanced stage of pancreatic carcinoma J Acta Academiae Med CPAF 2010 19 2 138-140 in Chinese 32 GUO FX JIANG YL JI Z et al 3D printed template - assisted and computed tomography image - guided 125 - iodine seed implantation for supraclavicular metastatic tumor a dosimetric study J J Peking Univ Health Sci 2017 49 3 506-511 in Chinese 3D CT 125 I J 2017 49 3 506-511 33 ZHANG HT DI XM YU HM et al Dose comparison between pre and post operation of 125 I seeds implantation guided by 3D print tamplate J Natl Med J China 2016 96 9 712-715 in Chinese 3D 125 I J 2016 96 9 712-715 34 JI Z JIANG YL GUO FX et al Dosimetry verification of radioactive seed implantation for malignant tumor assisted by 3D printing individual guide template J Chin J Radiol Med Prot 2016 36 9 662-666 in Chinese 3D J 2016 36 9 662-666 35 JIANG YL WANG H JI Z et al Computed tomography image - guided and personalized 3D printed template - assisted 125 - iodine seed implantation for recurrent pelvic tumor a dosimetric study J Chin J Radiat Oncol 2016 25 9 959-964 in Chinese CT 3D 125 I J 2016 25 9 959-964 36 GUO JH HU XK TENG GJ Radioactive particle therapy technology problems and development J Natl Med J China 2017 97 19 1444-1445 in Chinese

723 125 I 2017 J 2017 97 19 1444-1445 J 37 National Comprehensive Cancer Network NCCN Clinical Practice 2002 6 12 311-313 Guidelines in Oncology Pancreatic Adenocarcinoma Version II 2017 PANC - F 2017-12 -31 www nccn org 38 YIN WB GU XZ Radiotherapy of tumo M Beijing Peking Union Medical College Press 2008 776-782 in Chinese 47 TANG Y YU JP ZHANG DW The incidence of pancreatic fistula after 125 I seed implantation in treatment of advanced pancreatic cancer and the influencing factors J J Abdom Surg 2016 29 1 60-63 in Chinese M I 2008 776-782 J 2016 29 1 60-63 39 WANG J JING Y LI J et al Intraoperative ultrasound - guided iodine - 125 seed implantation for unresectable pancreatic carcinoma J J Exp Clin Cancer Res 2009 28 1 88-93 40 WANG CF ZHAO P LI YX et al Role of 125 I seed implantation in treatment of unresectable pancreatic cancer J Natl Med J China 2012 90 2 92-95 in Chinese 125 I biliary obstruction J J Intervent Radiol 2013 22 10 877-880 in Chinese J 2013 22 10 877-880 44 DU SY GAI BD QU J et al Comparison of effects of ultrasound - guided implantation of radioative 125 I particles in treatment of pancreatic cancer between percutaneous puncture and laparotomy J J Jilin Univ Med Edit 2017 43 2 381-385 in Chinese J 2017 43 2 381-385 45 GAI BD JIN ZT SHU ZB et al Causes analysis of postoperative complications after implantation of radioative 125 I particles in treatment of pancreatic cancer J Chin J Gen Surg 2007 22 11 873-874 in Chinese J 2007 22 11 873-874 46 GAI BD LI YC Non - operative treatment of pancreatic fistula J Chin J Modern Operative Surg 2002 6 12 311-313 in Chinese 48 HUANG HJ JIANG Y WU BQ et al Complications and prognosis of intraoperative iodine - 125 seed implantation therapy in patients with unresectable advanced pancreatic cancer J J Hepatopancreatobiliary Surg 2014 26 4 281-284 in Chinese 125 I J 2014 26 4 281-284 J 2012 90 2 92-95 49 LIU Y WANG YB DONG JH Factors for gastroparesis in treatment of post - operative pancreatic cancer patients with 125 I seed im- 41 WANG J WANG J LIAO A et al The direct biologic effects of radioactive 125 I seeds on pancreatic cancer cells PANC - 1 at continuous low - dose rates J Cancer Biother Radiopharm 2009 203 in Chinese plantation J Acad J Chin PLA Med Sch 2014 35 3 201-24 4 409-416 42 GAI BD HOU RZ LI QC Perioperative management of radioactive particles therapy for pancreatic cancer J Chin J Endocr - 203 J 2014 35 3 201 Surg 2010 4 3 196-197 in Chinese 50 BURRIS HA 3rd MOORE MJ ANDERSEN J et al Improvements in survival and clinical benefit with gemcitabine as first - line J 2010 4 3 196-197 therapy for patients with advanced pancreas cancer a randomized 43 LI MW YIN ZX HAN GH The current clinical practice of percutaneous transhepatic biliary drainage for the treatment of malignant 51 GAI BD Multidisciplinary approach for advanced pancreatic trial J J Clin Oncol 1997 15 6 2403-2413 carcinoma J Chin J Endocr Surg 2013 7 3 177-179 in Chinese J 2013 7 3 177-179 2017 11 6 444-450 125 I Committee of Experts on Radioactive Particle Implantation Technology Chinese Medical Doctor Association Particle Treatment Branch Committee of Minimally Invasive Therapy in Oncology Chinese Anti - cancer Association Chinese expert consensus on treatment of pancreatic cancer by radioactive 125 I particle implantation 2017 J J Clin Hepatol 2018 34 4 716-723 125 I in Chinese 125 I 2017 J 2018 34 4 716-723