ΣΠΟΥΔΕΣ ΚΑΙ ΣΤΟΙΧΕΙΑ ΕΠΑΓΓΕΛΜΑΤΙΚΗΣ ΔΡΑΣΤΗΡΙΟΤΗΤΑΣ

Βασίλειος Βαργεμέζης Καθηγητής Νεφρολογίας ΔΠΘ Δ/ντής Παν. Νεφρολογικής Κλινικής ΠΓΝΑ ΣΠΟΥΔΕΣ ΚΑΙ ΣΤΟΙΧΕΙΑ ΕΠΑΓΓΕΛΜΑΤΙΚΗΣ ΔΡΑΣΤΗΡΙΟΤΗΤΑΣ 1975 Ιατρική Σχολή Αριστοτελείου Πανεπιστημίου Θεσσαλονίκης 1979 Ειδικότητα Εσωτερικής Παθολογίας Ιατρική Σχολή ΑΠΘ 1981 Διδακτορική Διατριβή Ιατρική Σχολή ΑΠΘ 1984 Ειδικότητα Νεφρολογίας Ιατρική Σχολή ΑΠΘ Ειδική Εκπαίδευση- Μετεκπαίδευση: Συνεχής Φορητή Περιτοναϊκή Κάθαρση Μεταμόσχευση Νεφρού Ξένες γλώσσες: Αγγλικά- Ιταλικά 1985 Επίκουρος Καθηγητής Νεφρολογίας ΔΠΘ 1989 Αναπληρωτής Καθηγητής Νεφρολογίας ΔΠΘ 1993 Καθηγητής Νεφρολογίας ΔΠΘ 1987 μέχρι και σήμερα Διευθυντής Πανεπιστημιακής Νεφρολογικής Κλινικής ΔΠΘ Υπεύθυνος λειτουργίας και κλινικού έργου της Πανεπιστημιακής Νεφρολογικής Κλινικής, των Μονάδων Αιμοκάθαρσης, Περιτοναϊκής Κάθαρσης, Πλασμαφαίρεσης και των εργαστηρίων Ανοσοϊστοχημείας - Ιστοσυμβατότητας Νεφρού και Παθοφυσιολογίας Νεφρού- Μεταβολικών Νοσημάτων Ερευνητικά και Διδακτικά ενδιαφέροντα Έρευνα και διδασκαλία σε προπτυχιακό και μεταπτυχιακό επίπεδο Διδασκαλία: -Νεφρολογία: προπτυχιακό μάθημα 5ου έτους σπουδών, Εαρινού εξαμήνου Τμήματος Ιατρικής -Εκπαίδευση ειδικευομένων ιατρών στην Νεφρολογία (6 θέσεις ειδικευομένων για πλήρη 4ετή ειδίκευση) -Επιβλέπον Καθηγητής και μέλος Συμβουλευτικών και Εξεταστικών επιτροπών Διδακτορικών Διατριβών - Οργάνωση Σεμιναρίων Συνεχιζόμενης Εκπαίδευσης στη Νεφρολογία Ερευνητικό έργο: -Με αντικείμενο την κλινική νεφρολογία, περιτοναϊκή κάθαρση, αιμοκάθαρση, αναιμία -Με αντικείμενο την ιατρική εκπαίδευση -Στα πλαίσια ευρωπαϊκών πολυκεντρικών μελετών με συμμετοχή στις κεντρικές επιτροπές αποφάσεων (steering committee) -Ανάπτυξη και εφαρμογή τηλεματικής υπηρεσίας για την κατ οίκον παρακολούθηση ασθενών

που υποβάλλονται σε περιτοναϊκή κάθαρση. -Ανάλυση χώρου και απαιτήσεων για την κατ οίκον υποστήριξη περιτοναϊκής κάθαρσης -Έρευνα, εφαρμογή και διδασκαλία μεθόδων αξιολόγησης τηλεματικών υπηρεσιών για την κατ οίκον φροντίδα ασθενών Μέλος Επιστημονικών Επιτροπών 2000-2007 Αναπληρωτής Πρόεδρος στο Τμήμα Μοριακής Βιολογίας και Γενετικής του ΔΠΘ 2002-2006 Εκπρόσωπος του ΔΠΘ στην ένωση των Πανεπιστημίων της Μεσογείου Community of Mediterranean Universities ( CUM) 2006-2010 Διευθυντής Τομέα Γενικής Παθολογίας ΔΠΘ 2002-2003 Πρόεδρος της επιτροπής Προγράμματος Σπουδών της Ιατρικής Σχολής του ΔΠΘ μέχρι και σήμερα 2003 Πρόεδρος Επιστημονικού Συμβουλίου ΠΓΝΑ Μέλος της επιτροπής διασύνδεσης της CUM με την ένωση των Πανεπιστημίων της Μαύρης Θάλασσας (Black Sea University Foundation) 2003-2006 Μέλος της