Μαργαρίτα Τζαφλίδου. Ελληνική. Έγγαµος, µητέρα δύο παιδιών

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1 BIOΓPAΦIKO ΣHMEIΩMA Όνοµα Μαργαρίτα Τζαφλίδου ιεύθυνση Εργασίας Εργαστήριο Ιατρικής Φυσικής, Σχολή Επιστηµών Υγείας, Πανεπιστήµιο Ιωαννίνων Ιωάννινα Τηλέφωνο: Fax: Εθνικότητα Οικογενειακή Κατάσταση Ελληνική Έγγαµος, µητέρα δύο παιδιών Σπουδές Πανεπιστήµιο Ιωαννίνων, Τµήµα Φυσικό, Φυσικοµαθηµατική Σχολή, Πτυχίο: Φυσικής University of Manchester, U.K., Department of Medical Biophysics, Medical School, Πτυχίο: Ph.D. Παρούσα Θέση Καθηγήτρια Ιατρικής Φυσικής, Ιατρικού Τµήµατος, Πανεπιστηµίου Ιωαννίνων ιευθυντής Εργαστηρίου Ιατρικής Φυσικής Κοσµήτωρ Σχολής Επιστηµών Υγείας, Πανεπιστηµίου Ιωαννίνων Προηγούµενες ιοικητικές Θέσεις ιευθυντής Μορφολογικού-Κλινικοεργαστηριακού Τοµέα,Ιατρικής Σχολής Πανεπιστηµίου Ιωαννίνων ( ) Αναπληρωτής Πρόεδρος Ιατρικής Σχολής, Πανεπιστηµίου Ιωαννίνων ( ) Πρόεδρος Ιατρικής Σχολής, Πανεπιστηµίου Ιωαννίνων ( ) Υποτροφίες : υποτροφία του Ιδρύµατος Αλέξανδρος Ωνάσης µε σκοπό την απόκτηση PhD στο Department of Medical Biophysics, Medical School, Manchester University, UK 1981, 1983, 1984: υποτροφία του British Council για µεταδιδακτορική έρευνα στο ανωτέρω Τµήµα 2001: υποτροφία ΝΑΤΟ (senior fellowship) ενός µηνός για έρευνα στο Medical Radiological Research Centre Obninsk, Ρωσία Άλλες Υπευθυνότητες ιευθυντής Σύνταξης του ιεθνούς Επιστηµονικού Περιοδικού TheScientificWorldJOURNAL (Microscopy Domain, Biometrics Domain) έως το Καλοκαίρι 2011 Μέλος της Επιτροπής Σύνταξης του ιεθνούς Επιστηµονικού Περιοδικού «MICRON» έως το 2010

2 Μέλος της Επιτροπής Σύνταξης των ιεθνών Επιστηµονικών Περιοδικών Journal of Biological Engineering και TheScientificWorldJOURNAL (Biophysics Domain) Representative της UNESCO στις Επιστήµες Ζωής στην Ελλάδα στο πεδίο της Βιοφυσικής Κριτής σε ιεθνή Επιστηµονικά Περιοδικά: 1) Micron 2) Scanning Microscopy 3) TheScientificWorldJOURNAL 4) Biochimica et Biophysica Acta 5) Physics in Medicine and Biology 6) IEEE Journal Transactions on Nuclear Science 7) Skin Pharmacology and Physiology 8) Applied Radiation and Isotopes 9) Journal of Materials Research 10) Journal of Physics D: Applied Physics 11) Materials Science and Engineering B Acta Biomaterialia 12) Acta Biomaterialia 13) Materials 14) International Journal of Biological Engineering 15) Microscopy and Microanalysis 16) Computers in Biology & Medicine 17) Measurement Science and Technology 18) Biomedical Materials 19) Physical Review & Research International 20) International Journal of Medical Sciences Evaluator: στην Ευρωπαϊκή Ένωση, στο ERC, στο INTAS, στη Γενική Γραµµατεία Έρευνας και Τεχνολογίας Ελλάδας, στο Υπουργείο Παιδείας Ελλάδας, στο Υπουργείο Παιδείας και Έρευνας Ιταλίας (MIUR), στα Υπουργεία σχετικά µε έρευνα και υποδοµές της Σλοβακίας και Τσεχίας. Επισκέπτης Καθηγητής