267 Vol. 36, pp. 267 277, 2008 : 20 8 12 20 1 1990 45 49 1 1972 1989 Stage I, II 1 2 Stage I, II 20 3 18 2006 59.0 20 32.9 5..4 1 4 2 1994 5 1999 3cm 6 4cm 69
268 1 Breast Cancer 2008; 15: 3-4 4cm 2007 74 2 18 6 7 2 2 3 CT, MRI 2 2007 70
269 CT, MRI 4 MR CT MRI MRI MRI MRI MR micro coil 0.1 mm MR 8 9 MR 3 MR micro coil MR MR 4 1 3 MR RI 95 2003 21.5 4,427 20,620 10 2006 56.2 5 4 RI RI 3 RI 11 12 RI RI 71
270 4 MR 5 Breast Cancer 2008;15: 3-4 2006 60 4 RI RI 2 2000 5 2008 4 2006 73.1 6 15.3 57.8 72
271 6 down staging 1 13 National Surgical Adjuvant Breast and Bowel Project NSABP B-18 AC 7 NSABP B-18 J Natl Cancer Inst Monogr 2001; 30: 96 102 4 7 AC AC 1 14 EROTC 10902 CEF 15 73
272 2 NSABP B-18 AC AC 67.8 59.8 14 1 EROTC 10902 48.9 246 57 23 15 NSABP B-18 AC AC NSABP B-27 T AC AC AC AC T AC 3 8 AC AC T 61 63 2 16 3 pcr NSABP B-18 pcr 10 14 pcr NSABP B-27 AC AC T pcr 9.8 18.7 2 16 pcr 17 17 4 18 1 AC AC NSBP B-18 J Nat 1 Cancer Inst Monogr 2001; 30: 96 102. AC AC 67.8 59.8 8 NSABP B-27 J Clin Oncol 2003; 21: 4165 4174. 2 AC AC T ccr, pcr NSABP B-27 J Clin Oncol 2003; 21: 4165 4174 74
273 3 2007 9 10 2007 419 93 22.2 93 70 75.2 74.2 3 5 19 MR 9 10 MR 5 vanishing, scar, concentrated, mosaic, branching 11 pcr Vanishing 100 concentrated 6.9 mosaic 0 mosaic 56.5 75
274 11 MR 4 branching 47.1 mosaic branching 53.9, 50.0 4 Branching mosaic MR 12 76
275 13 2007 14 12 2007 7 2 30 419 16 16 30 53 3 13 6 77
276 14 MR 75 1 Fisher B, Redmond C, Poisson R, Margolese R, Wolmark N, Wickerham L, Fisher E, Deutsch M, Caplan R, Pich Y, et al: Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med 1989; 320: 822 828. 2 Veronesi U, Salvadori B, Luini A, Greco M, Saccozzi R, del Vecchio M et al: Breast conservation is a safe method in patients with small cancer of breast. Long-term results of three randomised trials on 1973 patients. Eur J Cancer 1995; 31A: 1574 1579. 3 Fisher B, Anderson S, Bryant J, Margolese G, Deutsch M, Fisher ER, et al: Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002; 347: 1233 1241. 4 Sonoo H, Noguchi S; Academic Committee of the Japanese Breast Cancer Society: Results of questionnaire survey on breast cancer surgery in Japan 2004 2006. Breast Cancer 2008; 15: 3 4. 5 1994 61999 : 1999; 6 7: Quadrantectomy 54; 2000: 145 150 8 Kanemaki Y, Kurihara Y, Itoh D, Kamijo K, Nakajima Y, Fukuda M, Van Cauteren M: MR mammary ductography using a microscopy coil for assessment of intraductal lesions. AJR 2004; 182: 1340 1342. 9 Kanemaki Y, Kurihara Y, Okamoto K, Nakajima Y, Fukuda M, Maeda I, Akiyama F: Ductal carcinoma in situ: correlations between high-resolution magnetic resonance imaging and histopathology. Radiat Med 2007; 25: 1 7. 10 Sonoo H, Fukuda M: The Japanese Breast Cancer Society: Results of questionnaires concerning breast cancer surgery in Japan 1980 2003. Breast Cancer 2005; 12: 1 2. 11 Morrow M, Rademaker AW, Bethke KP, Talamonti MS, Dawes LG, Clauson J, Hansen N. : Learning sentinel node biopsy: results of a prospective randomized trial of two techniques. Surgery 1999; 126: 714 720. 12 Cody HS 3rd, Fey J, Akhurst T, Fazzari M, Mazumdar M, Yeung H, Yeh SD, Borgen PI: Complementarity of blue dye and isotope in sentinel node localization for breast cancer: univariate and multivariate analysis of 966 procedures. Ann Surg Oncol 2001; 8: 13 19. 78
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