ΕΠΑΜΕΙΝΩΝΔΑΣ Β. ΤΣΙΑΝΟΣ ΣΥΝΤΟΜΟ ΑΠΟΣΠΑΣΜΑ ΒΙΟΓΡΑΦΙΚΟΥ ΣΗΜΕΙΩΜΑΤΟΣ ΒΙΟΓΡΑΦΙΚΕΣ ΠΛΗΡΟΦΟΡΙΕΣ



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ΕΠΑΜΕΙΝΩΝΔΑΣ Β. ΤΣΙΑΝΟΣ ΣΥΝΤΟΜΟ ΑΠΟΣΠΑΣΜΑ ΒΙΟΓΡΑΦΙΚΟΥ ΣΗΜΕΙΩΜΑΤΟΣ ΒΙΟΓΡΑΦΙΚΕΣ ΠΛΗΡΟΦΟΡΙΕΣ Ο κος Επαμεινώνδας Τσιάνος του Βασιλείου γεννήθηκε στα Τρίκαλα Θεσσαλίας στις 29 Ιουνίου 1948 και έχει Ελληνική υπηκοότητα. Είναι έγγαμος, πατέρας 4 παιδιών και διανέμει στα Ιωάννινα. Είναι γνώστης της Αγγλικής και Γαλλικής γλώσσας. ΔΙΠΛΩΜΑΤΑ Πτυχίο της Ιατρικής Σχολής του Πανεπιστημίου Αθηνών, 30 Ιουνίου 1972. ιδάκτωρ της Ιατρικής Σχολής του Πανεπιστημίου Αθηνών, 28 Νοεμβρίου 1978. Υφηγητής Παθολογίας της Ιατρικής Σχολής του Πανεπιστημίου Ιωαννίνων, 7 Νοεμβρίου 1985. ΑΔΕΙΕΣ ΑΣΚΗΣΕΩΣ ΕΠΑΓΓΕΛΜΑΤΟΣ Άδεια ασκήσεως Ιατρικού Επαγγέλματος, Αύγουστος 1972. Τίτλος Ιατρικής Ειδικότητας Παθολογίας, 17 Νοεμβρίου 1978 (μετά από εξετάσεις). Certificate of Limited Registration as a Medical Practitioner (Central Medical Council, London, England 1980) Τίτλος συναφούς Ιατρικής Ειδικότητας Γαστρεντερολογίας, 19 Ιανουαρίου 1981. ΣΤΑΔΙΟΔΡΟΜΙΑ Ιανουάριος 1980 - Νοέμβριος του 1981 Clinical Fellow in Internal Medicine/Gastroenterology, Νοσοκομείο Royal Infirmary στο Manchester Αγγλίας Σεπτέμβριος 1988 Σεπτέμβριος 1989 εργάστηκα στο Ηπατο Γαστρεντερολογικό Τμήμα του Veterans Administration Medical Center, Washington DC σαν Visiting Researcher 1982-1986: Λέκτορας Παθολογίας, Ιατρική Σχολή, Πανεπιστήμιο Ιωαννίνων 1

1986-1990: Επίκουρος Καθηγητής Παθολογίας, Ιατρική Σχολή, Πανεπιστήμιο Ιωαννίνων. 1990-1996: Αναπληρωτής Καθηγητής Παθολογίας, Ιατρική Σχολή, Πανεπιστήμιο Ιωαννίνων 1996-2001: Καθηγητής Παθολογίας-Γαστρεντερολογίας της Ιατρικής Σχολής του Πανεπιστημίου Ιωαννίνων 2001- σήμερα : Καθηγητής Παθολογίας Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, Πανεπιστήμιο Ιωαννίνων 2002 σήμερα: ιευθυντής Α Πανεπιστημιακής Παθολογικής Κλινικής Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, Πανεπιστήμιο Ιωαννίνων 2012 σήμερα : ιευθυντής Πανεπιστημιακής Γαστρεντερολογικής Κλινικής, Τμήμα Ιατρικής, Σχολή Επιστημών Υγείας, Πανεπιστήμιο Ιωαννίνων ΔΙΔΑΚΤΟΡΙΚΟ ΕΡΓΟ Συμμετοχή σε ιδακτορικές ιατριβές: αριθ. 37 ΠΡΟΕΔΡΟΣ / ΜΕΛΟΣ ΔΙΟΙΚΗΤΙΚΩΝ ΣΥΜΒΟΥΛΙΩΝ ΚΑΙ ΕΠΙΤΡΟΠΩΝ ιευθυντής Παθολογικού Τομέα Ιατρικής Σχολής Πανεπιστημίου Ιωαννίνων ιευθυντής Α Παθολογικού Τομέα του Π.Γ.Ν.Ι. Πρόεδρος Ιατρικής Σχολής του Πανεπιστημίου Ιωαννίνων Πρόεδρος της Επιστημονικής Επιτροπής Φαρμάκων του Π.Γ.Ν.Ι. Μέλος στο Επιστημονικό Συμβούλιο του Π.Γ.Ν.Ι. Μέλος στην Επιστημονική Επιτροπή Έρευνας του Π.Γ.Ν.Ι. Μέλος στο Επιστημονικό Συμβούλιο του Πε.Σ.Υ.Π.Ηπείρου Δημοσιεύσεις 300 in International Journals 253 in Greek Journals 678 in Congresses 2