Επιτροπής Ερευνών του ΔΠΘ 2004 μέχρι και σήμερα Μέλος της επιτροπής Προγράμματος Σπουδών της Ιατρικής Σχολής του ΔΠΘ 2005 μέχρι και σήμερα Υπεύθυνος Γραφείου Εκπαίδευσης Ιατρικού Τμήματος ΔΠΘ 2006 μέχρι και σήμερα Μέλος της Επιτροπής Ηθικής και Δεοντολογίας ΔΠΘ 2007 μέχρι και σήμερα 2007 μέχρι και σήμερα Πρόεδρος Επιτροπής Εκπαίδευσης Ελληνικής Νεφρολογικής Εταιρείας Πρόεδρος Επιστημονικής Επιτροπής των Συνεδρίων και Εκπαιδευτικών Σεμιναρίων της Ελληνικής Νεφρολογικής Εταιρείας 2007 Μέλος Επιτροπής Σύνταξης Κώδικα Ηθικής και Δεοντολογίας ΔΠΘ 2008 Μέλος της Επιτροπής Σύνταξης Προτάσεων Προγραμματισμού Τμήματος Ιατρικής του 4ετούς Ακαδημαϊκού - Αναπτυξιακού προγράμματος ΔΠΘ 2008 μέχρι και σήμερα Μέλος 7μελούς Ομάδας Εσωτερικής Αξιολόγησης, Τμήμα Ιατρικής, ΔΠΘ 2007 Μέλος της Επιστημονικής Επιτροπής της Ειδικής Προγράμματος Special Track on Technology Enhanced Learning in Medical Education στα πλαίσια του Διεθνούς Συνεδρίου CBMS 2007: The 20th IEEE International Symposium on Computer-Based Medical Systems, Maribor, Slovenia, June 20-22,2007 1990 μέχρι και σήμερα Πρόεδρος Οργανωτικής Επιτροπής περισσότερων από 10 Εκπαιδευτικών Σεμιναρίων με διεθνή συμμετοχή Μέλος Επιστημονικών Εταιρειών Πρόεδρος Ελληνικής Νεφρολογικής Εταιρείας (ΕΝΕ) 2004-2006

European Renal Association /European Dialysis Transplant Association International Society of Peritoneal Dialysis Κριτής σε Επιστημονικά Περιοδικά και Συνέδρια Ελληνική Νεφρολογία Nature Clinical Practice Nephrology Renal Failure Nephrology (Carlton) Nephron Clinical Practice Συμμετοχή σε Επιστημονικές Επιτροπές Διεθνών Κλινικών Μελετών Phase II Study ΒΑ 16260 Steering Committee member Roche Hellas Ανοιχτή, πολυκεντρική μελέτη (Φάσης ΙΙ) πολλαπλών δόσεων για τη διερεύνηση της αποτελσματικότητας και ασφάλειας υποδόριων ενέσεων RO 50-3821 χορηγούμενων σε διαφορετικά χρονικά διαστήματα σε ασθενείς με χρόνια αναιμία νεφρικής αιτιολογίας που υποβάλλονται σε αιμοκάθαρση. ΚΩΔΙΚΟΣ ΕΓΚΡΙΣΗΣ ΕΟΦ: Αα-ΚΔ-70/01 Phase III Study BA16736 Steering Committee member, Roche Hellas Ανοιχτή, πολυκεντρική μελέτη (Φάσης ΙΙΙ) της αποτελεσματικότητας των υποδορίων ενέσεων ερυθροποιητίνης βήτα σε ασθενείς με αναιμία λόγω χρόνιας νεφρικής ανεπάρκειας που υποβάλλονται σε περιτοναϊκή κάθαρση, και οι οποίοι μεταβαίνουν από προηγούμενο δοσολογικό σχήμα δύο έως τριών ενέσεων την εβδομάδα σε σχήμα μιας ένεσης την εβδομάδα ή από προηγούμενο δοσολογικό σχήμα μιας ένεσης της εβδομάδας σε σχήμα μιας ένεσης κάθε δύο εβδομάδες. ΚΩΔΙΚΟΣ ΕΓΚΡΙΣΗΣ ΕΟΦ: Αα-ΚΔ-4296 MAP 5/2006 Managing Mineral Metabolism: Advances in Practice (MAP).SHIRE