Progress on oral colon specific drug delivery system

HTML
DOWNLOAD

Μέγεθος: px

Εμφάνιση ξεκινά από τη σελίδα:

Download "Progress on oral colon specific drug delivery system"

Φωτεινή Μαυρίδης
8 χρόνια πριν
Προβολές:

1 R944 A Progress on oral colon specific drug delivery system ZHOU Jie 1 2 ZHU Xiao-ning 1 2 ZHANG Yi 1 2 ZHOU Xin 1 2 CUI Yuan-lu Reasearch Center of Traditional Chinese Medicine Tianjin University of Chinese Medicine Tianjin China 2 Tianjin State Key Laboratory of Modern Chinese Medicine Tianjin China Abstract Oral colon specific drug delivery system has gained more attention from investigators in recent years since it can improve local drug concentration and reduce dosage and side effects. The design principle preparation technology and in vitro / vivo evaluation methods of oral colon specific drug delivery system were summarized in this paper to provide theoretical basis and reference for the development of oral colon specific drug delivery system. Key words colon specific drug delivery system preparation technology evlaution methods ph 2012ZX rhea @ 163. com tju. edu. cn 390 ph

2 1. 1 ph 16 HPMC ph EC HPMC γ- ph ph 5-5-ASA ph 1. 3 Gao 8 CPVA-g-PSSS MTZ ph ph = 1 Jeong 17 ph = 7. 4 EC HPMC 9 HPMCAS 10 ph -Eudragit100 PEG EC EC ph ph 18 Kovačič 11 ph 1. 2 McLeod 20 - HPMC Time Clock 12 5-ASA 21 Wilding Stella ASA Amal 22 Wu 15 HPMC 5- L- α- β- HPMC Zhiz 23 β- MTZ MTZ 391

3 9. 5% 43. 6% Maestrelli h 100% Riberio 31 / 24 β- Jose 32 /ph β- 25 Eudragit S β- ph = Miloslava / Jerry 38 Dhawan 28 ph Dai ph Mirela 29 ph Eudragit FS 30 D ph / ph 392

4 ph Kotla 40 Sharna 41 89% 2. 2 γ X Ursekar 47 CPM 9 h 24 h 1. M. 90% Maurer C 15 2 PINTO JF. Site-specific drug delivery systems within the gastrointestinal tract from the mouth to the colon J. Int J Pharm N RABI KOV M BAUTZOV T GAJDZIOK J et al. Coated FITC - chitosan pellets containing rutin intended for the treatment of inflammatory bowel disease In vitro characteristics and in vivo evaluation J. Int J Pharm J J KUMAR P MISHRA B. Colon targeted drug delivery systems-an overview J. Curr Drug Deliv QURESHI AM MOMIN M RATHOD S et al. Colon targeted drug delivery system a review on current approaches J. Indian 3 J Pharm GAO B FANG L MEN J et al. Preparation of grafted microspheres CPVA-g-PSSS and studies on their drug-carrying and colon-specific drug delivery properties J. Mat Sci Eng C mtor J