Citation Index h factor Editorial Board 4693 32 World Journal of Gastroenterology, European Journal of Internal Medicine, Annals of Gastroenterology, Reviewer American Journal of Gastroenterology,Gastroenterology, European Journal of Gastroenterology and Hepatology, Journal of Crohn s and Colitis, Nephrology Dialysis Transplantation Journal of Gastrointestinal and Liver Diseases, Digestion, Clinical Gastroenterology and Hepatology, World Journal of Gastroenterology Scandinavian Journal of Gastroenterology European Journal of Internal Medicine, Annals of Gastroenterology Fellow American Gastroenterology Association, European Board of Gastroenterology, European Crohn s and Colitis Organization ΔΗΜΟΣΙΕΥΣΕΙΣ ΑΡΘΡΩΝ ΣΤΟΝ ΔΙΕΘΝΗ ΙΑΤΡΙΚΟ ΤΥΠΟ 1. Burisch J, Weimers P, Pedersen N, Cukovic-Cavka S, Vucelic B, Kaimakliotis I, Duricova D, Bortlik M, Shonová O, Vind I, Avnstrøm S, Thorsgaard N, Krabbe S Andersen V, Dahlerup JF, Kjeldsen J, Salupere R, Olsen J, Nielsen KR, Manninen P, Collin P, Katsanos KH, Tsianos EV, Ladefoged K, Lakatos L, Ragnarsson G, Björnsson E, Bailey Y, O'Morain C, Schwartz D, Odes S, Valpiani D, Boni MC, Jonaitis L, Kupcinskas L, Turcan S, Barros L, Magro F, Lazar D, Goldis A, Nikulina I, Belousova E, Fernandez A, Sanroman L, Almer S, Zhulina Y, Halfvarson J, Arebi N, Diggory T, Sebastian S, Lakatos PL, Langholz E, Munkholm P; for the EpiCom-group. Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with Inflammatory Bowel Disease - An ECCO-EpiCom study. J CrohnsColitis. 2014 Feb 20. 3

2. Burisch J, Vegh Z, Pedersen N, Cuković-Čavka S, Turk N, Kaimakliotis I, Duricova D, Bortlik M, Shonová O, Thorsgaard N, Krabbe S, Andersen V, Dahlerup JF, Kjeldsen J, Salupere R, Olsen J, Nielsen KR, Manninen P, Collin P, Katsanos KH, Tsianos EV, Ladefoged K, Ragnarsson G, Björnsson E, Bailey Y, O'Morain C, Schwartz D, Odes S, Politi P, Santini A, Kiudelis G, Kupcinskas L, Turcan S, Magro F, Barros L, Lazar D, Goldis A, Nikulina I, Belousova E, Sanromán L, Martinez-Ares D, Almer S, Zhulina Y, Halfvarson J, Arebi N, Houston Y, Sebastian S, Langholz E, Lakatos PL, Munkholm P; for the EpiCom group. Health care and patients' education in a European inflammatory bowel disease inception cohort: An ECCO-EpiCom study. J Crohns Colitis. 2014 Jan 15. pii: S1873-9946(13)00471-6 3. Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D, Bortlik M, Shonová O, Vind I, Avnstrøm S, Thorsgaard N, Krabbe S, Andersen V, Dahlerup JF, Kjeldsen J, Salupere R, Olsen J, Nielsen KR, Manninen P, Collin P, Katsanos KH, Tsianos EV, Ladefoged K, Lakatos L, Ragnarsson G, Björnsson E, Bailey Y, O'Morain C, Schwartz D, Odes S, Giannotta M, Girardin G, Kiudelis G, Kupcinskas L, Turcan S, Barros L, Magro F, Lazar D, Goldis A, Nikulina I, Belousova E, Martinez-Ares D, Hernandez V, Almer S, Zhulina Y, Halfvarson J, Arebi N, Tsai HH, Sebastian S, Lakatos PL, Langholz E, Munkholm P; for the EpiCom-group. Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study. J Crohns Colitis. 2013 Dec 5. pii: S1873-9946(13)00410-8 4. Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D, Shonová O, Vind I, Avnstrøm S, Thorsgaard N, Krabbe S, Andersen V, Dahlerup Jens F, Kjeldsen J, Salupere R, Olsen J, Nielsen KR, Manninen P, Collin P, Katsanos KH, Tsianos EV, Ladefoged K, Lakatos L, Bailey Y, O'Morain C, Schwartz D, Odes S, Martinato M, Lombardini S, Jonaitis L, Kupcinskas L, Turcan S, Barros L, Magro F, Lazar D, Goldis A, Nikulina I, Belousova E, Fernandez A, Hernandez V, Almer S,Zhulina Y, Halfvarson J, Tsai HH, Sebastian S, Lakatos PL, Langholz E, Munkholm P; EpiCom Group. Initial disease course and treatment in an inflammatory bowel disease inception cohort in Europe: the ECCO-EpiCom cohort. Inflamm Bowel Dis. 2014 Jan;20(1):36-46 5. Cesarini M, Katsanos K, Papamichael K, Ellul P, Lakatos PL, Caprioli F, Kopylov U, Tsianos E, Mantzaris GJ, Ben-Horin S, Danese S, Fiorino G. Dose optimization is effective in ulcerative colitis patients losing response to infliximab: A collaborative multicentre retrospective study. Dig Liver Dis. 2014 Feb;46(2):135-9. doi: 10.1016 6. Katsanos AH, Kosmidou M, Giannopoulos S, Katsanos KH, Tsivgoulis G, Kyritsis AP, Tsianos EV. Cerebral arterial infarction in inflammatory bowel diseases. Eur J Intern Med. 2014 Jan;25(1):37-44 4

