Γεώργιος Ανδρικόπουλος, Δ/ντής Καρδιολογικής Κλινικής, ΓΝΑ «Ερρίκος Ντυνάν»
Δήλωση συμφερόντων Ο ομιλητής έχει λάβει ερευνητικά κονδύλια, αμοιβές για συμμετοχή σε συμβουλευτικά σώματα και αμοιβές για ομιλίες σε εκπαιδευτικά σεμινάρια, στην Ελλάδα και στο εξωτερικό, από τις κάτωθι φαρμακευτικές εταιρείες: AstraZeneca, Bard, Bayer Healthcare, Boehringer Ingelheim, Boston Scientific, Bristol Myers Squibb, ELPEN, Galenica, Medtronic, Menarini, MSD, Pfizer, Sanofi, Servier, StJude, Vianex.
Proportion of global deaths associated with atrial fibrillation in 2010. Chugh S et al. Circulation 2014;129:837-847 Copyright American Heart Association, Inc. All rights reserved.
Incidence of atrial fibrillation: 1990 and 2010. Chugh S et al. Circulation 2014;129:837-847 Copyright American Heart Association, Inc. All rights reserved.
Mortality associated with atrial fibrillation: 1990 to 2010. Chugh S et al. Circulation 2014;129:837-847 Copyright American Heart Association, Inc. All rights reserved.
Disability-adjusted life-years (DALYs) related to atrial fibrillation. Chugh S et al. Circulation 2014;129:837-847 Copyright American Heart Association, Inc. All rights reserved.
ΕΠΙΠΟΛΑΣΜΟΣ ΚΟΛΠΙΚΗΣ ΜΑΡΑΜΡΥΓΗΣ ΣΤΟΝ ΕΛΛΗΝΙΚΟ ΠΛΗΘΥΣΜΟ (>14 ΕΤΩΝ) ΔΕΔΟΜΕΝΑ ΑΠΟ ΤΟ ΠΡΟΓΡΑΜΜΑ ΠΡΟΛΗΨΗΣ ΤΟΥ ΕΛΙΚΑΡ Συνολικός αριθμός συμμετεχόντων: 44.956 άτομα > 14 ετών Δεδομένα για ΚΜ από 2011 ως 2013: 6970 ερωτηματολόγια πληθυσμός > 14 ετών: 9148309 (84,80%) ΕΛΙΚΑΡ μη δημοσιευμένα δεδομένα 2014
All 182 678 individuals (2% of the Swedish population 2% of the Swedish population) with a diagnosis of AF at a Swedish hospital between July, 1, 2005, and December 1, 2008, were identified through the Swedish National Hospital Discharge Register (HDR). Circulation. 2012 May 15;125(19):2298 307
ΑΝΤΙΠΗΚΤΙΚΗ ΑΓΩΓΗ ΣΤΟΝ ΕΛΛΗΝΙΚΟ ΠΛΗΘΥΣΜΟ ΔΕΔΟΜΕΝΑ ΑΠΟ ΤΟ ΠΡΟΓΡΑΜΜΑ ΠΡΟΛΗΨΗΣ ΤΟΥ ΕΛΙΚΑΡ Συνολικός αριθμός συμμετεχόντων: 44.956 Δεδομένα για ΚΜ από 2011 ως 2013: 6970 ερωτηματολόγια ΕΛΙΚΑΡ μη δημοσιευμένα δεδομένα 2014
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study MANAGE AF centers and investigators Principal investigators: Professor Panos Vardas, Dr. George Andrikopoulos Participating centers and investigators Attica 1. Alexandra University Hospital, Athens: Principal Investigator: K. Vemmos. Co investigator: P. Savvari 2. Evagelismos General Hospital, Athens: Principal Investigator: M. Efraimidis. Co investigators: A. Sideris, L. Lioni 3. Henry Dunant Hospital, Athens: Principal Investigator: G. Theodorakis. Co investigator: I. Rassias 4. 7 th IKA Hospital, Athens: Principal Investigator: G. Kazianis. 5. Red Cross Hospital, Athens: Principal Investigator: A. Katsivas. Co investigator: S. Kourouklis 6. Sismanogleio General Hospital, Athens: Principal Investigator: M. Papavasileiou 7. KAT General Hospital, Athens: Principal Investigator: D. Babalis. Co investigator: I. Tzinieris 8. Laiko University Hospital, Athens: Principal Investigator: C. Oikonomou. Co investigator: D. Papadopoulos 9. Thriasio General Hospital, Elefsina: Principal Investigator: C. Olympios. Co investigator: V. Karydas 10. Konstantopoulio General Hospital, Athens: Principal Investigator: S. Patsilinakos 11. Hygeia Hospital, Athens: Principal Investigator: A. Pipilis. Co investigator: G. Tsakonas 12. Euroclinic Hospital of Athens: Principal Investigator: D. Richter. Co investigators: D. Sakellariou, G. Goumas. Thessaloniki 13. AHEPA University Hospital, Thessaloniki: Principal Investigator: V. Vasilikos. Co investigator: G. Dakos 14. 2nd IKA Hospital, Thessaloniki: Principal Investigator: C. Kyrpizidis. 15. Hippokration General Hospital, Thessaloniki: Principal Investigator: N. Fragakis Northern Greece 16. Chios General Hospital: Principal Investigator: S. Garoufalis. Co investigators: G. Georgiopoulos, G. Voutas, A. Kosti. 17. Komotini General Hospital: Principal Investigator: A. Gotsis, Co investigator: A. Risgits 18. Serres General Hospital: Principal Investigator: P. Kelebekoglou. 