Ερευνητικά έργα: 1. «ΠΕΡΚΑ Κατ Οίκον Υποστήριξη Περιτοναϊκής Κάθαρσης», Χρηματοδότηση: Επιχειρησιακού Προγράμματος Ανατολικής Μακεδονίας Θράκης 2000-2006 «Κοινοπραξίες Έρευνας και Τεχνολογικής Ανάπτυξης σε τομείς Εθνικής Προτεραιότητας», Διάρκεια:2006-2008, Επιστημονικός Υπεύθυνος 2. Αναμόρφωση Προπτυχιακού Προγράμματος Σπουδών Τμήματος Ιατρικής ΔΠΘ- ΕΠΕΑΕΚ ΙΙ Πράξεις ΕΚΤ για Αναμόρφωση Προπτυχιακών Προγραμμάτων Σπουδών, Υπουργείο Εθνικής Παιδείας και Θρησκευμάτων. Διάρκεια:2003-2008, Επιστημονικός Υπεύθυνος 3. Εξοπλισμός για Υποστήριξη Πράξεων ΕΚΤ Αναμόρφωσης Προπτυχιακού Προγράμματος Σπουδών Τμήματος Ιατρικής, ΔΠΘ- ΕΠΕΑΕΚ ΙΙ Πράξεις ΕΤΠΑ για υποστήριξη Πράξεων ΕΚΤ, Υπουργείο Εθνικής Παιδείας και Θρησκευμάτων. Διάρκεια:2003-2005, Επιστημονικός Υπεύθυνος 4. Μέλος της ομάδας εργασίας του ΔΠΘ στο έργο: «meducator - Multi-type Content Repurposing and Sharing in Medical Education», econtentplus 2008, Information Society and Media Directorate-General, EC, 2009-2012, 5. Μέλος της ομάδας εργασίας ΙntraMEDnet - A Mediterranean Research and Higher Education Intranet in Medical and Biological Sciences ARCHIMED Interreg III, Strand B, ERDF, European Community. Διάρκεια:2006-2007, Ανάδοχος: Κοινοπραξία Παν. Κύπρου, Νοσ. Πάφου, ΔΠΘ, ΑΠΘ, Παν. Πάτρας, Παν. Νάπολης 6. Υλοποίηση έργου «Πρότυπο σύστημα κατ οίκον υποστήριξης νεφρικής ανεπάρκειας (ΕΠΙΧΕΙΡΗΣΕΙΣ / ΕΦΑΡΜ/0308/66)», Δέσμη Προγραμμάτων για Έρευνα, Τεχνολογική Ανάπτυξη και Καινοτομία 2008. Διάρκεια: 014/02/09 έως 31/07/10, Επιστημονικός Υπεύθυνος

στην κοινοπραξία. Δημοσιεύσεις σε διεθνή επιστημονικά περιοδικά με αντικείμενο την ιατρική εκπαίδευση 1. E. Kaldoudi, A. Chatzopoulou, V. Vargemezis, Adopting the STARE-HI Guidelines for the Evaluation of Home Care Telehealth Applications: An Interpretive Approach, The Journal on Information Technology in Healthcare 2009; 7(5): 293 303 2. E. Kaldoudi, A. Chatzopoulou, V. Vargemezis, An Interpretive Approach in the Evaluation of Homecare Telematics Interventions, PETRA2009: 2nd International Conference on Pervasive Technologies Related to Assistive Environments, Corfu, Greece, June 9-13, 2009. 3. E. Kaldoudi, V. Vargemezis, Telecare in Peritoneal Dialysis - Current trends and design considerations,international Workshop on Home telemonitoring, and its status in Cyprus, Greece, and Italy, Thessaloniki, September 1, 2008. 4. E. Kaldoudi, P. Passadakis, S. Panagoutsos, V. Vargemezis, Homecare Telematics for Peritoneal Dialysis,Journal on Information Technology in Healthcare, vol. 5(6), pp. 372-378, 2007. 