7. Papathanasopoulos A, Van Oudenhove L, Katsanos K, Christodoulou D, Tack J, Tsianos EV. Severity of fecal urgency and incontinence in inflammatory bowel disease: clinical, manometric and sonographic predictors. Inflamm Bowel Dis. 2013 Oct;19(11):2450-6 8. Pedersen N, Bortoli A, Duricova D, D Inca R, Panelli MR, Gisbert JP, Zoli G, López-Sanromán A, Castiglione F, Riegler G, Annese V, Gionchetti P, Prada A, Pont ED, Timmer A, Felley C, Shuhaibar M, Tsianos EV, Dejaco C, Baert FJ, Jess T, Lebech M, Hommes DW, Munkholm P; European Crohn-Colitis Organisation-ECCO-Study Group of Epidemiology Committee-EpiCom. The course of inflammatory bowel disease during pregnancy and postpartum: a prospective European ECCO-EpiCom Study of 209 pregnant women. Aliment Pharmacol Ther. 2013 Sep;38(5):501-12 9. Sebastian S, Hernández V, Myrelid P, Kariv R, Tsianos E, Toruner M, Marti- Gallostra M, Spinelli A, van der Meulen-de Jong AE, Yuksel ES, Gasche C, Ardizzone S, Danese S. Colorectal cancer in inflammatory bowel disease: results of the 3rd ECCO pathogenesis scientific workshop (I). J Crohns Colitis. 2014 Jan;8(1):5-18 10. Tsoumani A, Theopistos V, Katsanos K, Asproudis I, Tsianos EV. Treatment and non-treatment related ocular manifestations in patients with chronic hepatitis B or C. Eur Rev Med Pharmacol Sci. 2013 Apr;17(8):1123-31 11. Burisch J, Pedersen N, Cukovic-Cavka S, Brinar M, Kaimakliotis I, Duricova D, Shonová O, Vind I, Avnstrøm S, Thorsgaard N, Andersen V, Krabbe S, Dahlerup JF, Salupere R, Nielsen KR, Olsen J, Manninen P, Collin P, Tsianos EV, Katsanos KH, Ladefoged K, Lakatos L, Björnsson E, Ragnarsson G, Bailey Y, Odes S, Schwartz D, Martinato M, Lupinacci G, Milla M, De Padova A, D'Incà R, Beltrami M, Kupcinskas L, Kiudelis G, Turcan S, Tighineanu O, Mihu I, Magro F, Barros LF, Goldis A, Lazar D, Belousova E, Nikulina I, Hernandez V, Martinez-Ares D, Almer S, Zhulina Y, Halfvarson J, Arebi N, Sebastian S, Lakatos PL, Langholz E, Munkholm P; for the EpiCom-group. East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO- EpiCom inception cohort. Gut. 2013 12. Sigounas DE, Christodoulou DK, Tatsioni A, Katsanos KH, Baltayiannis G, Kappas A, Ioannidis JP, Tsianos EV. Pancreatitis potentially associated drugs as a risk factor for post-endoscopic retrograde cholangiopancreatography pancreatitis: a prospective cohort study. Pancreas. 2013 May;42(4):601-6. 13. Katsanos AH, Katsanos KH, Kosmidou M, Giannopoulos S, Kyritsis AP, Tsianos EV. Cerebral sinus venous thrombosis in inflammatory bowel diseases. QJM. 2013 May;106(5):401-13 14. Katsanos A, Asproudis I, Katsanos KH, Dastiridou AI, Aspiotis M, Tsianos EV Orbital and optic nerve complications of inflammatory bowel disease.. J Crohns Colitis. 2012 Oct 17 5

15. Kalambokis GN, Tsianos EV Systemic hemodynamic and renal effects of midodrine and octreotide in cirrhotic patients with ascites.. J Res Med Sci. 2011 Dec;16(12):1636-7 16. Kalambokis GN, Pappas K, Tsianos EV Terlipressin improves pulmonary pressures in cirrhotic patients with pulmonary hypertension and variceal bleeding or hepatorenal syndrome.. Hepatobiliary Pancreat Dis Int. 2012 Aug 15;11(4):434-7 17. Katsanos A, Asproudis I, Katsanos K, Tsianos EV On the probable association of adalimumab and diffuse retinopathy in a patient with Crohn's disease.. J Crohns Colitis. 2012 Jul 9 18. Katsanos KH, Tsianos VE, Tsianos EV Intolerance of folic acid in a patient receiving methotrexate for Crohn's disease.. J Crohns Colitis. 2012 Oct;6(9):960. 19. Katsanos KH, Siozopoulou V, Sigounas D, Tsianos VE, Christodoulou D, Mitsi V, Tsianos EV Adult-onset Still's disease preceding Crohn's disease.. J Crohns Colitis. 2012 Jun 13 20. Kalambokis GN, Mouzaki A, Rodi M, Tsianos EV. Rifaximin for the prevention of spontaneous bacterial peritonitis. World J Gastroenterol. 2012 Apr14;18(14):1700-2. 21. Katsanos KH, Voulgari PV, Tsianos EV. Inflammatory bowel disease and lupus: A systematic review of the literature. J Crohns Colitis. 2012 Apr 13. [Epub aheadof print]. 22. Kalambokis GN, Mouzaki A, Rodi M, Pappas K, Fotopoulos A, Xourgia X, Tsianos EV. Rifaximin Improves Systemic Hemodynamics and Renal Function in Patients With Alcohol-Related Cirrhosis and Ascites. Clin Gastroenterol Hepatol. 2012 Mar 3. 23. Ciancio A, Andreone P, Kaiser S, Mangia A, Milella M, Solà R, Pol S, Tsianos E, De Rosa A, Camerini R, McBeath R, Rizzetto M. Thymosin alpha-1 withpeginterferon alfa-2a/ribavirin for chronic hepatitis C not responsive to IFN/ribavirin: an adjuvant role? J Viral Hepat. 2012 Jan;19 Suppl 1:52-9. 24. Katz L, Gisbert JP, Manoogian B, Lin K, Steenholdt C, Mantzaris GJ, Atreja A, Ron Y, Swaminath A, Shah S, Hart A, Lakatos PL, Ellul P, Israeli E, Svendsen MN, van der Woude CJ, Katsanos KH, Yun L, Tsianos EV, Nathan T, Abreu M, Dotan I,Lashner B, Brynskov J, Terdiman JP, Higgins PD, Chaparro M, Ben- 6

Horin S. Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response. Inflamm Bowel Dis. 2012 Jan 31. doi:10.1002/ibd.22902. 25. Goulia P, Papadimitriou I, Machado MO, Mantas C, Pappa C, Tsianos E, Pavlidis N, Drosos AA, Carvalho AF, Hyphantis T. Does psychological distress vary between younger and older adults in health and disease? J Psychosom Res. 2012 Feb;72(2):120-8. 26. Katsanos KH, Tatsioni A, Natsi D, Sigounas D, Christodoulou DK, Tsianos EV. Recombinant human erythropoietin in patients with inflammatory bowel disease and refractory anemia: a 15-year single center experience. J Crohns Colitis. 2012 Feb;6(1):56-61. Epub 2011 Aug 17. 27. Tsianos EV, Katsanos KH, Tsianos VE. Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol. 2012 Jan 14;18(2):105-18. Review. 28. Katsanos KH, Voulgari PV, Goussia A, Oikonomou P, Christodoulou DK, Drosos AA, Tsianos EV. Coexistence of Crohn's disease in a patient with systemic lupus erythematosus. Rheumatol Int. 2012 Jan 15. 29. Tsianos EV, Katsanos KH, Tsianos VE. Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol. 2011 Dec 28;17(48):5246-59. Review. 30. Kalambokis GN, Mouzaki A, Rodi M, Tsianos EV. Rifaximin improves thrombocytopenia in patients with alcoholic cirrhosis in association with reduction of endotoxaemia. Liver Int. 2012 Mar;32(3):467-75. 31. Felekis T, Asproudis I, Katsanos K, Tsianos E. A case of nonarteritic anterior ischemic optic neuropathy of a male with family history of the disease after receiving sildenafil. Clin Ophthalmol. 2011;5:1443-5. Epub 2011 Oct 7. 32. Kalambokis GN, Tsianos EV. Rifaximin reduces endotoxemia and improves liver function and disease severity in patients with decompensated cirrhosis. Hepatology. 2012 Feb;55(2):655-6. 7

