Bone mineral density of cancellous bone in edentulous areas: quantitative CT measurement

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1 Chinese Journal of Tissue Engineering Research December 28, 2017 Vol.21, No.36 CT ( ). CT [J] (36): DOI: /j.issn ORCID: X() CT CT CT 1990 CT CBCT CT X CT CT CT CT CT mg/cm CT :R318 :A : (2017) CT CT CT CT 90 CT ()(mg/cm ) (P < 0.001) (P < 0.05)> >>(P < 0.05) CT CT CT (2017JY0111)(16PJ174) Bone mineral density of cancellous bone in edentulous areas: quantitative CT measurement Huang Ying, Zhang Hui, Cai Yue, Zeng Fan-gang, Guo Ling ( Department of Prosthodontics, Department of Radiology, Hospital of Stomatology Affiliated to Southwest Medical University, Luzhou , Sichuan Province, China) Abstract BACKGROUND: The bone mineral density (BMD) in unit volume can be accurately measured with the theory of quantitative CT. After tooth loss, bone resorption certainly exists in the alveolar bone healing. Therefore, it is important to accurately evaluate the BMD of cancellous bone in the plantation area before implantation. OBJECTIVE: To evaluate the changes in BMD of alveolar cancellous bone after the loss of tooth, and explore whether the BMD shows the differences in different genders, ages and dental sites. Huang Ying, Studying for master s degree, Physician, Department of Prosthodontics, Hospital of Stomatology Affiliated to Southwest Medical University, Luzhou , Sichuan Province, China Corresponding author: Guo Ling, M.D., Associate professor, Department of Prosthodontics, Hospital of Stomatology Affiliated to Southwest Medical University, Luzhou , Sichuan Province, China ISSN CN /R CODEN: ZLKHAH 5775

2 . CT METHODS: Corrected voxel values were obtained from the cone-beam CT with the theory of quantitative CT. Ninety patients underwent cone-beam CT, and their BMD (mg/cm ) in dentulous areas and control areas (homonymous region of the same jaw) was obtained. RESULTS AND CONCLUSION: The BMD of alveolar cancellous bone reduced after the loss of tooth (P < 0.001). The BMD reduction of the edentulous cancellous bone, normal cancellous bone and the cancellous bone after tooth loss had no correlation with gender. The BMD reduction of the edentulous cancellous bone and the cance llous bone after tooth loss was not associated with age (P > 0.05), while the BMD of the control area decreased with increasing age (P < 0.05). The order of the BMD of cancellous bone was as follows: mandibular posterior region > mandibular anterior region > maxillary anterior region > maxillary posterior region. To conclude, quantitative CT is a available method for detecting the changes in the BMD of alveolar cancellous bone after tooth loss. Subject headings: Tissue Engineering; Bone Density; Mandible; Maxilla Funding: a grant from the Science and Technology Department of Sichuan Province, No. 2017JY0111; the Project of Sichuan Provincial Health and Family Planning Commission, No. 16PJ174 Cite this article: Huang Y, Zhang H, Cai Y, Zeng FG, Guo L. Bone mineral density of cancellous bone in edentulous areas: quantitative CT measurement. Zhongguo Zuzhi Gongcheng Yanjiu. 2017;21(36): Introduction CT(cone-beam computed tomography CBCT) CT [1] CT CT [2-3] CT [3] CT(quantitative computed tomographyqct) XCT CT (region of interestroi) CT [4] CT(bone mineral densitybmd) X(dual-energy X-ray absorptiometry DXA) [5] CTCT 1Subjects and methods CT (45±13) 18/ 3 6 () 1.4 (K 2 HP 4 ) ()Naitoh [5] mg/cm 3 K 2 HP 4 15 ml CT K 2 HP 4 CT(pax-uni3D CT89 kvp 8.0 ma cm 8.0 cm) DicomEz3D plus 1 mm2 mm 10 CT(1)10CT CT CT DicomEz3D plus 4 1 CT(2) P.O. Box 10002, Shenyang

3 . CT CT (3) CT CTCT1 2 CT 1.6 CT CT 1.7 SPSS 17.0 K 2 HP 4 CT CT (mg/cm 3 )x±s t () t () t () α=0.05 2Results CTr =0.947 P < 0.05CT R =0.897 F =69.708P < 0.05 CTt t=1.953p < 0.05CT y= x(4) CT(HU) (mg/cm 3 ) t r =0.889 P < t P < t ()(P > 0.05) ()(2) 2.5 () 3 () () (P > 0.05)3 () (P < 0.053) t (P < 0.05) > () 4 ()(P > 0.05) (P < ) t (P < 0.05) >>> 3Discussion [7] CT CT CT [8] CTX [9-10] CT [11-12] CT CT CT [13-14] CT X CTCTX [314] ISSN CN /R CODEN: ZLKHAH 5777

4 . CT A B 1 K HP CT Figure 1 The cone-beam CT values of the K HP body models CT 2 CT Figure 2 Cone-beam CT values of the proximal cancellous bone in the edentulous area A B CT A B CBCT (HU) CT Figure 3 Cone-beam CT values of the proximal cancellous bone in the control area A B CT (mg/cm³) 4 CT(CBCT) Figure 4 Linear regression fitting of the liquid concentration and cone-beam CT values 1 Table 1 Basic information of the participants n (x±s) 42±14 49±12 45±13 (x±smg/cm ) (x±smg/cm ) ± ± ± ± ± ± ( ) (x ±smg/cm ) Table 2 Comparison of cancellous bone mineral density between the edentulous area and control area and their difference value of different sexes n () ± ± ± ± ± ±16.75 (P > 0.05) 3 ( ) (x±smg/cm ) Table 3 Comparison of cancellous bone mineral density between the edentulous area and control area and their difference value at different ages () n () ± ± ± ± ± ±24.98 > ± ± ±28.52 (P < 0.05) 4 ( ) (x±smg/cm ) Table 4 Comparison of cancellus bone mineral density between the edentulous area and control area and their difference value at different dental sites n () ± ± ± ± ± ± ± ± ± ± ± ±52.68 (P < 0.05) 5778 P.O. Box 10002, Shenyang

5 . CT X X [15-16] CT CTX CTCTCT(HU) (mg/cm 3 )CT CT [17-18] CT (Ca 5 OH(PO 4 )) (K 2 HP 4 ) [19] CT CT 3 70%80% [20-21] 1.2 mm4.4 mm [22] [23] [24-25] [26] > [27-28] 30%50% 2%3%30% % () 60 CT >>> [29-30] Norton [31] Fanuscu [32] CT51529 HU HU CTCT Turkyilmaz [33] ( ) CT CNKI 3 ISSN CN /R CODEN: ZLKHAH 5779

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