19. University Hospital of Alexandroupolis: Principal Investigator: D. Stakos 20. Ptolemaida General Hospital: Principal Investigator: S. Lampropoulos 21. Edessa General Hospital: Principal Investigator: P. Makridis. Co investigator: I. Karantoumanis 22. Kavala General Hospital: Principal Investigator: D. Symeonidis. Co investigator: N. Vatkalis Central Greece 23. Volos General Hospital: Principal Investigator: T. Tsaknakis. Co investigators: I. Nastas, N. Nikoloulis 24. Halkida General Hospital: Principal Investigator: I. Mantas Southern Greece 25. University Hospital of Heraklion: Principal Investigator: P. Vardas. Co investigator: E. Kallergis 26. Venizeleio General Hospital, Heraklion: Principal Investigator: L. Ploumidis. Co investigator: E. Lamrogiannakis 27. Chania General Hospital: Principal Investigator: A. Pras. Co investigator: E. Michelakis 603 consecutive patients with any type of AF over 18 years of age, presenting at the emergency departments or outpatient clinics of 27 different centers, were included in our study
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Andrikopoulos G., et al. On behalf of the MANAGE AF AF study investigators. Submitted 2014
MANAGE AF AF Study RAFTING
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Andrikopoulos G., et al. On behalf of the MANAGE AF AF study investigators. Submitted 2014
MANAGE AF AF Study RAFTING
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Table 4. Prevalence of stroke risk factors components components of CHADS 2 and CHA 2 DS 2 VASc scores Andrikopoulos G., et al. On behalf of the MANAGE AF AF study investigators. Submitted 2014
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Andrikopoulos G., et al. On behalf of the MANAGE AF AF study investigators. Submitted 2014
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study AC*: alone or in combination with an antiplatelet Andrikopoulos G., et al. On behalf of the MANAGE AF AF study investigators. Submitted 2014
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Baseline characteristics and stroke risk factors MANAGE AF (n=603) GARFIELD 1 (n=9971) RECORD AF Euro Heart AFNET (n=5604) Survey (n=9582) (n=5333) Age (years) 68.5 70 66 (66) 68.4 Gender (male), n (%) 52.5 57 57 59 63.7 OAC treated 49.3 61.8 52.0 64.2 50.7 Stroke Risk Factors Hypertension, n (%) 70.3 77.8 68 62.2 69.2 Heart Failure, n (%) 23.3 19.1 26 32.8 29.0 Diabetes, n (%) 21.8 22.2 16 18 21.7 CAD, n (%) 20.5 19 18 32 28.1 Stroke/TIA, n (%) 9.2 14.4 10 12 12.4 N Engl J Med 2011;365(10):883 91. Am J Cardiol 2010;105(5):687 93. Eur Heart J 26 (22): 2422 2434. Europace 2009 Apr;11(4):423 34
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study Distribution of populations according to CHADS 2 Scores Average CHADS 2 Scores MANAGE AF: 1,6 GARFIELD 1: 1,9 ROCKET AF: 3,46
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study 6 μηνη προοπτική παρακολούθηση Αρχική εξέταση
AF ANTITHROMBOTICS (IMS data for Greece 12/2013) Source: IMS Rx MAT/12/2013
Kirchhof P., et al. Europace (2014) 16, 6 14
Kirchhof P., et al. Europace (2014) 16, 6 14
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study 6 μηνη προοπτική παρακολούθηση
Management of Atrial Fibrillation in Greece: the MANAGE AF AF Study 6 μηνη προοπτική παρακολούθηση After stepwise multivariable logistic regression analysis the components of CHA 2 DS 2 VASc score associated more with OAC prescription (alone or in combination with anti platelet drug) were the history of stroke or TIA and the history of heart failure or low ejection fraction (OR=1.655 with 95%CI= 1.230 2.227, p=0.001 and OR=1.714 with 95%CI=1.150 2.554, p=0.008, respectively)
Vassilikos V., et al. Hellenic J Cardiol 2012; 53: 108 117 117
Vassilikos V., et al. Hellenic J Cardiol 2012; 53: 108 117 117
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation January CT, et al. 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation. Journal of the American College of Cardiology (2014), doi: 10.1016/j.jacc.2014.03.022
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation January CT, et al. 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation. Journal of the American College of Cardiology (2014), doi: 10.1016/j.jacc.2014.03.022
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