33. Katsanos KH, Tsianos EV. Piercing and Crohn's disease. J Crohns Colitis. 2011 Oct;5(5):502-3. 34. Katsanos KH, Tatsioni A, Pedersen N, Shuhaibar M, Ramirez VH, Politi P, Rombrechts E, Pierik M, Clofent J, Beltrami M, Bodini P, Freitas J, Mouzas I, Fornaciari G, Moum B, Lakatos PL, Vermeire S, Langholz E, Odes S, Morain CO,Stockbrügger R, Munkholm P, Tsianos EV. Cancer in inflammatory bowel disease 15years after diagnosis in a population-based European Collaborative follow-upstudy. J Crohns Colitis. 2011 Oct;5(5):430-42. Epub 2011 May 18. Erratum in: J Crohns Colitis. 2012 Feb;6(1):132-3. 35. Katsanos KH, Christodoulou D, Siozopoulou V, Eufimia B, Bali C, Fatouros M, Mitsi V, Tsianos EV. Silent ulcerative colitis adjacent to a regular sigmoid adenocarcinoma. Eur J Gastroenterol Hepatol. 2011 Oct;23(10):957-60 36. Kalambokis GN, Pappas K, Tsianos EV. Differential effects of terlipressin on pulmonary and systemic hemodynamics in patients with cirrhosis and pulmonary hypertension: an echo study. Angiology. 2012 Apr;63(3):199-205. 37. Kalambokis GN, Tsianos EV. Raised sympathetic activity and blood ammonia could increase sensitivity to infections in patients with cirrhosis and refractory ascites who are using beta-blockers. Hepatology. 2011 Oct;54(4):1486-7. 38. Katsanos KH, Zinovieva E, Lambri E, Tsianos EV. Eosinophilic-Crohn overlap colitis and review of the literature. J Crohns Colitis. 2011 Jun;5(3):256-61. 39. Kalambokis GN, Mouzaki A, Rodi M, Pappas K, Tsianos EV. Bacterial translocation attenuates the systemic hemodynamic improvement produced by terlipressin in patients with cirrhosis. Hepatology. 2011 Aug;54(2):743-4; authorreply 744. 40. Bassukas ID, Kosmidou M, Gaitanis G, Tsiouri G, Tsianos E. Patients with psoriasis are more likely to be treated for latent tuberculosis infection priorto biologics than patients with inflammatory bowel disease. Acta Derm Venereol. 2011 Jun;91(4):444-6. 8

41. Kalambokis GN, Fotopoulos A, Pappas K, Tsianos EV. Renal function impairment in patients with cirrhosis having pulmonary hypertension. Angiology. 2011 Oct;62(7):585-7. 42. Kalambokis GN, Mouzaki A, Rodi M, Pappas K, Korantzopoulos P, Tsianos EV. Serum interleukin 6 levels and cirrhosis-associated pulmonary hypertension. Angiology. 2011 May;62(4):344-5. 43. Christodoulou DK, Milionis HJ, Pappa P, Katsanos KH, Sigounas D, Florentin M, Elisaf M, Tsianos EV. Association of Helicobacter pylori infection with cardiovascular disease--is it just a myth? Eur J Intern Med. 2011 Apr;22(2):191-4. 44. Sigounas DE, Tatsioni A, Christodoulou DK, Tsianos EV, Ioannidis JP. New prognostic markers for outcome of acute pancreatitis: overview of reporting in 184 studies. Pancreas. 2011 May;40(4):522-32. 45. Katsanos KH, Stamou P, Tatsioni A, Tsianos VE, Zoumbas S, Kavvadia S, Giga A, Vagias I, Christodoulou DK, Tsianos EV; Northwest Greece IBD Study Group. Prevalence of inflammatory bowel disease related dysplasia and cancer in 1500 colonoscopies from a referral center in northwestern Greece. J Crohns Colitis. 2011 Feb;5(1):19-23. 46. Kalambokis G, Tsianos EV. Midodrine and furosemide-induced natriuresis in cirrhotics with ascites. Aliment Pharmacol Ther. 2011 Feb;33(3):415-6. 47. Mantzaris MD, Tsianos EV, Galaris D. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acidinduced lipotoxicity in liver cells. FEBS J. 2011 Feb;278(3):519-30. 48. Christodoulou DK, Sigounas DE, Katsanos KH, Dimos G, Tsianos EV. Small bowel parasitosis as cause of obscure gastrointestinal bleeding diagnosed by capsule endoscopy. World J Gastrointest Endosc. 2010 Nov 16;2(11):369-71. 49. Katsanos KH, Christodoulou DK, Kamina S, Maria K, Lambri E, Theodorou S, Tsampoulas K, Vasiliki M, Tsianos EV. Diagnosis and endoscopic treatment of esophago-bronchial fistula due to gastric heterotopy. World J Gastrointest Endosc. 2010 Apr 16;2(4):138-42. P 9