του Πανεπιστηµίου Βελιγραδίου, Σερβία Τρέχουσες ιδακτικές Υποχρεώσεις Οργάνωση και διδασκαλία του µαθήµατος Ιατρικής Φυσικής στους φοιτητές Ιατρικού Τµήµατος, Πανεπιστηµίου Ιωαννίνων Επιβλέπουσα σε 7 διδακτορικές διατριβές Φοιτητικά Συγγράµµατα Medical Physics: Bioelectricity Optics Heat Cold, ISBN , Published by Gutenberg, Athens, 2010 Βιοηλεκτρισµός (µε ΙΑΤΡΙΚΟ προσανατολισµό), Εκδόσεις Πανεπιστηµίου Ιωαννίνων, Ιωάννινα 2008 Οπτική (µε Εφαρµογές στις Ιατρικές Επιστήµες), Εκδόσεις Πανεπιστηµίου Ιωαννίνων, Ιωάννινα 1998 Βιοφυσική, Εκδόσεις Πανεπιστηµίου Ιωαννίνων, Ιωάννινα 1993 Ηλεκτρονικό Μικροσκόπιο, Εκδόσεις Πανεπιστηµίου Ιωαννίνων, Ιωάννινα 1994

3 Άλλες ραστηριότητες 1) Η καθ. κ. Μ. Τζαφλίδου οργάνωσε εξ ολοκλήρου στο Εργαστήριο Ιατρικής Φυσικής, τη Μονάδα Βιοφυσικής η οποία έχει παράγει αυτοτελώς πάνω από 100 ερευνητικές εργασίες και έχει πάνω από 100 συµµετοχές σε Επιστηµονικά Συνέδρια. Επιπλέον έχουν περατωθεί διδακτορικές διατριβές και διπλωµατικές εργασίες. Η ανωτέρω Μονάδα συνεργάζεται µε άλλες ερευνητικές οµάδες τόσο του εσωτερικού όσο και του εξωτερικού. Οι ερευνητικές δραστηριότητες καλύπτουν ένα ευρύ φάσµα αντικειµένων στο χώρο των 1) Eπιστηµών Υγείας: συνδετικοί ιστοί, δράση φαρµάκων, ηλεκτρονική µικροσκοπία (ΤΕΜ, SEM), ανάλυση εικόνας, µοντελισµός πρωτεϊνών, µελέτη σύστασης του ανθρωπίνου σώµατος, ιχνοστοιχεία, µικροδοµή οστών µε τις ακόλουθες τεχνικές: image analysis, neutron activation analysis, X-ray absorptiometry, microct tomography, X-ray microfluorescence, Auger spectroscopy, FTIR, 2) Ηλεκτροµαγνητισµού: βιολογικές επιπτώσεις, δοσιµετρία, ηλεκτρονικά, 3) Ιατρικής Βιοτεχνολογίας: ηλεκτρονικά στην Ιατρική, 4) Ιατρικής Πληροφορικής: ανάλυση εικόνας, ανθρώπινα δίκτυα 5) Βιοµετρικής και 6) ιεθνούς Εκπαίδευσης. 2) Συντάκτης (Guest Editor) για έξι ειδικούς τόµους: Tεσσάρων ειδικών τόµων του ιεθνούς Επιστηµονικού Περιοδικού «Micron» µε τους ακόλουθους τίτλους: α) Collagen: Image Processing and Quantitative Ultrastructural Studies,vol. 32 (3), , β) Biological Effects of Radiation: Role of Electron Microscopy, vol.33 (2), , γ) Morphological and Functional Changes in Aging Skin, vol. 35 (3), , δ) Bone Structure in Health and Disease, vol. 36, (7-8), , ύο ειδικών τόµων του ιεθνούς Επιστηµονικού Περιοδικού TheScientificWorldJOURNAL µε τίτλους: a) Biological Effects of Electromagnetic Radiation, vol. 4, Issue S2, 1-104, b) Biometrics Applications: Technology, Ethics, and Health Hazards, vol. 11, , ) Η καθ. κ. Μ. Τζαφλίδου είναι Representative της UNESCO στην Ελλάδα σε θέµατα Βιοφυσικής (από το 1998) όσον αφορά το Life Sciences International Higher Educational School (LSIHES) υπό την αιγίδα της UNESCO. Στο πλαίσιο των δραστηριοτήτων αυτών έχει πάρει µέρος σε δύο σεµινάρια, οργανωµένα από την UNESCO, µε θέµατα «Μodern Cellular and Molecular Biophysics» (1998) και «Cellular Mechanism on Beneficial and Harmful Effects of Electromagnetic Fields» (2000) Έχει επίσης ενεργό συµµετοχή στην οργάνωση για λογαριασµό της UNESCO, του Εκπαιδευτικού Συστήµατος εξ αποστάσεως (Distance Educational System) που κυρίως θα περιλαµβάνει χώρες της Ασίας και Μαύρης Θάλασσας.

