Effect of shengjiang powder on protection of myocardial injury in patients with sepsis

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1 Journal of Clinical Medicine in Practice NYHA I ctni BNP LVEF E /A 2 ctni BNP P < P < LVEF E /A NYHA P < R 631 A DOI /jcmp Effect of shengjiang powder on protection of myocardial injury in patients with sepsis QIAN Fenghua ZHAO Lei SHEN Mengwen WANG Jin XI Yao GUO Jian Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai ABSTRACT Objective To observe the clinical effect of shengjiang powder on protection of myocardial injury in patients with sepsis. Methods A total of 60 patients with myocardial injury caused by sepsis toxic heat syndrome were randomly divided into western control group and traditional Chinese and western medicine treatment group. Western medicine control group was given routine treatment of western medicine while traditional Chinese medicine and western medicine treatment group was given western medicine combined with shengjiang powder on the basis of control group. The TCM syndrome score curative effect of TCM syndrome the NYHA grading the levels of troponin I ctni brain natriuretic peptide BNP left ventricular ejection fraction LVEF and the ratio of mitral flow velocity and the expansion of the early peak atrial systolic blood flow velocity E /A were detected and compared before and after treatment. Results After treatment the TCM syndrome score serum ctni and BNP improved significantly in both groups P < and Chinese and western medicine treatment group were significantly better than the western medicine control group P < After treatment the LVEF E /A and NYHA grading improved significantly in both groups P < Conclusion Shengjiang powder combined with routine western medicine therapy can effectively reduce TCM syndrome score in myocardial injury toxic heat flourishing syndrome patients with sepsis improve the curative effect of TCM syndrome and reduce the myocardial damage of patients. KEY WORDS sepsis myocardial injury shengjiang powder E - mail smileqian1975@ qq. com

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4 10 20 P = NYHAⅠ NYHAⅡ ~ Ⅳ NYHAⅡ NYHA Ⅱ 76. 5% 13 / % 14 /16 2 P = / CI 16 CO 1999 Andrew 25% I ctni BNP 4 - / ctni BNP 1 GALLEY H F. Oxidative stress and mitochondrial dysfunction in sepsis J. Br J Anaesth

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