50. Kalambokis G, Tsianos EV. Thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count. Am J Gastroenterol. 2010 51. Kalambokis G, Tsianos EV. Pitfalls in the assessment of intrapulmonary shunt using lung perfusion scintigraphy in patients with cirrhosis. Liver Int. 2011 Jan;31(1):138-9; author reply 139-40. 52. Katsanos KH, Karetsos V, Tsianos EV. A family report of Crohn's disease in three children immigrating from Albania to Greece and review of the literature. J Crohns Colitis. 2010 Nov;4(5):582-5. Epub 2010 Jul 3. Review. 53. Papathanasopoulos AA, Katsanos KH, Tatsioni A, Christodoulou DK, Tsianos EV. Increased fatigability of external anal sphincter in inflammatory bowel disease: significance in fecal urgency and incontinence. J Crohns Colitis. 2010 Nov;4(5):553-60. 54. Papathanasopoulos AA, Katsanos KH, Tsianos EV. Late-onset ulcerative colitis presenting as filiform polyposis. J Crohns Colitis. 2010 Oct;4(4):488-9. Epub 2010 Aug 17. 55. Felekis T, Katsanos KH, Zois CD, Vartholomatos G, Kolaitis N, Asproudis I, Tsianos EV. Anterior ischemic optic neuropathy in a patient with Crohn's disease and aberrant MTHFR and GPIIIa gene variants. J Crohns Colitis. 2010 Oct;4(4):471-4. 56. Katsanos KH, Tsianos VE, Zois CD, Zioga H, Vagias I, Zervou E, Christodoulou DK, Tsianos EV; Northwest Greece IBD Study Group. Inflammatory bowel disease and hepatitis B and C in Western Balkans: a referral centre study and review of the literature. J Crohns Colitis. 2010 Oct;4(4):450-65. 57. Katsanos KH, Tsianos VE, Tsianos EV. Transient menorrhagia without adalimumab discontinuation in a patient with Crohn's disease. J Crohns Colitis. 2010 Sep;4(3):348. 58. Katsanos KH, Ignatiadou E, Sarandi M, Godevenos D, Asproudis I, Fatouros M, Tsianos EV. Fournier's gangrene complicating ulcerative pancolitis. J Crohns Colitis. 2010 Jun;4(2):203-6. 10

59. Zois CD, Katsanos KH, Kosmidou M, Tsianos EV. Neurologic manifestations in inflammatory bowel diseases: current knowledge and novel insights. J Crohns Colitis. 2010 Jun;4(2):115-24. 60. Van Assche G, Dignass A, Reinisch W, van der Woude CJ, Sturm A, De Vos M,Guslandi M, Oldenburg B, Dotan I, Marteau P, Ardizzone A, Baumgart DC, D'Haens G,Gionchetti P, Portela F, Vucelic B, Söderholm J, Escher J, Koletzko S, Kolho KL, Lukas M, Mottet C, Tilg H, Vermeire S, Carbonnel F, Cole A, Novacek G, ReinshagenM, Tsianos E, Herrlinger K, Oldenburg B, Bouhnik Y, Kiesslich R, Stange E, Travis S, Lindsay J; European Crohn's and Colitis Organisation (ECCO). The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations. J Crohns Colitis. 2010 Feb;4(1):63-101. 61. Kopylov U, Mantzaris GJ, Katsanos KH, Reenaers C, Ellul P, Rahier JF, Israeli E, Lakatos PL, Fiorino G, Cesarini M, Tsianos EV, Louis E, Ben-Horin S. The efficacy of shortening the dosing interval to once every six weeks in Crohn's patients losing response to maintenance dose of infliximab. Aliment Pharmacol Ther. 2011 Feb;33(3):349-57. 62. Aggelopoulou-Tiga P, Dimitroulopoulos D, Kaligeros K, Koutsounas S, Kouroumalis E, Diamanti H, Ionnidou P, Kountouras J, Papaioannou C, Dimopoulou M, Giannoulis G, Ketikoglou I, Protopapas A, Bassaris H, Delis V, Karatapanis S, Manolakopoulos S, Mimidis K, Nikolaou A, Thomopoulos K, Tzelas G, Tsianos E, Kardasi M, Perperas A. Pegylated interferon alfa-2b pen device and ribavirin treatment for patients with chronic hepatitis C: an evaluation of patient satisfaction. Eur J Gastroenterol Hepatol. 2010 Sep;22(9):1058-65. 63. Katsanos KH, Maliouki M, Tatsioni A, Ignatiadou E, Christodoulou DK, Fatouros M, Tsianos EV. The role of colonoscopy in the management of intestinal obstruction: a 20-year retrospective study. BMC Gastroenterol. 2010 Nov 8;10:130. 11

64. Kalambokis GN, Kosta P, Pappas K, Tsianos EV. Haemodynamic and renal effects of tadalafil in patients with cirrhosis. World J Gastroenterol. 2010 Oct1;16(39):5009-10. 65. Kalambokis G, Tsianos EV. Lung perfusion scan is not superior to contrastenhanced echocardiography for the diagnosis of the hepatopulmonary syndrome in chronic liver disease. Eur J Gastroenterol Hepatol. 2010 Nov;22(11):1387-8 66. Christodoulou DK, Tsianos EV. Role of endoscopic retrograde cholangiopancreatography in pancreatic diseases. World J Gastroenterol. 2010 Oct 14;16(38):4755-61. 67. Kalambokis G, Baltayiannis G, Tsiouris S, Pappas K, Kokkinou P, Fotopoulos A, Tsianos EV. Scintigraphic evaluation of intrapulmonary shunt in normoxemic cirrhotic patients and effects of terlipressin. Hepatol Res. 2010 Oct;40(10):1015-21 68. Kalambokis G, Tsianos EV. Endotoxaemia in the pathogenesis of cytopenias in liver cirrhosis. Could oral antibiotics raise blood counts? Med Hypotheses. 2011 Jan;76(1):105-9. 69. Kalambokis G, Tsiouris S, Tsianos EV, Baltayiannis G, Pakou B, Fotopoulos A. Effects of terlipressin and somatostatin on liver and thorax blood volumes in patients with cirrhosis. Liver Int. 2010 Oct;30(9):1371-8. 70. Kalambokis G, Tsianos EV. Refractory ascites: can it be defined only by the response to furosemide and spironolactone? Liver Int. 2010 Oct;30(9):1394; author reply 1395-6 71. Zois CD, Baltayiannis GH, Bekiari A, Goussia A, Karayiannis P, Doukas M,Demopoulos D, Mitsellou A, Vougiouklakis T, Mitsi V, Tsianos EV. Steatosis andsteatohepatitis in postmortem material from Northwestern Greece. World JGastroenterol. 2010 Aug 21;16(31):3944-9. PubMed PMID: 72. Kalambokis GN, Pappas K, Baltayiannis G, Katsanou A, Tsianos EV. Effects of terlipressin on water excretion after oral water load test in nonazotemic 12