4 4) Είναι µέλος 11 Επιστηµονικών Εταιρειών Προσκεκληµένος Οµιλητής σε Πανεπιστήµια του Εξωτερικού Έδωσε 37 διαλέξεις ως προσκεκληµένη σε 26 Πανεπιστήµια και Ερευνητικά Ινστιτούτα του εξωτερικού Συµµετοχή σε ιεθνή Συνέδρια Συµµετείχε σε πάνω από 100 ιεθνή Συνέδρια είτε µε ανακοινώσεις είτε µε άρθρα. ηµοσιεύσεις 1) M. Tzaphlidou, J.A. Chapman and K.M. Meek. A study of positive staining for electron microscopy using collagen as a model system. I. Staining by phosphotungstate and tungstate ions. Micron, 13, , ) M. Tzaphlidou, J.A. Chapman and M.H. Al-Samman. A study of positive staining for electron microscopy using collagen as a model system. II. Staining by uranyl ions. Micron, 13, , ) M. Tzaphlidou. The effects of fixation by combination of glutaraldehyde/dimethyl suberimidate. Use of collagen as a model system. J. Histoch. Cytoch. 31, , ) M. Tzaphlidou and R.A. Hardcastle. A computer method for the comparison or the quantitative similarity between normal and abnormal collagen or between sequence data and experimental data. Int. J. Bio-Medical Computing, 15, , ) M. Tzaphlidou and J.A. Chapman. A study of positive staining for electron microscopy using collagen as a model system. III. The effects of suberimidate fixation. Micron Microscopica Acta, 15, 69-76, ) M. Tzaphlidou. Negative staining electron microscopy of collagen fibrils. "Invited Article" Micron Microscopica Acta, 7, , ) M. Tzaphlidou and J.A. Chapman. A study of staining for electron microscopy using collagen as a model system. IV. Phosphotungstate/tungstate negative staining patterns and their correlation with sequence data. Micron Microscopica Acta, 17, , ) M. Tzaphlidou. A study of staining for electron microscopy using collagen as a model system. V. The effect of suberimidate fixation on negative staining patterns. Micron Microscopica Acta, 17, , ) M. Tzaphlidou. Collagen cross-linking produced by dimethyladipimidate. Its comparison with dimethylsuberimidate. Micron Microscopica Acta, 18, 55-58, ) M. Tzaphlidou and J.A. Chapman. A study of staining for electron microscopy using collagen as a model system. VI. Uranyl nitrate negative staining patterns and their correlation with sequence data. Micron Microscopica Acta, 18, , ) D.P. Matthopoulos and M. Tzaphlidou. Tissue culture fixation with diimidoesters. I. Comparison of structure obtained with diimidoesters and formaldehyde. Micron Microscopica Acta, 18, , ) M. Tzaphlidou and D.P. Matthopoulos. Diimidoesters: Role in electron and light microscopy. "Invited Article" Micron Microscopica Acta, 19, 1-12, 1988