5. E. Kaldoudi, P. Passadakis, S. Panagoutsos, V. Vargemezis, Home Care Telematics for Peritoneal Dialysis: Field Analysis and Design Considerations, ICICTH2007: 5th International Conference on Information & Communication Technologies in Health, Samos, July 5-7, 2007 6. Μ. Papaioakeim, E. Kaldoudi, V. Vargemezis, K. Simopoulos, Confronting the Problem of Ever Expanding Core Knowledge and the Necessity of Handling Overspecialized Disciplines in Medical Education, ITAB 2006: IEEE International Special Topic Conference on Information Technology in Biomedicine, Ioannina, Greece, October 26-28, 2006 7. E. Kaldoudi, V. Vargemezis, K. Simopoulos, Information and Communication Technologies in Medical Undergraduate Education, Journal for Quality of Life Research, vol. 2(1), pp. 33-37, 2004. 8. E. Kaldoudi, V. Vargemezis, Κ. Simopoulos, Information and Communication Technologies in Medical Undergraduate Education, Proceedings of ICICHT 2004: 2nd International Conference on Information Communication Technologies in Health, pp. 129-134, Samos, Greece, July 8-10, 2004. Δημοσιεύσεις ερευνητικού έργου 93 Δημοσιευμένες μελέτες σε ξενόγλωσσα ιατρικά περιοδικά: PubMed - indexed for MEDLINE και SCOPUS 1. Lialiaris T, Mavromatidou P, Digkas E, Passadaki T, Mpountoukas P, Panagoutsos S, Vargemezis V. Chromosome Instability in Patients with Chronic Renal Failure.Genet Test Mol Biomarkers. 2009 Nov 23. 2. Iordanidou M, Tavridou A, Petridis I, Arvanitidis KI, Christakidis D,Vargemezis V, Manolopoulos VG. The serotonin transporter promoter polymorphism (5-HTTLPR) is associated with type 2 diabetes. Clin Chim Acta. 411 (3-4), pp 167-171, 2009 Nov 2. 3. Digkas E, Kareli D, Chrisafi S, Passadaki T, Mantadakis E, Hatzimichail A,Vargemezis V, Lialiaris T. Attenuation of cytogenetic effects by erythropoietin in human lymphocytes in vitro and P388 ascites tumor cells in vivo treated with irinotecan (CPT-11). Food Chem Toxicol. 2009 Oct 9. 48(1), pp.242-249 4. Bacharaki D, Thodis E, Passadakis P, Kantartzi K, Kriki P, Vargemezis V. Comparative in vitro Study of Different Peritoneal Dialysis Solutions on Cytokine Production by Peripheral

Blood Mononuclear Cells. Nephron Clin Pract. 2009 Sep 3;113(4):c321-c329. [Epub ahead of print] PubMed PMID: 19729968. 5. Thodis E, Kriki P, Kakagia D, Passadakis P, Theodoridis M, Mourvati E, Vargemezis V. Rigorous Vibrio vulnificus soft tissue infection of the lower leg in a renal transplant patient managed by vacuum therapy and autologous growth factors. J Cutan Med Surg. 2009 Jul- Aug;13(4):209-14. 