cirrhotic patients with ascites without hyponatremia. Scand J Gastroenterol. 2010 Dec;45(12):1509-15. 73. Leuschner UF, Lindenthal B, Herrmann G, Arnold JC, Rössle M, Cordes HJ, Zeuzem S, Hein J, Berg T; NASH Study Group. High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebocontrolled trial. Hepatology. 2010 Aug;52(2):472-9. 74. Juillerat P, Pittet V, Mottet C, Felley C, Gonvers JJ, Vader JP, Burnand B, Froehlich F, Wolters FL, Stockbrügger RW, Michetti P; EC-IBD Group. Appropriateness of early management of newly diagnosed Crohn's disease in a European population-based cohort. Scand J Gastroenterol. 2010 Dec;45(12):1449-56. 75. Psofaki V, Kalogera C, Tzambouras N, Stephanou D, Tsianos E, Seferiadis K, Kolios G. Promoter methylation status of hmlh1, MGMT, and CDKN2A/p16 in colorectal adenomas. World J Gastroenterol. 2010 Jul 28;16(28):3553-60. 76. Kalambokis GN, Pappas K, Tsianos EV. Effect of alpha1-blockade with doxazosinin pulmonary hypertension associated with cirrhosis. Scand J Gastroenterol. 2010 77. Katsanos KH, Tatsioni A, Tsakiris V, Christodoulou D, Tsianos EV. Helicobacter pylori is a major public health priority in western Balkans: an endoscopy referral center experience. Eur J Intern Med. 2010 Aug;21(4):306-9. 78. Liberopoulos EN, Florentin M, Elisaf MS, Mikhailidis DP, Tsianos E. Fenofibrate in primary biliary cirrhosis: a pilot study. Open Cardiovasc Med J. 2010 Apr 28;4:120-6. 79. Katsanos KH, Briasoulis E, Tsekeris P, Batistatou A, Bai M, Tolis C, Capizzello A, Panelos I, Karavasilis V, Christodoulou D, Tsianos EV. Randomized phase II exploratory study of prophylactic amifostine in cancer patients who receive radical radiotherapy to the pelvis. J Exp Clin Cancer Res. 2010 Jun 10;29:68. 13

80. Katsanos KH, Koulouras V, Nakos G, Tsianos EV. Successful management of full-length obstructing esophageal bezoars in an intensive care unit. Intensive Care Med. 2010 Jul;36(7):1280-1. 81. Katsanos KH, Katopodis KP, Kosmidou M, Siamopoulos KC, Tsianos EV. Leptospira interrogans icterohaemorrhagiae in a patient with Crohn's disease. Inflamm Bowel Dis. 2010 Nov;16(11):1824-5. 82. Hyphantis T, Antoniou K, Tomenson B, Tsianos E, Mavreas V, Creed F. Is the personality characteristic "impulsive sensation seeking" correlated to differences in current smoking between ulcerative colitis and Crohn's disease patients? Gen Hosp Psychiatry. 2010 Jan-Feb;32(1):57-65. 83. Christou L, Kalambokis G, Bai M, Kamina S, Tsianos EV. Splenic marginal zone lymphoma in a patient with chronic hepatitis B. J Gastrointestin Liver Dis. 2009 Dec;18(4):511-2. Erratum in: J Gastrointestin Liver Dis. 2010 Mar;19(1):118. 84. Odes S, Vardi H, Friger M, Esser D, Wolters F, Moum B, Waters H, Elkjaer M, Bernklev T, Tsianos E, O'Morain C, Stockbrügger R, Munkholm P, Langholz E. Clinical and economic outcomes in a population-based European cohort of 948 ulcerative colitis and Crohn's disease patients by Markov analysis. Aliment Pharmacol Ther. 2010 Apr;31(7):735-44. 85. Kalambokis G, Christou L, Siaplaoura E, Tsianos EV. Polymyalgia rheumatic associated with neck surgery. South Med J. 2009 Nov;102(11):1190-86. Christou L, Economou G, Zikou AK, Saplaoura K, Argyropoulou MI, Tsianos EV. Acute Haemophilus parainfluenzae endocarditis: a case report. J Med Case Rep. 2009 Jul 16;3:7494 87. Katsanos KH, Christodoulou DK, Zervou E, Babameto A, Kraja B, Hyphantis H, Karetsos V, Tsonis G, Basho J, Resuli BF, Tsianos EV. Hepatitis B remains a major health priority in Western Balkans: results of a 4-year prospective Greek-Albanian collaborative study. Eur J Intern Med. 2009 Nov;20(7):698-702. 14

88. Kosmidou M, Gaitanis G, Nomikos K, Zioga A, Katsanos K, Bassukas ID, Tsianos E. Severe rosacea in a patient on infliximab for ulcerative colitis: pathophysiological considerations. Acta Derm Venereol. 2009;89(5):522-3. 89. Felekis T, Katsanos K, Christodoulou D, Asproudis I, Tsianos EV. Reversible bilateral optic neuritis after Infliximab discontinuation in a patient with Crohn's disease. J Crohns Colitis. 2009 Sep;3(3):212-4. Epub 2009 May 2 90. Katsanos KH, Saougos V, Kosmidou M, Doukas M, Kamina S, Asproudis I, Tsianos EV. Sjogren's syndrome in a patient with ulcerative colitis and primary sclerosing cholangitis: Case report and review of the literature. J Crohns Colitis. 2009 Sep;3(3):200-3. Epub 2009 Apr 21. PubMed PMID: 21172271. 91. Kalambokis GN, Christou L, Tsianos EV. Multiple myeloma presenting with an acute bacterial infection. Int J Lab Hematol. 2009 Aug;31(4):375-83. Epub 2009 Apr 17. Review. 92. Papadopoulos V, Protopapas A, Tsianos E, Mimidis K. Three-year follow-up of pegylated interferon alfa-2b as monotherapy or in combination with lamivudine in patients with HBeAg-negative chronic hepatitis B. Scand J Gastroenterol. 2009;44(8):1021-2. 93. Kapetanos D, Christodoulou D, Chatzizisi O, Sigounas D, Vasiliou K, Stavropoulou E, Katodritou E, Kokozidis G, Kiriazis G, Kitis G, Tsianos E. Randomized study of the effect of pentoxifylline or octreotide on serum levels of TNF-alpha and IL-6 after endoscopic retrograde cholangiopancreatography. Eur J Gastroenterol Hepatol. 2009 May;21(5):529-33. 94. Marcellin P, Bonino F, Lau GK, Farci P, Yurdaydin C, Piratvisuth T, Jin R, Gurel S, Lu ZM, Wu J, Popescu M, Hadziyannis S; Peginterferon alfa-2a in HBeAgnegative Chronic Hepatitis B Study Group. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology. 2009 Jun;136(7):2169-2179.e1-4. 95. Hyphantis TN, Tomenson B, Bai M, Tsianos E, Mavreas V, Creed F. Psychological distress, somatization, and defense mechanisms associated with 15