5 13) M. Tzaphlidou. Staining for electron microscopy by vanadyl sulfate. Use of collagen as a model system. Micron Micoscopica Acta, 19, , ) M. Tzaphlidou and D.P. Matthopoulos. Penetration rate of dimethyladipimidate. Use of gelatin gels as model system. Micron Microscopica Acta, 19, , ) D.P. Matthopoulos and M. Tzaphlidou. Tissue culture fixation with diimidoesters. II. The development of the vimentin type filament network of monkey kidney CV1 cells. Micron Microscopica Acta, 19, 13-17, ) D.P. Matthopoulos and M. Tzaphlidou. The effect of elevated temperature on the aggregation of African green monkey kidney cells. Cell Biol. Int. Rep., 12, , ) J.A. Chapman and M. Tzaphlidou. A study of staining for electron microscopy using collagen as a model system. VIII. Simulation of the negative staining patterns. Micron Microscopica Acta, 20, 75-87, ) D.P. Matthopoulos and M. Tzaphlidou. Tissue culture fixation with diimidoesters. III. Influence of adipimidate on cell size, thermal and mechanical stability. Micron Microscopica Acta, 20, , ) J.A. Chapman, M. Tzaphlidou, K.M. Meek and K.E. Kadler. The collagen fibril - A model system for studying the staining and fixation of a protein. Electron Microscopy Reviews, 3, , ) D.P. Matthopoulos and M. Tzaphlidou. Tissue culture fixation with diimidoesters. IV. A comparison between adipimidate and aldehydes of their effects on cell size and morphology. Micron Microscopica Acta, 21, 69-76, ) M. Tzaphlidou. The negative staining pattern of collagen fibrils as studied by electron microscopy. The effect of fixation. Micron Microscopica Acta, 22, , ) M. Tzaphlidou, K.C. Siamopoulos and D. Glaros. Abnormal collagen fibril structure of skin in chronic haemodialysis patients: An electron microscopic study. Micron Microscopica Acta, 22, 1-8, ) M. Tzaphlidou. The positive staining pattern of skin collagen in chronic haemodialysis patients. Micron Microscopica Acta, 22, 17-19, ) M. Tzaphlidou, I. Leontiou and D. Glaros. The effect of gamma irradiation on the organization of mouse skin collagen fibrils. The positive staining pattern. Micron MIcroscopica Acta, 22, , ) M. Tzaphlidou, C. Cummings and J.A. Chapman. A study of staining for electron microscopy using collagen as a model system. IX. The effect of tannic acid fixation. Micron Microscopica Acta, 23, 25-35, ) M. Tzaphlidou. Abnormal collagen fibril structure as studied by electron microscopy. Electron Microsc. Rev., 5, 25-35, ) I. Leontiou, D.P. Matthopoulos, M. Tzaphlidou and D. Glaros. The effect of gamma irradiation in collagen fibril structure. Micron, 24, 13-16, ) E. Kounadi, M. Tzaphlidou and D. Glaros. An electron microscopic study of collagen fibril structure after lithium treatment - I. The effect of different lithium doses on mouse skin collagen. Micron, 25, , 1994.