6. Vargemezis V, Liakopoulos V, Kriki P, Panagoutsos S, Leontsini M, Passadakis P, Thodis E. Pivotal Role of Paricalcitol in the Treatment of Calcific Uremic Arteriolopathy in the Presence of a Parathyroid Adenoma. Am J Kidney Dis. 2009.May 27. 55(1), pp.144-147 7. Kriki P, Thodis E, Deftereos S, Panagoutsos S, Theodoridis M, Kantartzi K, Mourvati E, Prassopoulos P, Passadakis P, Vargemezis V. A tumor-like manifestation of extrapulmonary tuberculosis in a hemodialysis patient. Clin Nephrol. 2009 Jun;71(6):714-8. 8. Oreopoulos DG, Thodis E, Passadakis P, Vargemezis V. Home dialysis as a first option: a new paradigm. Int Urol Nephrol. 2009;41(3):595-605. Epub 2009 May 9. Review. PubMed PMID: 19430923. 9. Pierides A, Voskarides K, Athanasiou Y, Ioannou K, Damianou L, Arsali M, Zavros M, Pierides M, Vargemezis V, Patsias C, Zouvani I, Elia A, Kyriacou K, Deltas C. Clinicopathological correlations in 127 patients in 11 large pedigrees, segregating one of three heterozygous mutations in the COL4A3/ COL4A4 genes associated with familial haematuria and significant late progression to proteinuria and chronic kidney disease from focal segmental glomerulosclerosis. Nephrol Dial Transplant. 2009 Sep;24(9):2721-9. Epub 2009 Apr 8. PubMed PMID:19357112. 10. Kantartzi K, Panagoutsos S, Kokkinou V, Passadakis P, Vargemezis V. Unexpectedly high incidence of brucellosis in one university dialysis unit of North East Greece. Nephrol Dial Transplant. 2009 Jun;24(6):2003-4. Epub 2009 Mar 30. PubMed PMID: 19332870. 11. Fellström BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Grönhagen-Riska C, De Lima JJ, Lins R, Mayer G,McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Süleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wüthrich RP, Gottlow M, Johnsson E, Zannad F; AURORA Study Group. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. N Engl J Med. 2009 Apr 2;360(14):1395-407. Epub 2009 Mar 30. PubMed PMID: 19332456. 12. Courcoutsakis N, Souftas V, Thodis I, Vargemezis V, Prassopoulos P. Sclerosing peritonitis. Intern Med. 2008;47(15):1441-2. Epub 2008 Aug 1. PubMed PMID: 18670153. 13. Hutchison AJ, Laville M; SPD405-313 Lanthanum Study Group. Switching to lanthanum carbonate monotherapy provides effective phosphate control with a low tablet burden. Nephrol Dial Transplant. 2008 Nov;23(11):3677-84. Epub 2008 Jun 24. PubMed PMID: 18577536; PubMed Central PMCID: PMC2568007. 14. Aspris AK, Thodi CD, Balatsouras DG, Thodis ED, Vargemezis V, Danielides V. Auditory brainstem responses in patients under treatment of hemodialysis. Ren Fail. 2008;30(4):383-90. PubMed PMID: 18569911.