quality of life in inflammatory bowel disease patients. Dig Dis Sci. 2010 Mar;55(3):724-32 96. Katsanos KH, Christodoulou D, Kalampokis G, Tsianos EV, Theodorou SJ, Tsampoulas C, Xeropotamos N. Radiological evidence of double inferior vena cava in two patients with liver function abnormalities. Eur J Intern Med. 2009 Jan;20(1):e17. 97. Tsianos EV, Katsanos K. Do we really understand what the immunological disturbances in inflammatory bowel disease mean? World J Gastroenterol. 2009 Feb 7;15(5):521-5. Review.. 98. Katsanos K, Ignatiadou E, Markouizos G, Doukas M, Siafakas M, Fatouros M, Tsianos EV. Non-toxic megacolon due to transverse and sigmoid colon volvulus in a patient with ulcerative colitis. J Crohns Colitis. 2009 Feb;3(1):38-41. 99. Kalambokis G, Economou G, Nikas S, Bai M, Lampri E, Kosta P, Tsianos EV. Concurrent development of spontaneous pyomyositis due to Staphylococcus epidermidis and Kikuchi-Fujimoto disease. Intern Med. 2008;47(24):2139-43. 100. Zois CD, Baltayiannis GH, Karayiannis P, Tsianos EV. Systematic review: hepatic fibrosis - regression with therapy. Aliment Pharmacol Ther. 2008 Nov 15;28(10):1175-87. 101. Christodoulou DK, Katsanos KH, Makrydimas G, Tsanadis G, Tsianos EV. Peripheral parenteral nutrition in protracted hyperemesis gravidarum-- report of two cases and a literature review. Acta Gastroenterol Belg. 2008 Apr- Jun;71(2):259-62. 102. Kalambokis GN, Tsianos EV. Vasoconstrictor therapy for patients with cirrhosis with ascites but without hepatorenal syndrome. Hepatology. 2008 Aug;48(2):686 103. Felekis T, Katsanos K, Kitsanou M, Trakos N, Theopistos V, Christodoulou D, Asproudis I, Tsianos EV. Spectrum and frequency of ophthalmologic manifestations in patients with inflammatory bowel disease: a prospective single-center study. Inflamm Bowel Dis. 2009 Jan;15(1):29-34. 16

104. Baltayiannis G, Baltayiannis N, Tsianos EV. Suppressors of cytokine signaling as tumor repressors. Silencing of SOCS3 facilitates tumor formation and growth in lung and liver. J BUON. 2008 Apr-Jun;13(2):263-5. Review. 105. Sherman M, Yurdaydin C, Simsek H, Silva M, Liaw YF, Rustgi VK, Sette H, Tsai N, Tenney DJ, Vaughan J, Kreter B, Hindes R; AI463026 Benefits of Entecavir for Hepatitis B Liver Disease (BEHoLD) Study Group. Entecavir therapy for lamivudine-refractory chronic hepatitis B: improved virologic, biochemical, and serology outcomes through 96 weeks. Hepatology. 2008 Jul;48(1):99-108. 106. Høie O, Aamodt G, Vermeire S, Bernklev T, Odes S, Wolters FL, Riis L, Politi P, Tsianos EV, Butrón M, Stockbrügger RW, Munkholm P, Vatn M, Moum B; on behalf of the European Collaborative study group of Inflammatory Bowel Disease (EC-IBD). Serological markers are associated with disease course in ulcerative colitis. A study in an unselected population-based cohort followed for 10 years. J Crohns Colitis. 2008 Jun;2(2):114-122. 107. Kalambokis G, Theodorou A, Kosta P, Tsianos EV. Multiple myeloma presenting with pyomyositis caused by community-acquired methicillinresistant Staphylococcus aureus: report of a case and literature review. Int J Hematol. 2008 Jun;87(5):516-9. 108. Christou L, Kalambokis G, Tsianos EV. Weil's disease in a patient with chronic viral hepatitis and history of alcohol abuse. Intern Med. 2008;47(10):933-7. Epub 2008 May 15. PubMed PMID: 18480577. 109. Elefsiniotis IS, Pavlidis C, Ketikoglou I, Koutsounas S, Scarmeas N, Pantazis KD, Moulakakis A, Tsianos EV. Patient's age modifies the impact of the proposed predictors of sustained virological response in chronic hepatitis C patients treated with PEG-interferon plus ribavirin. Eur J Intern Med. 2008 Jun;19(4):266-70. Epub 2008 Jan 15. PubMed PMID: 18471675. 110. Anagnostopoulos GK, Stefanou D, Arkoumani E, Karagiannis J, Paraskeva K, Chalkley L, Habilomati E, Tsianos E, Agnantis NJ. 17

Immunohistochemical expression of cell-cycle proteins in gastric precancerous lesions. J Gastroenterol Hepatol. 2008 Apr;23(4):626-31. 111. Kalambokis G, Korantzopoulos P, Nikas SA, Theodorou A, Tsianos EV. Significant improvement of portopulmonary hypertension after 1-week terlipressin treatment. J Hepatol. 2008 Apr;48(4):678-80. 112. Kalambokis G, Theodorou A, Tsianos EV. Disseminated intravascular coagulation associated with cytomegalovirus infection in a patient with hepatitis C virus cirrhosis. Hepatol Res. 2008 Jun;38(6):635-7 113. Anagnostopoulos GK, Stefanou D, Arkoumani E, Chalkley L, Karagiannis J, Paraskeva K, Mathou N, Dellaporta E, Tsianos E, Agnantis NJ. Expression of Bax protein in gastric carcinomas. A clinicopathological and immunohistochemical study. Acta Gastroenterol Belg. 2007 Jul-Sep;70(3):285-9. 114. Papathanasopoulos AA, Katsanos KH, Christodoulou DK, Nikas S, Tsianos EV. An unusual case of Crohn's disease with unresponsive pleural exudates. Is Crohn's disease finally a systemic immunological disorder? J Crohns Colitis. 2007 Dec;1(2):116-21. 115. Katsanos K, Cavalier E, Ferrante M, Van Hauwaert V, Henckaerts L, Schnitzler F, Katsaraki A, Noman M, Vermeire S, Tsianos EV, Rutgeerts P, Chapelle JP, Van Assche G. Intravenous iron therapy restores functional iron deficiency induced by infliximab. J Crohns Colitis. 2007 Dec;1(2):97-105. Epub 2007 Sep 27. 116. Odes S, Vardi H, Friger M, Wolters F, Hoie O, Moum B, Bernklev T, Yona H, Russel M, Munkholm P, Langholz E, Riis L, Politi P, Bondini P, Tsianos E, Katsanos K, Clofent J, Vermeire S, Freitas J, Mouzas I, Limonard C, O'Morain C, Monteiro E, Fornaciari G, Vatn M, Stockbrugger R; on behalf of the European Collaborative Study Group on Inflammatory Bowel Disease. Effect of phenotype on health care costs in Crohn's disease: A European study using the Montreal classification. J Crohns Colitis. 2007 Dec;1(2):87-96 18