6 29) E. Kounadi, M. Tzaphlidou, G. Fountos and D. Glaros. An electron microscopic study of collagen fibril structure after lithium treatment - II. The effects of low lithium dose and short treatment on mouse skin collagen. Micron, 26, , ) D.P. Matthopoulos, M. Tzaphlidou and I. Leontiou. Morphological alterations caused by lithium in various cell lines. Cell Biol. Int., 19, , ) M. Tzaphlidou, E. Kounadi, I. Leontiou, D.P. Matthopoulos and D. Glaros. The influence of low doses gamma irradiation on mouse skin collagen fibrils. International Journal of Radiation Biology, 71, , ) G. Fountos, E. Kounadi, M. Tzaphlidou, D. Glaros and S. Yasumura. Changes in the skeletal Ca/P ratio and collagen morphology in rabbits fed a diet low in Ca, P, and vitamin D, or made osteopenic by inflammation The FASEB Journal, 11, 2240, ) E. Kounadi, G. Fountos and M. Tzaphlidou. The influence of inflammation-mediated osteopenia (IMO) on the structure of rabbit bone and skin collagen fibrils. Connective Tissue Research, 37, 69-76, ) M. Tzaphlidou and E. Kounadi. The effect of lithium treatment on collagenous tissues: an electron microscope study. Micron, 29, , ) G. Fountos, E. Kounadi, M. Tzaphlidou, S. Yasumura and D. Glaros. The effects of inflammation-mediated osteoporosis (IMO) on the skeletal Ca/P ratio and on the structure of rabbit bone and skin collagen. Appl. Radiat. Isot., 49, , ) G. Fountos, M. Tzaphlidou, E. Kounadi and D. Glaros. In vivo measurement of radius calcium/phosphorus ratio by X-ray absorptiometry. Appl. Radiat. Isot., 51, , ) M. Tzaphlidou. Image processing of collagen: role in medicine. Folia medica 41, 11-14, ) M. Tzaphlidou. Side effects of lithium treatment on collagenous tissues. Folia medica 41, 15-19, ) H. Kafantari, E. Kounadi, M. Fatouros, M. Milonakis and M. Tzaphlidou. Structural alterations in rat skin and bone collagen fibrils induced by ovariectomy. Bone, 26, , ) M. Tzaphlidou and H. Kafantari. Influence of nutritional factors on bone collagen fibrils in ovariectomized rats. Bone, 27, , ) M. Tzaphlidou, G. Fountos and D. Glaros. Bone Hydroxyapatite/Collagen Ratio: In Vivo Measurements by X-ray Absorptiometry. Annals of The New York Academy of Sciences, 904, , ) M. Tzaphlidou, E. Kounadi and H. Kafantari. Influence of lithium on mouse bone collagen fibrils. J. Trace and Microprobe Techniques, 18, , ) M. Tzaphlidou. Diameter distributions of collagenous tissues in relation to sex. A quantitative ultrastructural study. Micron, 32, , ) M. Tzaphlidou. Measurement of the axial periodicity of collagen fibrils using an image processing method. Micron, 32, , ) B. Eyden and M. Tzaphlidou. Structural variations of collagen in normal and pathological tissues: role of electron microscopy. Micron, 32, , 2001.

7 46) M. Tzaphlidou. Collagen as a model for the study of radiation induced side effects. Use of image processing. Micron, 33, , ) M. Tzaphlidou and P. Berillis. Structural alterations caused by lithium in skin and liver collagen using an image processing method. J. Trace Microprobe Tech., 20, , ) V. Zaichick and M. Tzaphlidou. Determination of calcium, phosphorus, and the calcium/phosphorus ratio in cortical bone from the human femoral neck by neutron activation analysis. Applied Rad Isot., 56, , ) M. Tzaphlidou and V. Zaichick. Neutron activation analysis of calcium/phosphorus ratio in rib bone of healthy humans. Applied Rad Isot., 57, , ) M. Tzaphlidou. Side effects of lithium on rat cranial arachnoid and dura mater collagen. A quantitative ultrastructural study. J Trace Elem. Exp. Med., 16, 17-26, ) V. Zaichick and M. Tzaphlidou. Calcium, phosphorus concentrations and the calcium/phosphorus ratio in trabecular bone from the femoral neck of healthy humans as determined by neutron activation analysis. Appl. Rad. Isotop., 58, , ) M. Tzaphlidou and V. Zaichick. Calcium, Phosphorus, Calcium-Phosphorus ratio in rib bone of healthy humans. Biol. Trace Elem. Res., 93, 63-74, ) M. Tzaphlidou and V. Zaichick. Sex and age related Ca/P ratio in cortical bone of iliac crest of healthy