15. Fatouros IG, Pasadakis P, Sovatzidis A, Chatzinikolaou A, Panagoutsos S, Sivridis D, Michailidis I, Douroudos I, Taxildaris K, Vargemezis V. Acute exercise may exacerbate oxidative stress response in hemodialysis patients. Nephron Clin Pract. 2008;109(2):c55-64. Epub 2008 Jun 18. PubMed PMID: 18560239. 16. Georgiadis GS, Lazarides MK, Panagoutsos SA, Kantartzi KM, Lambidis CD, Staramos DN, Vargemezis VA. Surgical revision of complicated false and true vascular access-related aneurysms. J Vasc Surg. 2008 Jun;47(6):1284-1291. PubMed PMID: 18514844. cited 1 time 17. Antoniadi G, Eleftheriadis T, Liakopoulos V, Kakasi E, Kartsios C, Passadakis P, Vargemezis V. Effect of one-year oral alpha-tocopherol administration on the antioxidant defense system in hemodialysis patients. Ther Apher Dial. 2008 Jun;12(3):237-42. PubMed PMID: 18503702. 18. Kaldoudi, E., Bamidis, P., Papaioakeim, M., Vargemezis, V. Problem-based learning via Web 2.0 technologies (2008) Proceedings - IEEE Symposium on Computer-Based Medical Systems, art. no. 4562023, pp. 391-396. Cited 3 times. 19. Theodoridis M, Passadakis P, Kriki P, Gioka T, Panagoutsos S, Mourvati E, Thodis E, Kantartzi K, Vargemezis V. The alteration of dialysate cancer antigen 125 concentration under a biocompatible bicarbonate peritoneal dialysis solution and the preservation of the mesothelial cell viability. Ren Fail. 2008;30(2):161-7. PubMed PMID: 18300115. cited 2 times 20. Iordanidou M, Tavridou A, Vasiliadis MV, Arvanitidis KI, Petridis J, Christakidis D, Vargemezis V, Bougioukas G, Manolopoulos VG. The -759C/T polymorphism of the 5-HT2C receptor is associated with type 2 diabetes in male and female Caucasians. Pharmacogenet Genomics. 2008 Feb;18(2):153-9. PubMed PMID: 18192901. cited 2 times 21. Macdougall, I.C., Walker, R., Provenzano, R., de Alvaro, F., Locay, H.R., Nader, P.C., Locatelli, F., Dougherty, F.C., Beyer, U., Altieri, P., Amato, M., Annerstedt, M., Balducci, A., Barre, P., Breen, C., Brown, E., Burgos-Calderon, R., Carpenito, G., Choukroun, G., Craver, L., Culleton, B., de Alvaro, F., Deferrari, G., del Pino y Pino, M., Dragoun, G.-P., Durand, D., Esnault, V., Evenepoel, P., Faller, B., Fine, A., Fischer, D., Formica, M., Frei, U., Frenken, L., Golper, T., Hagen, C., Hahn, K., Harris, K., Imbasciati, E., Jacquot, C., Jolly, S., Kaysen, G., Kerr, P., Kessler, M., Kopyt, N., Kovesdy, C., Kraut, J., Kwan, J., Lafayette, R., Laville, M., Levin, A., Locatelli, F., Locay, H.R., Lok, C., Macdougall, I.C., MacPhee, I., Franco, J.E.M., Castelao, A.M., McMahon, A., Ruiz, E.M., Muirhead, N., Murphy, S., Nader, P.C., Nassar, G.M., Noble, S., Papadakis, G., Papadakis, I., Penfield, J., Pichette, V., Provenzano, R., Pylypchuk, G., Risler, T., Puyol, D.R., Rosansky, S., Sakellariou, G., Schmidt, R., Siamopoulos, K., Solomon, R., Spinowitz, B., Stegmayr, B., Suranyi, M., Tam, P., Tobe, S., Vargemezis, V., Vela, C., Villa, G., Walker, R., Warr, K., Wijeyesinghe, C., Woitas, R., Zoccali, C. C.E.R.A. corrects anemia in patients with chronic kidney disease not on dialysis: Results of a randomized clinical trial (2008) Clinical Journal of the American Society of Nephrology, 3 (2), pp. 337-347. Cited 9 times 22. Klinger M, Arias M, Vargemezis V, Besarab A, Sulowicz W, Gerntholtz T, Ciechanowski K, Dougherty FC, Beyer U. Efficacy of intravenous methoxy polyethylene glycol-epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trial. Am J Kidney Dis. 2007 Dec;50(6):989-1000. PubMed PMID: 18037099. cited 10 times

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