117. Christodoulou DK, Haber G, Beejay U, Tang SJ, Zanati S, Petroniene R, Cirocco M, Kortan P, Kandel G, Tatsioni A, Tsianos E, Marcon N. Reproducibility of wireless capsule endoscopy in the investigation of chronic obscure gastrointestinal bleeding. Can J Gastroenterol. 2007 Nov;21(11):707-14. 118. Christodoulou D, Christou L, Zervou E, Katsanos K, Kitsanou M, Tsianos EV. Antiplatelet antibodies in patients with chronic viral hepatitis receiving interferon-alpha. Hepatogastroenterology. 2007 Sep;54(78):1761-5. 119. Kalambokis G, Christou L, Stefanou D, Arkoumani E, Tsianos EV. Association of liver cirrhosis related IgA nephropathy with portal hypertension. World J Gastroenterol. 2007 Nov 21;13(43):5783-6. 120. Economou M, Filis G, Tsianou Z, Alamanos J, Kogevinas A, Masalas K, Petrou A, Tsianos EV. Crohn's disease incidence evolution in North-western Greece is not associated with alteration of NOD2/CARD15 variants. World J Gastroenterol. 2007 Oct 14;13(38):5116-20 121. Kapetanos D, Kokozidis G, Christodoulou D, Mistakidis K, Sigounas D, Dimakopoulos K, Kitis G, Tsianos EV. A randomized controlled trial of pentoxifylline for the prevention of post-ercp pancreatitis. Gastrointest Endosc. 2007 Sep;66(3):513-8 122. Christou L, Economou M, Economou G, Kolettis TM, Tsianos EV. Characteristics of ascitic fluid in cardiac ascites. Scand J Gastroenterol. 2007 Sep;42(9):1102-5. 123. Kapetanos D, Kokozidis G, Christodoulou D, Mistakidis K, Dimakopoulos K, Katodritou E, Kitis G, Tsianos EV. Case series of transpancreatic septotomy as precutting technique for difficult bile duct cannulation. Endoscopy. 2007 Sep;39(9):802-6. 124. Katsanos KH, Vermeire S, Christodoulou DK, Riis L, Wolters F, Odes S, Freitas J, Hoie O, Beltrami M, Fornaciari G, Clofent J, Bodini P, Vatn M, Nunes PB, Moum B, Munkholm P, Limonard C, Stockbrugger R, Rutgeerts P, Tsianos EV; EC-IBD Study Group. Dysplasia and cancer in inflammatory bowel disease 19

10 years after diagnosis: results of a population-based European collaborative follow-up study. Digestion. 2007;75(2-3):113-21. 125. Economou M, Milionis H, Filis S, Baltayiannis G, Christou L, Elisaf M, Tsianos E. Baseline cholesterol is associated with the response to antiviral therapy in chronic hepatitis C. J Gastroenterol Hepatol. 2008 Apr;23(4):586-91. 126. Kalambokis G, Tsianos EV. Treatment of hepatic hydrothorax with vasoconstrictor drugs. Scand J Gastroenterol. 2007 Apr;42(4):534 127. Economou MS, Filis S, Vienna H, Christodoulou D, Christou L, Tsianos EV.Treatment and retreatment in patients with chronic hepatitis C: 10 years clinical practice in a single centre. Liver Int. 2007 Apr;27(3):340-6. 128. Wolters FL, Joling C, Russel MG, Sijbrandij J, De Bruin M, Odes S, Riis L, Munkholm P, Bodini P, Ryan B, O'Morain C, Mouzas IA, Tsianos E, Vermeire S, Monteiro E, Limonard C, Vatn M, Fornaciari G, Rodriguez D, Groot W, Moum B, Stockbrügger RW; European Collaborative Study Group On Inflammatory Bowel Disease (EC-IBD). Treatment inferred disease severity in Crohn's disease: evidence for a European gradient of disease course. Scand J Gastroenterol. 2007 Mar;42(3):333-44. 129. Papatheodoridis GV, Goulis J, Christodoulou D, Manolakopoulos S, Raptopoulou M, Andrioti E, Alexandropoulos N, Savvidou S, Papachristou A, Zervou E, Seferiadis K, Kousidou P, Vogiatzakis E, Tsianos E. High prevalence of elevated liver enzymes in blood donors: associations with male gender and central adiposity. Eur J Gastroenterol Hepatol. 2007 Apr;19(4):281-7 130. Diakou MC, Liberopoulos EN, Mikhailidis DP, Tsianos EV, Burroughs AK, Elisaf MS. Pharmacological treatment of non-alcoholic steatohepatitis: the current evidence. Scand J Gastroenterol. 2007 Feb;42(2):139-47. Review. 131. Odes S, Friger M, Vardi H, Claessens G, Bossuyt X, Riis L, Munkholm P, Wolters F, Yona H, Hoie O, Beltrami M, Tsianos E, Katsanos K, Mouzas I, Clofent J, Monteiro E, Messori A, Politi P, O'Morain C, Limonard C, Russel M, Vatn M, Moum B, Stockbrugger R, Vermeire S; European Collaborative Study Group on Inflammatory Bowel disease. Role of ASCA and the NOD2/CARD15 20