humans. J. Radioanal. Nucl. Chem., 259, , ) M. Tzaphlidou. The role of collagen and elastin in aged skin: an image processing approach. Micron, 35, , ) M. Tzaphlidou and M. Zervakis. Aged skin: detection of alterations of major collagen types ratio by image processing of electron-optical data. Micron, 35, , ) M. Tzaphlidou and P. Berillis. Effect of lithium administration on collagen and breaking pressure of the rat thoracic descending aorta. J. Trace Elem. Exp. Med., 17, , ) M. Tzaphlidou. Collagenous tissues upon lithium treatment: A quantitative ultrastructural study. TheScientificWorldJOURNAL 4, , ) M. Tzaphlidou and E. Fotiou. The effects of 910-MHz electromagnetic field on rat cranial arachnoid and dura mater collagen. The axial periodicity of collagen fibrils. TheScientificWorldJOURNAL 4 (S2),70-74, ) M. Tzaphlidou, E. Fotiou, Ch. Gousias and D.P. Matthopoulos. Development of a reliable and low cost system for the study of EMF biological effects. TheScientificWorldJOURNAL 4 (S2), , ) V. Kyriazis and M. Tzaphlidou. Skeletal calcium/phosphorus ratio measuring techniques and results, part I: microscopy and microtomography. TheScientificWorldJOURNAL 4, , ) M. Tzaphlidou, R. Speller, G. Royle, J. Griffiths, A. Olivo, S. Pani and R. Longo. High resolution Ca/P maps of bone architecture in 3-D synchrotron radiation microtomographic images. Appl. Rad. Isotop., 62, , 2005.

8 62) R. Speller, S. Pani, M. Tzaphlidou and J. Horrocks. MicroCT analysis of calcium/phosphorus ratio maps at different bone sites. Nuclear Instruments and Methods in Physics Research A, 548, , ) A. Iglic, M. Tzaphlidou, M. Remskar, B. Babnik, M. Daniel and V. Kralj-Iglic. Stable shapes of thin anisotropic nano-strips. Fullerenes, Nanotubes and Carbon Nanostructures, 13, , ) V. Kyriazis and M.Tzaphlidou. Skeletal calcium/phosphorus ratio measuring techniques and results: neutron activation analysis and x-ray absorptiometry. J. Radioanal. Nucl. Chem., 265, , ) M. Zervakis, V. Gkoumplias and M. Tzaphlidou. Analysis of fibrous proteins from electron microscopy images. Medical Engineering and Physics, 27, , ) V. Gkoumplias, M. Zervakis and M. Tzaphlidou. An automated approach for analyzing D-periods in collagen fibril images. IEEE Transactions on Biomedical Engineering, 52, , ) M. Tzaphlidou. The role of collagen in bone structure: an image processing approach. Micron, 36, , ) M. Tzaphlidou and P. Berillis. Collagen fibril diameter in relation to bone site. A quantitative ultrastructural study. Micron, 36, , ) M. Tzaphlidou, P. Berillis and D. Matthopoulos. Bone calcium, phosphorus detection by Auger electron spectroscopy. Micron, 36, , ) M. Tzaphlidou, R. Speller, G. Royle and J. Griffiths. Preliminary estimates of the calcium/phosphorus ratio at different cortical bone sites using synchrotron microct. Physics in Medicine and Biology, 51, , ) P. Berillis, D. Emfietzoglou and M. Tzaphlidou. Collagen fibril diameter in relation to bone site and to calcium/phosphorus ratio. TheScientificWorldJOURNAL, 6, , ) M. Tzaphlidou. Bone architecture: Collagen structure and calcium/phosphorus maps. Journal of Biological Physics, 34, 39-49, ) W. Kaabar, O. Gundogdu, M. Tzaphlidou, M. Janousch, D. Attenburrow, and D.A. Bradley. Investigation of essential element distribution in the equine metacarpophalangeal joint using a synchrotron radiation micro x-ray fluorescence technique. AIP Conference Proceedings, 1017, 18-24, ) N. Kourkoumelis, and M. Tzaphlidou. Spectroscopic assessment of normal cortical bone: differences in relation to bone site and sex. TheScientificWorldJOURNAL,10, , ) N. Kourkoumelis, and M. Tzaphlidou. Medical safety issues concerning the use of incoherent infrared light in biometrics. Lecture Notes in Computer Science (Ethics and Policy of Biometrics) Ajay Kumar, David Zhang (Eds.), Springer-Verlag Berlin Heidelberg, , ) N. Kourkoumelis, and M. Tzaphlidou. Multivariate statistical evaluation of bone site and sex as parameters for the Fourier transform infrared spectroscopic study of normal bone. Spectroscopy, 24, , 2010.