5 lon-specific drug delivery system J. Pharm Dev Tech J KOVACIC B VRECER F PLANINSEK O. Design of a drug delivery system with biomodal ph dependent release of a poorly soluble drug J. Die Pharmaize-An Int J Pharm Sci POZZI F FURLANI P GAZZANIGA A et al. The time clock system a new oral dosage form for fast and complete release of drug after a predetermined lag time J. J Control Release WILDING IR DAVIS S POZZI F et al. Enteric coated timed release systems for colonic targeting J. Int J Pharm STEED KP HOOPER G MONTI N et al. The use of pharmaeoseintigraphy to focus the development strategy for a novel 5-ASA colon targeting system TIME CLOCK system J. J Control Release WU B SHUN N WEI X et al. Characterization of 5-fluorouracil release from hydroxy propylmethyl cellulose compression-coated tablets J. Pharm Dev Technol MAESTRELLI F CIRRI M CORTI G et al. Development of enteric-coated calcium pectinate microspheres intended for colonic drug delivery J. Eur J Pharm Biopharm RIBEIRO L ANA CS MARGARITA D et al. Pectin-coated chitosan-ldh bionanocomposite beads as potential systems for colon-targeted drug delivery J. Int J Pharm JOSE S PREMA MT CHACKO AJ et al. Colon specific chitosan microspheres for chronotherapy of chronic stable angina J. Colloids Surf B Biointerfaces D J β- J D DI PG ZEMA L WILSON DI et al. Optimisation and scale-up 16. J. of a highly-loaded 5-ASA multi-particulate dosage form using a JEONG YI OHNO T HU Z et al. Evaluation of an intestinal pressure controlled colon delivery capsules prepared by a dipping method J. J Control Release LAUTENSCHLAGER C SCHMIDT C FISCHER D et al. Drug delivery strategies in the therapy of inflammatory bowel disease J. Adv Drug Deliv Rev STELLA VJ HIMMELSTEIN KJ. Prodrug and site specific drug delivery J. J Med Chem MCLEOD AD FRIEND DR THOMA NT. Glucocorticoid-dextran conjugates as potential prodrugs for colon specific deliveryhydrolysis in rat gastrointestinal tract contents J. J Pharm Sci TAKADA K. Controlled-release preparations U. S. Patent P E1-KAMEL AH ABDEL-AZIZ AA FATANI AJ et al. Oral colon targeted delivery systems for treatment of inflammatory bowel diseases Synthesis in vitro and in vivo assessment J. Int J Pharm ZHIZ W BENP L PEIP M et al. Preparation and in vitro evaluation of macrocyclic metronidazole J. Incl Phenom Macrocycl Chem SHAH N SHAH T AMIN A. Polysaccharides a targeting strategy for colonic drug delivery J. Expert Opin Drug Deliv factorial approach J. Eur J Pharm Sci JERRY Y. Stimuli-responsive drug delivery system J. Adv Drug Deliv Rev DAI J WU S JIANG W et al. Facile synthesis of pectin coated Fe3O4 nanospheres by the sonochemical method J. J Magn Magn Mater KOTLA NG GULATI M SINGH SK et al. Facts fallacies and future of dissolution testing of polysaccharide based colon-specific drug delivery J. J Controll Release SHARNA R RAWAL R K MALHOTRA M et al. Design synthesis and ex-vivo release studies of colon-specific polyphosphazene-anticancer drug conjugates J. Bioorg Med Chem SUBHABROTA M SOUVIK R SUBHADEEP C. Preparation and gamma scintigraphic evaluation of colon specific pellets of ketoprofen prepared by powder layering technology J. Daru J RISHABH S DEEPESH K KAMLA P. Colonic luminal surface retention of meloxicam microsponges delivered by erosion based colon-targeted matrix tablet J. Int J Pharm J J SABAA MW. Chitosan-g-Copolymers Synthesis Properties and 46. J Application M / /Polysaccharide Based Graft Copolymers. 47 URSEKAR BM SONI PS DATE AA et al. Characterization of Springer Berlin Heidelberg soy polysaccharide and its in vitro and in invo evaluation for ap- 27. plication in colon drug delivery J. AAPS Pharm Sci Tech D DHAWAN S SINGLA AK SINHA VR. Evaluation of mucoadhesive properties of chitosan microspheres prepared by different methods J. AAPS Pharm Sci Tech MIRELA FR ADRIANO VR ADONILSONDOS RF et al. A MAURER MJ SCHELLEKENS RC WUTZKE KD et al. Isotope-labelled urea to test colon drug delivery devices in vivo principles calculations and interpretations J. Isotopes Environ Health Stud ph /enzyme-responsive polymer film consisting of Eudragit FS 30 D and arabinoxylane as a potential material formulation for co- /

Σχετικά έγγραφα

The Study and Application of Film Coated Pellets in the Prep aratio n of Pharmaceutic s

2008 32 2 76 76 2008, Vol. 32, No. 2,, 3 (, 510080) [ ],, [ ] ; ; ; [ ] R94419 [ ] A [ ]1001-5094 (2008) 02-0076 - 06 The Study and Application of Film Coated Pellets in the Prep aratio n of Pharmaceutic