9 77) I. Balatsoukas, N. Kourkoumelis and M. Tzaphlidou. Auger electron spectroscopy for the determination of sex and age related Ca/P ratio at different bone sites. Journal of Applied Physics, 108, , ) N. Kourkoumelis and M. Tzaphlidou. Eye safety related to near infrared radiation exposure to biometric devices. TheScientificWorldJOURNAL,11, , ) L. Astrakas, C. Gousias and M. Tzaphlidou. Electric field effects on chignolin conformation. Journal of Applied Physics, 109, , ) N. Kourkoumelis, I. Balatsoukas, and M. Tzaphlidou. Ca/P concentration ratio at different sites of normal and osteoporotic rabbit bones evaluated by Auger and energy dispersive x-ray spectroscopy. Journal of Biological Physics, 38, , ) L. Astrakas, C. Gousias and M. Tzaphlidou. Structural destabilization of chignolin under the influence of oscillatingelectric fields. Journal of Applied Physics, 111, , ) G. Gaitanis, P. Spyridonos, K. Patmanidis, V. Koulouras, G. Nakos, M. Tzaphlidou and I. D. Bassukas. Treatment of toxic epidermal necrolysis with the combination of infliximab and high-dose intravenous immunoglobulin. Dermatology, 224, , ) N. Kourkoumelis, A. Lani and M. Tzaphlidou. Infrared spectroscopic assessment of the Inflammation Mediated Osteoporosis (IMO) model applied on rabbit bone. Journal of Biological Physics, 38, , ) A. Hadjipanteli, J. Huang, P. Fromme, N. Kourkoumelis, A. Olivo, M. Tzaphlidou and R. Speller. Development of a new technique for the investigation of the 3d spatial distribution of the calcium/phosphorus ratio effect in osteoporosis Osteoporosis International, 23, S605, ) N. Kourkoumelis, A. Polymeros and M. Tzaphlidou. Background estimation of biomedical Raman spectra using a geometric approach. Spectroscopy, 27, , ) D.E. Ziogas, C.S. Katsios, M. Tzaphlidou and D.H. Roukos. Targeted therapy: overcoming drug resistance with clinical cancer genome. Expert Rev Anticancer Therapy, 12, , ) D.E. Ziogas, G. Baltogiannis, J. Spiliotis, M. Tzaphlidou and D.H. Roukos. Genomebased diagnostics and predictive tools: a new epoch for breast cancer management. Future Oncol., 8, , ) C.S. Katsios, C. Papaloukas, M. Tzaphlidou and D.H. Roukos. Next-generation sequencing-based testing for cancer mutational landscape diversity: clinical implications? Expert Rev. Mol. Diagn., 12(7), , ) C.S. Ku, D.N. Cooper, D.E. Ziogas, E. Halkia, M. Tzaphlidou and D.H. Roukos. Research and clinical applications of cancer genome sequencing. Curr Opin Obstet Gynecol, 25, 3-10, ) D.H. Roukos, C. Papaloukas and M. Tzaphlidou. From targeted monotherapy to combined BRAF-MEK inhibitors and integrated genome analysis for melanoma treatment. Future Oncol., 9 (1), 5-8, ) P. Spyridonos, G. Gaitanis, I.D. Bassukas and M. Tzaphlidou. Gray Hausdorff distance measure for medical image comparison in dermatology: Evaluation of treatment effectiveness by image similarity. Skin Research and Technology, 19, e , 2013.

10 Editorial Άρθρα 1. M. Tzaphlidou. Collagen: Image Processing and Quantitative Ultrastructural Studies. Micron, 32 (3), 221, M. Tzaphlidou. Biological Effects of Radiation: Role of Electron Microscopy. Micron, 33 (2), 115, M. Tzaphlidou and J. Hatzis. Morphological and Functional Changes in Aging Skin. Micron, 35 (3), 153, M. Tzaphlidou and Z. Somosy. Biological effects of electromagnetic radiation. TheScientificWorldJOURNAL, 4(S2), 1-3, M. Tzaphlidou. Bone Structure in Health and Disease. Micron, 36 (7-8), 565, M. Tzaphlidou and F.N. Pavlidou. Biometrics applications: technology, ethics, and health hazards. TheScientificWorldJOURNAL, 11, , 2011 Ανασκόπηση Βιβλίου 1. M. Tzaphlidou and D. Matthopoulos. Hair science and technology. Micron, 35 (3), 227, 2004 Άρθρα σε ιεθνή Βιβλία 1) M. Tzaphlidou. Role of the collagen fibril positive staining pattern in determining lithium side effects on collagen. In: Lithium - 50 years: Recent advances in biology and medicine, Lucas, K.C., Becker, R.W., Gallicchio, V.S. eds. Weidner Publishing Group, Chesire, Connecticut, pp , ) M. Tzaphlidou. Role of cross-linking in collagen structural alterations brought about by lithium. In: Lithium - 50 years: Recent advances in biology and medicine, Lucas, K.C., Becker, R.W., Gallicchio V.S. eds. Weidner Publishing Group, Chesire, Connecticut, pp , ) M. Tzaphlidou. Computer-aided Techniques for the Ultrastructural Study of a Protein. In: Modern Problems of Cellular and Molecular Biophysics, Ayrapetyan, S.N., North, A.C.T. eds. Noyan Tapan-Armenia by UNESCO Chair-Life Sciences International Educational Center, pp , ) M. Tzaphlidou. The Collagen Fibril A Model System for Studying Structural Properties, as well as Staining and Fixation of a Protein. In: Modern Problems of Cellular and Molecular Biophysics, Ayrapetyan, S.N., North, A.C.T. eds. Noyan Tapan-Armenia by UNESCO Chair-Life Sciences International Educational Center, pp , ) M. Tzaphlidou. Side effects of lithium on various tissues: Use of collagen as a model system. In: Trends in Physiological Sciences. Cells to Systems, Mohammad Fahim ed., Serials Publications, Delhi-India, pp. 1-16, ) M. Tzaphlidou and E. Fotiou. Collagen as a target for electromagnetic fields. Effects of 910-MHz on rat brain. In: BIOELECTROMAGNETICS Current Concepts NATO Series B:

11 Physics and Biophysics, S.N. Ayrapetyan and M.S. Markov (eds.), Springer, The Netherlands, pp , ) M. Tsipouras, D. Tsalikakis, L. Astrakas, S. Konitsiotis, M. Tzaphlidou and A. Tzallas. Automated Epileptic Seizure Detection Methods: A Review Study. In: Epileptic Seizures Book ISBN Book edited by: Dr. Dejan Stevanovic, INTECH Open Access Publisher, Croatia, ) M. Tzaphlidou, C. Papaloukas and D.H. Roukos. Integrating NGS and third-generation sequencing technologies into clinical genomic medicine. Chapter 1, Future Medicine 2012,